Mechanism of activation of pyruvate dehydrogenase by dichloroacetate and other halogenated carboxylic acids

Methods of enzymatic analysis

1964 • 5,230 citations

Use of the liquid scintillation spectrometer for determining adenosine triphosphate by the luciferase enzyme

1969 • 898 citations

α-KETO ACID DEHYDROGENASE COMPLEXES, X. REGULATION OF THE ACTIVITY OF THE PYRUVATE DEHYDROGENASE COMPLEX FROM BEEF KIDNEY MITOCHONDRIA BY PHOSPHORYLATION AND DEPHOSPHORYLATION

1969 • 669 citations

Alanine: Key Role in Gluconeogenesis

1970 • 580 citations

Stimulation by calcium ions of pyruvate dehydrogenase phosphate phosphatase

1972 • 519 citations

A Rapid Enzymatic Assay for Glycerol

1962 • 454 citations

[A simple technic for extremely rapid freezing of large pieces of tissue].

1960 • 453 citations

Control of Gluconeogenesis from Amino Acids in the Perfused Rat Liver

1969 • 431 citations

Subcellular components: preparation and fractionation;

1972 • 421 citations

Regulation of adipose tissue pyruvate dehydrogenase by insulin and other hormones

1971 • 388 citations

Specific inhibition of pyruvate transport in rat liver mitochondria and human erythrocytes by α-cyano-4-hydroxycinnamate (Short Communication)

1974 • 372 citations

α-Keto acid dehydrogenase complexes

1972 • 282 citations

The effects of increased heart work on the tricarboxylate cycle and its interactions with glycolysis in the perfused rat heart

1972 • 258 citations

THE ENZYMATIC ACETYLATION OF AMINES

1953 • 209 citations

Activation of pyruvate dehydrogenase in perfused rat heart by dichloroacetate (Short Communication)

1973 • 174 citations

Calcium and magnesium ions as effectors of adipose-tissue pyruvate dehydrogenase phosphate phosphatase

1974 • 157 citations

Measurement of Cyclic 3',5'-Adenosine Monophosphate by the Activation of Skeletal Muscle Protein Kinase

1971 • 144 citations

Effects of dichloroacetate on the metabolism of glucose, pyruvate, acetate, 3-hydroxybutyrate and palmitate in rat diaphragm and heart muscle in vitro and on extraction of glucose, lactate, pyruvate and free fatty acids by dog heart in vivo

1973 • 128 citations

Mechanisms regulating adipose-tissue pyruvate dehydrogenase

1972 • 103 citations

Function of the nonidentical subunits of mammalian pyruvate dehydrogenase

1972 • 93 citations

Diisopropylammonium dichloroacetate (DIPA) and sodium dichloroacetate (DCA): Effect on glucose and fat metabolism in normal and diabetic tissue

1970 • 65 citations

Hypoglycaemic action of DIISOpropylammonium salts in experimental diabetes

1962 • 52 citations

Calcium ions and the regulation of pyruvate dehydrogenase.

1974 • 52 citations

Metabolism of pyruvate and malate by isolated fat-cell mitochondria

1971 • 32 citations

Diisopropylammonium dichloroacetate: Regulation of metabolic intermediates in muscle of alloxan diabetic rats

1971 • 28 citations