Tyrosine phosphorylation of specific proteins after mitogen stimulation of chicken embryo fibroblasts.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Epidermal Growth Factor

1979 • 2,964 citations

Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

1980 • 2,387 citations

A Platelet-Dependent Serum Factor That Stimulates the Proliferation of Arterial Smooth Muscle Cells In Vitro

1974 • 1,838 citations

Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes.

1980 • 1,184 citations

Protein kinase activity associated with the avian sarcoma virus src gene product.

1978 • 1,137 citations

Epidermal growth factor-receptor-protein kinase interactions. Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity.

1980 • 853 citations

A native 170,000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles.

1982 • 788 citations

Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor

1982 • 675 citations

Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells

1981 • 669 citations

Direct visualization of binding, aggregation, and internalization of insulin and epidermal growth factor on living fibroblastic cells

1978 • 647 citations

Platelets as a source of fibroblast growth-promoting activity

1974 • 625 citations

Vinculin: A cytoskeletal target of the transforming protein of rous sarcoma virus

1981 • 591 citations

Avian sarcoma virus-transforming protein, pp60src shows protein kinase activity specific for tyrosine

1980 • 510 citations

Vinculin, an intracellular protein localized at specialized sites where microfilament bundles terminate at cell membranes.

1980 • 502 citations

Changes in protein phosphorylation in Rous sarcoma virus-transformed chicken embryo cells.

1981 • 440 citations

Specific receptors for platelet-derived growth factor on cells derived from connective tissue and glia.

1981 • 427 citations

Increased phosphotyrosine content and inhibition of proliferation in EGF-treated A431 cells

1981 • 392 citations

Platelet-derived growth factor and the regulation of the mammalian fibroblast cell cycle

1979 • 374 citations

Similar effects of platelet-derived growth factor and epidermal growth factor on the phosphorylation of tyrosine in cellular proteins

1982 • 366 citations

Platelet-derived growth factor. II. Specific binding to cultured cells.

1982 • 366 citations

The specific interaction of the Rous sarcoma virus transforming protein, pp60src, with two cellular proteins

1981 • 360 citations

A partially purified polypeptide fraction from rat liver cell conditioned medium with multiplication‐stimulating activity for embryo fibroblasts

1973 • 335 citations

Transformation by Rous sarcoma virus: A cellular substrate for transformation-specific protein phosphorylation contains phosphotyrosine

1980 • 328 citations

Transformation by Rous sarcoma virus: effects of src gene expression on the synthesis and phosphorylation of cellular polypeptides.

1979 • 293 citations

Hexose Transport in Normal and in Rous Sarcoma Virus-transformed Cells

1973 • 281 citations

Variants of 3T3 cells lacking mitogenic response to epidermal growth factor.

1977 • 280 citations

Epidermal growth factor inhibits growth of A431 human epidermoid carcinoma in serum-free cell culture.

1982 • 280 citations

Phosphotyrosyl-protein phosphatase. Specific inhibition by Zn.

1981 • 277 citations

The purified product of the transforming gene of avian sarcoma virus phosphorylates tyrosine.

1980 • 269 citations

Hormone receptor topology and dynamics: Morphological analysis using ferritin-labeled epidermal growth factor

1979 • 254 citations

A steady state model for analyzing the cellular binding, internalization and degradation of polypeptide ligands

1981 • 236 citations

Evidence that the avian sarcoma virus transforming gene product is a cyclic AMP-independent protein kinase.

1979 • 232 citations

Affinity labeling of the protein kinase associated with the epidermal growth factor receptor in membrane vesicles from A431 cells.

1982 • 232 citations

Multiplication‐stimulating activity for chicken embryo fibroblasts from rat liver cell conditioned medium: A family of small polypeptides

1973 • 181 citations

Stimulation of Glucose Transport in Cultures of Density-Inhibited Chick Embryo Cells

1971 • 177 citations

Changes in Protein Phosphorylation in Rous Sarcoma Virus-Transformed Chicken Embryo Cells

1981 • 158 citations

Evidence that viral transforming gene products and epidermal growth factor stimulate phosphorylation of the same cellular protein with similar specificity.

1981 • 137 citations

Platelet-derived growth factor. III. Identification of a platelet-derived growth factor receptor by affinity labeling.

1982 • 137 citations

Molecular events in cells transformed by Rous Sarcoma virus.

1980 • 121 citations

Stimulation of sugar uptake in cultured fibroblasts by epidermal growth factor (EGF) and EGF‐binding arginine esterase

1976 • 121 citations

Purified multiplication-stimulating activity from rat liver cell conditioned medium: Comparison of biological activities with calf serum, insulin, and somatomedin

1974 • 120 citations

Two cellular proteins that immunoprecipitate with the transforming protein of Rous sarcoma virus

1981 • 110 citations

Dissociation of transformation parameters using temperature-conditional mutants of Rous sarcoma virus

1979 • 108 citations

Similarities and differences between the effects of epidermal growth factor and Rous sarcoma virus.

1981 • 108 citations

Distinguishable transformation-defective phenotypes among temperature-sensitive mutants of Rous sarcoma virus

1977 • 99 citations

Interaction of multiplication-stimulating activity with chick embryo fibroblasts demonstrates a growth receptor

1976 • 86 citations

Detection of a novel mammalian protein phosphatase with activity for phosphotyrosine

1981 • 80 citations

Identification of Phosphotyrosine-Containing Proteins in Untransformed and Rous Sarcoma Virus-Transformed Chicken Embryo Fibroblasts

1982 • 71 citations

A nonmitogenic analogue of epidermal growth factor induces early responses mediated by epidermal growth factor.

1982 • 64 citations

Biological properties of "partial" transformation mutants of Rous sarcoma virus and characterization of their pp60src kinase

1981 • 62 citations

A non-mitogenic analogue of epidermal growth factor enhances the phosphorylation of endogenous membrane proteins

1981 • 61 citations

Transformation by Rous Sarcoma Virus: Effects of src-gene Expression on the Synthesis and Phosphorylation of Cellular Polypeptides

1980 • 52 citations

Identification of Phosphotyrosine-Containing Proteins in Untransformed and Rous Sarcoma Virus-Transformed Chicken Embryo Fibroblasts

1982 • 45 citations

Phosphorylation of a 36,000 Mr cellular protein in cells infected with partial transformation mutants of rous sarcoma virus.

1982 • 34 citations