Maximum activities of key enzymes of glycolysis, glutaminolysis, pentose phosphate pathway and tricarboxylic acid cycle in normal, neoplastic and suppressed cells

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

On the Origin of Cancer Cells

1956 • 12,141 citations

Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells.

1979 • 1,228 citations

Biochemistry for the Medical Sciences

1983 • 960 citations

Suppression of Malignancy by Cell Fusion

1969 • 613 citations

Characteristics of a Human Diploid Cell Designated MRC-5

1970 • 593 citations

GLUTAMINE METABOLISM IN LYMPHOCYTES: ITS BIOCHEMICAL, PHYSIOLOGICAL AND CLINICAL IMPORTANCE

1985 • 455 citations

Glutamine metabolism in lymphocytes of the rat

1983 • 442 citations

Metabolism of glucose, glutamine, long-chain fatty acids and ketone bodies by murine macrophages

1986 • 404 citations

Mitochondrial metabolism of glutamine and glutamate and its physiological significance.

1983 • 372 citations

The role of high rates of glycolysis and glutamine utilization in rapidly dividing cells

1985 • 350 citations

Culture characteristics of four permanent lines of human cancer cells.

1955 • 346 citations

Glycolysis, glutaminolysis and cell proliferation

1982 • 305 citations

The Pasteur effect and the relations between respiration and fermentation.

1972 • 302 citations

Rates of utilization and fates of glucose, glutamine, pyruvate, fatty acids and ketone bodies by mouse macrophages

1987 • 300 citations

Glutamine: a major energy source for cultured mammalian cells.

1984 • 234 citations

Metabolism in lymphocytes and its importance in the immune response.

1985 • 228 citations

Glycolysis, respiration, and anomalous gene expression in experimental hepatomas: G.H.A. Clowes memorial lecture.

1972 • 227 citations

Three glycolytic enzymes are phosphorylated at tyrosine in cells transformed by Rous sarcoma virus

1983 • 225 citations

The role of glutamine in the oxidative metabolism of malignant cells.

1972 • 224 citations

Maximum activities of some enzymes of glycolysis, the tricarboxylic acid cycle and ketone-body and glutamine utilization pathways in lymphocytes of the rat

1982 • 217 citations

Rates of utilization of glucose, glutamine and oleate and formation of end-products by mouse peritoneal macrophages in culture

1989 • 215 citations

Aerobic glycolysis and lymphocyte transformation

1978 • 167 citations

Tricarboxylic acid cycle flux and enzyme activities in the isolated working rat heart

1981 • 161 citations

A Quantitative Approach to Metabolic Control

1985 • 140 citations

Membrane Cholesterol, Tumorigenesis, and the Biochemical Phenotype of Neoplasia

1981 • 120 citations

Activities of citrate synthase, NAD+-linked and NADP+-linked isocitrate dehydrogenases, glutamate dehydrogenase, aspartate aminotransferase and alanine aminotransferase in nervous tissues from vertebrates and invertebrates

1975 • 112 citations

Suppression of tumorigenicity in somatic cell hybrids

1980 • 103 citations

Alterations in Glucose Metabolism in Chick-Embryo Cells Transformed by Rous Sarcoma Virus: Intracellular Levels of Glycolytic Intermediates

1974 • 95 citations

Amino Acids and Glucose Utilization by Different Metabolic Pathways in Ascites‐Tumour Cells

1981 • 93 citations

Maximum activities and effects of fructose bisphosphate on pyruvate kinase from muscles of vertebrates and invertebrates in relation to the control of glycolysis

1978 • 92 citations

Phytohaemagglutinin stimulation of rat thymus lymphocyte glycolysis

1976 • 88 citations

SURFACE IgM SPECIFICITY ON CELLS DERIVED FROM A BURKITT'S LYMPHOMA

1967 • 82 citations

The effect of glutamine concentration on the activity of carbamoyl-phosphate synthase II and on the incorporation of [3H]thymidine into DNA in rat mesenteric lymphocytes stimulated by phytohaemagglutinin

1989 • 78 citations

Intracellular distribution of some enzymes of the glutamine utilisation pathway in rat lymphocytes

1986 • 54 citations

Use of Enzyme Activities as Indices of Maximum Rates of Fuel Utilization

1980 • 52 citations

Expression of multimolecular forms of pyruvate kinase in normal, benign, and malignant human breast tissue.

1982 • 49 citations

Hexose transport in hybrids between malignant and normal cells

1981 • 46 citations

Characterization of human keratinocyte

1981 • 44 citations

Energy substrate utilization in freshly isolated Morris Hepatoma 7777 cells.

1988 • 33 citations

Molecular events leading to enhanced glucose transport in Rous sarcoma virus-transformed cells.

1984 • 24 citations

Analysis of tricarboxylic acid-cycle metabolism of hepatoma cells by comparison of 14CO2 ratios

1987 • 21 citations