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Systematic Review and Individual Patient Data Meta-analysis of Randomized Trials Comparing a Single Immediate Instillation of Chemotherapy After Transurethral Resection with Transurethral Resection Alone in Patients with Stage pTa–pT1 Urothelial Carcinoma of the Bladder: Which Patients Benefit from the Instillation?

Data up to Jan 2025

Published2015
Citations321
References49

Total Citations Per Year

Abstract

References (49)

Predicting Recurrence and Progression in Individual Patients with Stage Ta T1 Bladder Cancer Using EORTC Risk Tables: A Combined Analysis of 2596 Patients from Seven EORTC Trials

2006 • 2,702 citations

EAU Guidelines on Non–Muscle-invasive Urothelial Carcinoma of the Bladder: Update 2016

2016 • 2,126 citations

EAU Guidelines on Non–Muscle-invasive Urothelial Carcinoma of the Bladder: Update 2013

2013 • 1,133 citations

Guideline for the Management of Nonmuscle Invasive Bladder Cancer (Stages Ta, T1, and Tis): 2007 Update

2007 • 832 citations

A SINGLE IMMEDIATE POSTOPERATIVE INSTILLATION OF CHEMOTHERAPY DECREASES THE RISK OF RECURRENCE IN PATIENTS WITH STAGE Ta T1 BLADDER CANCER: A META-ANALYSIS OF PUBLISHED RESULTS OF RANDOMIZED CLINICAL TRIALS

2004 • 733 citations

A Prospective European Organization for Research and Treatment of Cancer Genitourinary Group Randomized Trial Comparing Transurethral Resection Followed by a Single Intravesical Instillation of Epirubicin or Water in Single Stage Ta, T1 Papillary Carcinoma of the Bladder

1993 • 367 citations

The Effect of Intravesical Mitomycin C on Recurrence of Newly Diagnosed Superficial Bladder Cancer: A Further Report with 7 Years of Followup

1996 • 325 citations

Apparent Failure of Current Intravesical Chemotherapy Prophylaxis to Influence the Long-Term Course of Superficial Transitional Cell Carcinoma of the Bladder

1995 • 194 citations

The Schedule and Duration of Intravesical Chemotherapy in Patients with Non–Muscle-Invasive Bladder Cancer: A Systematic Review of the Published Results of Randomized Clinical Trials

2008 • 188 citations

STAGE PROGRESSION IN TA PAPILLARY UROTHELIAL TUMORS: RELATIONSHIP TO GRADE, IMMUNOHISTOCHEMICAL EXPRESSION OF TUMOR MARKERS, MITOTIC FREQUENCY AND DNA PLOIDY

2001 • 187 citations

Effectiveness of a single immediate mitomycin C instillation in patients with low risk superficial bladder cancer: short and long-term follow-up.

2007 • 181 citations

Should All Patients with Non–Muscle-Invasive Bladder Cancer Receive Early Intravesical Chemotherapy after Transurethral Resection? The Results of a Prospective Randomised Multicentre Study

2009 • 173 citations

Original Articles: Bladder Cancer: Intravesical Adjuvant Chemotherapy for Superficial Transitional Cell Bladder Carcinoma: Results of 2 European Organization for Research and Treatment of Cancer Randomized Trials With Mitomycin C and Doxorubicin Comparing Early Versus Delayed Instillations and Short-Term Versus Long-Term Treatment

1995 • 171 citations

Immediate Post–Transurethral Resection of Bladder Tumor Intravesical Chemotherapy Prevents Non–Muscle-invasive Bladder Cancer Recurrences: An Updated Meta-analysis on 2548 Patients and Quality-of-Evidence Review

2013 • 142 citations

Management of Low Grade Papillary Bladder Tumors

2007 • 136 citations

Electromotive instillation of mitomycin immediately before transurethral resection for patients with primary urothelial non-muscle invasive bladder cancer: a randomised controlled trial

2011 • 132 citations

Intravesical adjuvant chemotherapy for superficial transitional cell bladder carcinoma : results of 2 european organization for research and treatment of cancer randomized trials with Mitomycin C and Doxorubicin comparing early versus delayed instillations and short-term versus long-term treatment

1995 • 124 citations

One Immediate Postoperative Instillation of Chemotherapy in Low Risk Ta, T1 Bladder Cancer Patients. Is it Always Safe?

2004 • 117 citations

Effect of intravesical mitomycin C on recurrence of newly diagnosed superficial bladder cancer: interim report from the Medical Research Council Subgroup on Superficial Bladder Cancer (Urological Cancer Working Party)

1988 • 104 citations

Re: A Single Instillation of Epirubicin After Transurethral Resection of Bladder Tumors Prevents Only Small Recurrences

2008 • 99 citations

Perioperative Intravesical Chemotherapy in Non–Muscle-Invasive Bladder Cancer: A Systematic Review and Meta-Analysis

2013 • 92 citations

Single‐dose versus multiple instillations of epirubicin as prophylaxis for recurrence after transurethral resection of pTa and pT1 transitional‐cell bladder tumours: a prospective, randomized controlled study

1997 • 92 citations

A Single Instillation of Epirubicin After Transurethral Resection of Bladder Tumors Prevents Only Small Recurrences

2007 • 89 citations

Randomized study of single early instillation of (2″R)‐4′‐O‐tetrahydropyranyl‐doxorubicin for a single superficial bladder carcinoma

2002 • 86 citations

Long‐term outcome of bladder papillary urothelial neoplasms of low malignant potential

2003 • 84 citations

Perioperative single dose instillation of epirubicin or interferon-alpha after transurethral resection for the prophylaxis of primary superficial bladder cancer recurrence: a prospective randomized multicenter study--FinnBladder III long-term results.

2002 • 84 citations

National Practice Patterns for Immediate Postoperative Instillation of Chemotherapy in Nonmuscle Invasive Bladder Cancer

2012 • 75 citations

Adjuvant Chemotherapy for Superficial Transitional Cell Bladder Carcinoma: Long-term Results of a European Organization for Research and Treatment of Cancer Randomized Trial Comparing Doxorubicin, Ethoglucid and Transurethral Resection Alone

1997 • 70 citations

Can Early Single Dose Instillation of Epirubicin Improve Bacillus Calmette-Guerin Efficacy in Patients With Nonmuscle Invasive High Risk Bladder Cancer? Results From a Prospective, Randomized, Double-Blind Controlled Study

2008 • 67 citations

Perioperative Single Dose Instillation of Epirubicin or Interferon-α After Transurethral Resection for The Prophylaxis of Primary Superficial Bladder Cancer Recurrence: A Prospective Randomized Multicenter Study—Finnbladder III Long-Term Results

2002 • 66 citations

The Effect of Intravesical Thiotepa on the Recurrence Rate of Newly Diagnosed Superficial Bladder Cancer. An MRC Study

1985 • 65 citations

INHIBITION OF TUMOR IMPLANTATION BY INTRAVESICAL GEMCITABINE IN A MURINE MODEL OF SUPERFICIAL BLADDER CANCER

2005 • 57 citations

TRANSURETHRAL RESECTION WITH PERIOPERATIVE INSTILLATION OF INTERFERON-alpha OR EPIRUBICIN FOR THE PROPHYLAXIS OF RECURRENT PRIMARY SUPERFICIAL BLADDER CANCER: A PROSPECTIVE RANDOMIZED MULTICENTER STUDY-FINNBLADDER III

1999 • 54 citations

DuCaP AND VCaP ARE ANDROGEN-DEPENDENT PROSTATE CANCER CELL LINES THAT FORM OSTEOBLASTIC BONE METASTASES

2008 • 52 citations

Inhibition of Implantation of Murine Bladder Tumor by Thiotepa in Cauterized Bladder

1989 • 50 citations

The effect of intravesical thiotepa on tumour recurrence after endoscopic treatment of newly diagnosed superficial bladder cancer. A further report with long‐term follow‐up of a Medical Research Council randomized trial

1994 • 48 citations

Long-term experience with early single Mitomycin C instillations in patients with low-risk non-muscle-invasive bladder cancer: prospective, single-centre randomised trial

2011 • 48 citations

Understanding the Use of Immediate Intravesical Chemotherapy for Patients with Bladder Cancer

2012 • 45 citations

The use of immediate postoperative instillations of intravesical chemotherapy after TURBT of NMIBC among European countries

2013 • 42 citations

Destruction of the bladder by single dose Mitomycin <scp>C</scp> for low‐stage transitional cell carcinoma (<scp>TCC</scp>) – avoidance, recognition, management and consent

2013 • 38 citations

Perforation during TUR of bladder tumours influences the natural history of superficial bladder cancer

2013 • 35 citations

Economic and Humanistic Consequences of Preventable Bladder Tumor Recurrences in Nonmuscle Invasive Bladder Cancer Cases

2012 • 30 citations

Immediate intravesical instillation of mitomycin C after transurethral resection of bladder tumor in patients with low-risk superficial transitional cell carcinoma of bladder.

2006 • 18 citations

Early Single-Instillation Chemotherapy Has No Real Benefit and Should Be Abandoned in Non–Muscle-Invasive Bladder Cancer

2009 • 15 citations

Preliminary results of a MRC randomised controlled trial of post-operative irrigation of superficial bladder cancer

2001 • 14 citations

TaG1 Bladder Cancer: A Third of All Primary Tumors and 80% of All Recurrences Can Be Treated in the Office Using Local Anesthesia

2014 • 7 citations

Effects of Intravesical Mitomycin and Distilled Water on Recurrence After TUR-TM in Ta, T1 Tumors

2011 • 4 citations

[Adjuvant thio-tepa in the treatment of bladder papilloma. A prospective randomized study].

1980 • 1 citations

C108 ADJUVANT INSTILLATION THERAPY IN THE TREATMENT OF NON-MUSCLE INVASIVE BLADDER CANCER DURING THE FIRST TWO YEARS AFTER TRANSURETHRAL RESECTION

2010 • 1 citations

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Systematic Review and Individual Patient Data Meta-analysis of Randomized Trials… (2015) – European Urology | Metascience Observatory Explorer