Cloning and analysis of human gastric mucin cDNA reveals two types of conserved cysteine-rich domains

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Physiology of the Gastrointestinal Tract

2006 • 4,704 citations

Physiology of the Gastrointestinal Tract.

1982 • 1,635 citations

Optimal alignments in linear space

1988 • 1,229 citations

Mucin-Type Glycoproteins

1992 • 902 citations

Why are proteins O-glycosylated?

1990 • 708 citations

Molecular Cloning of Human Intestinal Mucin cDNAs

1989 • 544 citations

Expression of human mucin genes in respiratory, digestive, and reproductive tracts ascertained by in situ hybridization.

1993 • 455 citations

Physiology of the Gastrointestinal Tract

1988 • 438 citations

Molecular cloning of human intestinal mucin (MUC2) cDNA. Identification of the amino terminus and overall sequence similarity to prepro-von Willebrand factor.

1994 • 428 citations

The CTAB-DNA precipitation method: a common mini-scale preparation of template DNA from phagemids, phages or plasmids suitable for sequencing.

1989 • 414 citations

Molecular cloning and chromosomal localization of a novel human tracheo-bronchial mucin cDNA containing tandemly repeated sequences of 48 base pairs

1991 • 405 citations

Episialin, a carcinoma-associated mucin, is generated by a polymorphic gene encoding splice variants with alternative amino termini.

1990 • 376 citations

Human gastric mucin. Identification of a unique species by expression cloning.

1993 • 370 citations

Molecular cloning of cDNAs derived from a novel human intestinal mucin gene

1990 • 367 citations

Amino acid distributions around O-linked glycosylation sites

1991 • 278 citations

The human MUC2 intestinal mucin has cysteine-rich subdomains located both upstream and downstream of its central repetitive region.

1992 • 270 citations

Biosynthesis of human colonic mucin: Muc2 is the prominent secretory mucin

1994 • 247 citations

Isolation and characterization of human cervical-mucus glycoproteins

1983 • 229 citations

Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).

1994 • 222 citations

Vicinal cysteines in the prosequence play a role in von Willebrand factor multimer assembly.

1992 • 213 citations

Structure of pre-pro-von Willebrand factor and its expression in heterologous cells

1986 • 212 citations

cDNA sequences for human von Willebrand factor reveal five types of repeated domains and five possible protein sequence polymorphisms

1986 • 204 citations

MUC-2 human small intestinal mucin gene structure. Repeated arrays and polymorphism.

1991 • 187 citations

The specificity of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase as inferred from a database of in vivo substrates and from the in vitro glycosylation of proteins and peptides

1993 • 173 citations

Mannose 6-phosphate-independent membrane association of cathepsin D, glucocerebrosidase, and sphingolipid-activating protein in HepG2 cells.

1991 • 156 citations

Expression of variant von Willebrand factor (vWF) cDNA in heterologous cells: requirement of the pro-polypeptide in vWF multimer formation.

1987 • 127 citations

Mucus glycoproteins from ‘normal’ human tracheobronchial secretion

1990 • 125 citations

Human gastric (H+ + K+)-ATPase gene. Similarity to (Na+ + K+)-ATPase genes in exon/intron organization but difference in control region.

1990 • 124 citations

Evidence for Different Human Tracheobronchial Mucin Peptides Deduced from Nucleotide cDNA Sequences

1991 • 122 citations

Porcine submaxillary mucin contains a cystine-rich, carboxyl-terminal domain in addition to a highly repetitive, glycosylated domain

1991 • 103 citations

Covalent oligomerization of rat gastric mucin occurs in the rough endoplasmic reticulum, is N-glycosylation-dependent, and precedes initial O-glycosylation.

1990 • 99 citations

A new repetitive protein from Xenopus laevis skin highly homologous to pancreatic spasmolytic polypeptide.

1988 • 97 citations

Complex structure of human bronchial mucus glycoprotein

1984 • 90 citations

cDNA for the carboxyl-terminal region of a rat intestinal mucin-like peptide.

1992 • 88 citations

Cloning and cDNA sequence of a bovine submaxillary gland mucin-like protein containing two distinct domains.

1990 • 85 citations

Synthesis and secretion of mucin by the human colonic tumour cell line LS180

1994 • 71 citations

Influence of acceptor substrate primary amino acid sequence on the activity of human UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferase. Studies with the MUC1 tandem repeat.

1994 • 71 citations

von Willebrand Factor Biosynthesis and Processinga

1991 • 67 citations

Further evidence for a flexible and highly expanded spheroidal model for mucus glycoproteins in solution

1983 • 55 citations

Proteolytic fragmentation and peptide mapping of human carboxyamidomethylated tracheobronchial mucin

1989 • 52 citations

Biosynthesis of Gastric Mucus Glycoprotein of the Rat

1989 • 52 citations

P-domains as shuffled cysteine-rich modules in integumentary mucin C.1 (FIM-C.1) from Xenopus laevis. Polydispersity and genetic polymorphism.

1992 • 51 citations

Human Pepsinogen C (Progastriesin)

1989 • 49 citations

Electron microscopy of cervical-mucus glycoproteins and fragments therefrom. The use of colloidal gold to make visible ‘naked’ protein regions

1990 • 42 citations

Isolation and structural analysis of rat gastric mucus glycoprotein suggests a homogeneous protein backbone

1989 • 38 citations

The oligomeric structure of rat and human gastric mucins

1991 • 38 citations

The role of disulphide bonds in human intestinal mucin

1979 • 36 citations

Identification of a human gastric mucin precursor: N-linked glycosylation and oligomerization

1994 • 31 citations

The polymorphic integumentary mucin B.1 from Xenopus laevis contains the short consensus repeat.

1992 • 24 citations

Rat gastric mucin is synthesized and secreted exclusively as filamentous oligomers

1991 • 23 citations