Thermodynamics and the structure of biological macromolecules

Principles of Polymer Chemistry.

1954 • 16,197 citations

Principles of polymer chemistry

1995 • 15,622 citations

NMR with Proteins and Nucleic Acids

1986 • 7,896 citations

NMR of Proteins and Nucleic Acids

2006 • 5,989 citations

Encyclopedia of polymer science and engineering

1985 • 5,821 citations

Encyclopedia of polymer science and engineering

1987 • 4,209 citations

Eine neue Bestimmung der Moleküldimensionen

1906 • 3,895 citations

Physical chemistry of macromolecules

2007 • 3,839 citations

The physical chemistry of electrolytic solutions

1950 • 3,057 citations

The molecular theory of polyelectrolyte solutions with applications to the electrostatic properties of polynucleotides

1978 • 2,873 citations

Chromatin Structure: A Repeating Unit of Histones and DNA

1974 • 2,514 citations

Physical chemistry of macromolecules

1962 • 2,105 citations

Procedures in Nucleic Acid Research.

1967 • 2,043 citations

Röntgenuntersuchung gelöster Fadenmoleküle

1949 • 1,888 citations

Thermodynamic analysis of ion effects on the binding and conformational equilibria of proteins and nucleic acids: the roles of ion association or release, screening, and ion effects on water activity

1978 • 1,651 citations

The locus of sequence-directed and protein-induced DNA bending

1984 • 1,453 citations

Structure of a Ribonucleic Acid

1965 • 1,370 citations

Eine neue Bestimmung der Moleküldimensionen

1906 • 1,267 citations

Solenoidal model for superstructure in chromatin.

1976 • 1,223 citations

The replication of DNA in Escherichia coli

1958 • 1,202 citations

Chromatin sub-structure. The digestion of chromatin DNA at regularly spaced sites by a nuclear deoxyribonuclease

1973 • 1,176 citations

Structure of the nucleosome core particle at 7 Å resolution

1984 • 1,028 citations

Ion effects on ligand-nucleic acid interactions

1976 • 1,016 citations

Procedures in nucleic acid research

1966 • 987 citations

Viscosity and sedimentation study of sonicated DNA–proflavine complexes

1969 • 962 citations

Thermodynamic Analysis of Multicomponent Solutions

1964 • 717 citations

Ueber die Beziehung zwischen der Fortpflanzungsgeschwindigkeit des Lichtes und der Körperdichte

1880 • 709 citations

The Influence of Brownian Movement on the Viscosity of Solutions.

1940 • 700 citations

Light Scattering from Non-Gaussian Chains

1953 • 690 citations

Ueber die Refractionsconstante

1880 • 640 citations

Chromatin

1989 • 606 citations

Chromatin

1978 • 569 citations

The amino-acid sequence in the glycyl chain of insulin. 1. The identification of lower peptides from partial hydrolysates

1953 • 540 citations

The Potential of an Infinite Rod-Like Molecule and the Distribution of the Counter Ions

1951 • 539 citations

Basic Principles in Nucleic Acid Chemistry

1974 • 523 citations

The effect of volume occupancy upon the thermodynamic activity of proteins: some biochemical consequences

1983 • 503 citations

Chemical physics of ionic solutions

1967 • 491 citations

Ordered water structure around a B-DNA dodecamer

1983 • 482 citations

THE ROLE OF THE NUCLEAR MATRIX IN THE ORGANIZATION AND FUNCTION OF DNA

1986 • 360 citations

Modern Aspects of Electrochemistry.

1955 • 345 citations

The counterion distribution in solutions of rod‐shaped polyelectrolytes

1951 • 342 citations

Deoxyribonueleate solutions: Sedimentation in a density gradient, partial specific volumes, density and refractive index increments, and preferential interactions

1968 • 328 citations

Ultracentrifuge Studies with Absorption Optics. IV. Molecular Weight Determinations at the Microgram Level^*

1966 • 318 citations

Curved DNA: design, synthesis, and circularization.

1986 • 303 citations

The Genetic Control of Tertiary Protein Structure: Studies With Model Systems

1963 • 301 citations

Chemical physics of ionic solutions

1967 • 294 citations

Multiple liquid crystal phases of DNA at high concentrations

1988 • 283 citations

Water: An Integral Part of Nucleic Acid Structure

1988 • 280 citations

ENZYMES UNDER EXTREMES OF PHYSICAL CONDITIONS

1981 • 275 citations

SIMPLIFIED ROTATING CYLINDER VISCOMETER FOR DNA

1962 • 271 citations

Variability of the intracellular ionic environment of Escherichia coli. Differences between in vitro and in vivo effects of ion concentrations on protein-DNA interactions and gene expression.

1987 • 270 citations

Nucleic acids and nuclear magnetic resonance

1988 • 269 citations

Replacement of potassium chloride by potassium glutamate dramatically enhances protein-DNA interactions in vitro

1987 • 267 citations

Structure of the 3000Å chromatin filament: X-ray diffraction from oriented samples

1985 • 267 citations

The electrostatic potential of B‐DNA

1989 • 263 citations

Polyelectrolytes

1972 • 262 citations

The amino-acid sequence in the glycyl chain of insulin. 2. The investigation of peptides from enzymic hydrolysates

1953 • 247 citations

Chromatin fibers are left-handed double helices with diameter and mass per unit length that depend on linker length

1986 • 244 citations

Curved DN

1985 • 236 citations

Studies of the temperature-dependent conformation and phase separation of polyriboadenylic acid solutions at neutral pH

1967 • 229 citations

The dimensions of charged long chain molecules in solutions containing electrolytes

1948 • 209 citations

Monomolecular condensation of λ‐DNA induced by cobalt hexammine

1983 • 205 citations

Nucleotide sequence and gene organization of ColE1 DNA.

1985 • 201 citations

Monte Carlo determination of the distribution of ions about a cylindrical polyelectrolyte

1984 • 196 citations

Ribonucleic acid from Escherichia coli preparation, characterization and physical properties

1959 • 190 citations

Structure of the 30 nm chromatin fiber

1986 • 190 citations

Verhalten polyvalenter Fadenmolekelionen in Lösung

1948 • 189 citations

Biological Macromolecules and Polyelectrolytes in Solution

1976 • 183 citations

Interpretation of equilibrium sedimentation measurements of proteins in guanidine hydrochloride solutions. Partial volumes, density increments, and the molecular weight of the subunits of rabbit muscle aldolase

1969 • 182 citations

Macromolecular crowding increases binding of DNA polymerase to DNA: an adaptive effect.

1987 • 178 citations

Size of DNA determined by viscoelastic measurements: Results on bacteriophages, Bacillus subtilis and Escherichia coti

1972 • 176 citations

Molecular weight of the subunits, oligomeric and associated forms of bovine liver glutamate dehydrogenase

1968 • 171 citations

Refractive Index and dispersion of distilled water for visible radiation, at temperatures 0 to 60 degrees C

1938 • 170 citations

Dependence of laser light scattering of DNA on NaCl concentration

1981 • 162 citations

Crystallographic Structure of the Octameric Histone Core of the Nucleosome at a Resolution of 3.3 Å

1985 • 155 citations

Ionic distributions near polyelectrolytes. A comparison of theoretical approaches

1985 • 148 citations

Equation of swelling for polyelectrolyte gels

1951 • 148 citations

Structure of DNA hydration shells studied by Raman spectroscopy

1989 • 144 citations

Dependence of DNA conformation on the concentration of salt

1981 • 142 citations

Viscosities of dilute aqueous solutions of a partially quaternized poly‐4‐vinylpyridine at low gradients of flow

1954 • 127 citations

Stabilization of halophilic malate dehydrogenase

1989 • 118 citations

Archaebacteria and Archezoa

1989 • 114 citations

Bolaform Electrolytes. I. Di-(β-trimethylammonium Ethyl) Succinate Dibromide and Related Compounds¹

1951 • 109 citations

Structure and Activity of Malate Dehydrogenase from the Extreme Halophilic Bacteria of the Dead Sea. 1. Conformation and interaction with Water and Salt between 5 M and 1 M NaCl Concentration

1981 • 109 citations

Interaction of chromatin with NaCl and MgCl2

1984 • 106 citations

STRUCTURAL STUDIES OF HALOPHILIC PROTEINS, RIBOSOMES, AND ORGANELLES OF BACTERIA ADAPTED TO EXTREME SALT CONCENTRATIONS

1987 • 103 citations

Bovine serum albumin in aqueous guanidine hydrochloride solutions. Preferential and absolute interactions and comparison with other systems

1977 • 99 citations

An erythrocyte-specific protein that binds to the poly(dG) region of the chicken beta-globin gene promoter.

1988 • 99 citations

Statistical mechanics of the B----Z transition of DNA: contribution of diffuse ionic interactions.

1984 • 97 citations

Equation for the Refractive Index of Water

1965 • 95 citations

Aqueous Solutions of Polyvinylsulfonic Acid: Phase Separation and Specific. Interactions with Ions, Viscosity, Conductance and Potentiometry

1959 • 94 citations

Forward scattering of light, X-rays and neutrons

1981 • 93 citations

Malate dehydrogenase isolated from extremely halophilic bacteria of the Dead Sea. 1. Purification and molecular characterization

1977 • 93 citations

Phylogenetic analysis based on rRNA sequences supports the archaebacterial rather than the eocyte tree

1989 • 92 citations

Structure and Viscosity of Interpenetrating Polyelectrolyte Chains

1987 • 90 citations

Binding of additional histones to chromatin core particles

1978 • 87 citations

Isolation and physical studies of the intact supercoiled

1978 • 84 citations

Crystals of a nucleosome core particle containing defined sequence DNA

1988 • 78 citations

Ions as regulators of protein-nucleic acid interactions in vitro and in vivo

1985 • 78 citations

Structure and Activity of Malate Dehydrogenase from the Extreme Halophilic Bacteria of the Dead Sea. 2. Inactivation, Dissociation and Unfolding at NaCl Concentrations below 2 M. Salt, Salt Concentration and Temperature Dependence of Enzyme Stability

1981 • 76 citations

Biological Macromolecules and Polyelectrolytes in Solution

1977 • 75 citations

Purification and characterization of a highly acidic 2Fe-ferredoxin from Halobacterium of the Dead Sea

1978 • 74 citations

DNA bending is induced by a transcription factor that interacts with the human c-FOS and alpha-actin promoters.

1989 • 72 citations

Purification and characterization of glutamate dehydrogenase from Halobacterium of the Dead Sea

1978 • 70 citations

Hydrogen Bonding and Ionization of Carboxylic Acids in Aqueous Solutions

1951 • 67 citations

Counterion exchange reactions on DNA: Monte Carlo and Poisson–Boltzmann analysis

1988 • 64 citations

Bovine Liver Glutamate Dehydrogenase

1976 • 63 citations

Molecular biology of archaebacteria

1986 • 62 citations

Viscosity of dilute solutions of preparations of deoxyribonucleic acid at low and medium rates of shear

1957 • 62 citations

Solution structure of halophilic malate dehydrogenase from small-angle neutron and X-ray scattering and ultracentrifugation

1986 • 62 citations

Hydrodynamic studies of the interaction between nucleosome core particles and core histones

1981 • 60 citations

Light Scattering of Water, Deuterium Oxide, and Other Pure Liquids

1965 • 59 citations

The superstructure of chromatin and its condensation mechanism

1987 • 58 citations

Equation of state of a random network, continuum model of liquid water

1989 • 56 citations

High-molecular-weight ribonucleic acid from rat liver

1959 • 56 citations

Interaction and conformational changes of chromatin with divalent ions

1984 • 55 citations

Isolation and characterization of the rRNA gene clusters of Halobacterium marismortui

1989 • 53 citations

Malate dehydrogenase from the extreme halophilic archaebacterium Halobacterium marismortui. Reconstitution of the enzyme after denaturation and dissociation in various denaturants

1989 • 51 citations

Harmonic vibrations and thermodynamic stability of a DNA oligomer in monovalent salt solution.

1989 • 45 citations

Polyvinylphosphate Contractile Systems

1950 • 45 citations

Transition of chromatin from the “10 nm” lower order structure, to the “30 nm” higher order structure as followed by small angle X-ray scattering

1987 • 43 citations

The Ionization Constants of Weak Acids at 25° from Conductance Measurements. A Method of Extrapolating the Data¹

1940 • 41 citations

Refractive Indices and Piezo-optic Coefficients of Deuterium Oxide, Methanol, and Other Pure Liquids

1965 • 40 citations

Conformation of LiDNA in solutions of LiCl

1984 • 37 citations

DNA flexing, folding, and function

1987 • 36 citations

Configuration‐dependent properties of randomly coiling polynucleotide chains. I. A comparison of theoretical energy estimates

1975 • 35 citations

Solution structure of a short DNA fragment studied by neutron scattering

1986 • 34 citations

HYDRODYNAMIC AND THERMODYNAMIC STUDIES

1974 • 34 citations

An interpretation of the low-angle X-ray scattering of DNA solutions

1968 • 34 citations

Étude, par diffusion centrale des Rayons X, des polyelectrolytes rigides en solution. Cas des sels de Li, Na et Cs du DNA

1967 • 32 citations

Denaturation of a halophilic enzyme monitored by small-angle neutron scattering

1986 • 32 citations

Nucleosome core particle structure and structural changes in solution

1985 • 31 citations

Configuration‐dependent properties of randomly coiling polynucleotide chains. II. The role of the phosphodiester linkage

1975 • 29 citations

Precision rotation viscometer with electrostatic restoring torque for the centipoise range

1954 • 29 citations

Glutamate dehydrogenase. Anatomy of a regulatory enzyme

1971 • 29 citations

Equation of swelling for polyelectrolyte gels, (J. polymer sci., 7, 571‐574, 1951)

1952 • 25 citations

Polyelectrolytes, thirty years later

1977 • 24 citations

Structure of phenylalanine-accepting transfer ribonucleic acid and of its environment in aqueous solvents with different salts

1988 • 24 citations

Molecular weights from equilibrium sedimentation in a density gradient

1967 • 23 citations

A brief note concerning archaebacterial phylogeny

1989 • 23 citations

Structure of halophilic malate dehydrogenase in multimolar KCl solutions from neutron scattering and ultracentrifugation

1987 • 23 citations

Light Scattering and the Structure of Pure Water

1964 • 20 citations

The histone octamer, a conformationally flexible structure

1987 • 20 citations

The Structure of DNA as Determined by X-ray Scattering Techniques

1963 • 20 citations

Crystallization of halophilic malate dehydrogenase from Halobacterium marismortui

1988 • 18 citations

Bolaform Electrolytes. III.¹ Conductance of Bisquaternary Salts of Dicarboxylic Acid Bis-β-tertiaryaminoalkyl Amides in Methanol

1953 • 18 citations

Molecular basis for the special properties of proteins and enzymes fromHalobacterium marismortui

1986 • 16 citations

Recommendations for the presentation of thermodynamic and related data in biology (1985)

1985 • 14 citations

Science as she is wrote

1989 • 3 citations

Dicarboxylic Acid Bis-(beta-Tertiaryaminoalkyl) Amides as Curare Substitutes

1950 • 3 citations

Errat

1969 • 2 citations