Adenosine deaminase deficiency: enzyme replacement therapy and investigations of the biochemical basis of immunodeficiency

ADENOSINE-DEAMINASE DEFICIENCY IN TWO PATIENTS WITH SEVERELY IMPAIRED CELLULAR IMMUNITY

1972 • 1,654 citations

Replacement Therapy for Inherited Enzyme Deficiency

1973 • 301 citations

Pyrimidine Starvation Induced by Adenosine in Fibroblasts and Lymphoid Cells: Role of Adenosine Deaminase

1973 • 271 citations

Severe Combined Immunodeficiency and Adenosine Deaminase Deficiency

1975 • 251 citations

Enzyme Replacement Therapy for Adenosine Deaminase Deficiency and Severe Combined Immunodeficiency

1976 • 249 citations

Effect of Cyclic 3',5'-Adenosine Monophosphate and Theophylline on Lymphocyte Transformation

1970 • 157 citations

Human adenosine deaminase. Purification and subunit structure.

1977 • 154 citations

Effects of lithium on brain adenyl cyclase activity

1971 • 151 citations

ADENOSINE-DEAMINASE DEFICIENCY AND COMBINED IMMUNODEFICIENCY SYNDROME

1972 • 133 citations

RESTORATION OF IN-VITRO LYMPHOCYTE RESPONSES WITH EXOGENOUS ADENOSINE DEAMINASE IN A PATIENT WITH SEVERE COMBINED IMMUNODEFICIENCY

1975 • 129 citations

RECONSTITUTION OF B AND T LYMPHOCYTE FUNCTION IN SEVERE COMBINED IMMUNODEFICIENCY DISEASE AFTER TRANSPLANTATION WITH THYMIC EPITHELIUM

1976 • 107 citations

Human adenosine deaminase

1979 • 107 citations

ADENOSINE-DEAMINASE DEFICIENCY IN A CHILD DIAGNOSED PRENATALLY

1975 • 106 citations

Purification of human erythrocyte adenosine deaminase by affinity column chromatography.

1976 • 97 citations

Role of Cyclic Adenosine 3′,5′-Monophosphate in Lymphocyte Mitogenesis

1974 • 96 citations

Combined Immunodeficiency Disease and Adenosine Deaminase Deficiency. A Molecular Defect

1976 • 85 citations

Purine nucleoside metabolism in the erythrocytes of patients with adenosine deaminase deficiency and severe combined immunodeficiency.

1976 • 84 citations

Purine Metabolism in Man

1974 • 80 citations

Effect of lithium on prostaglandin E1− stimulated adenylate cyclase activity of human platelets

1974 • 74 citations

Increased purine nucleotides in adenosinedeaminase-deficient lymphocytes

1977 • 74 citations

Heterogeneity of phenotypic expression in a family with Swiss-type agammaglobulinemia: Observations on the acquisition of agammaglobulinemia

1971 • 60 citations

Demonstration of an adenosine receptor on human lymphocytes in vitro and its possible role in the adenosine deaminase-deficient form of severe combined immunodeficiency

1978 • 58 citations

CIRCULATING THYMIC-HORMONE ACTIVITY IN CONGENITAL IMMUNODEFICIENCY

1977 • 57 citations

Enzyme Therapy. V. In Vivo Fate of Erythrocyte-entrapped β-Glucuronidase in β-Glucuronidase-deficient mice

1975 • 52 citations

Mediation of reduced nicotinamide adenine dinucleotide phosphate dependent reduction of cytochrome c by morphine

1974 • 34 citations

Lymphocyte Enzyme Deficiencies and The Metabolic Basis of Immunodeficiency Disease

1977 • 13 citations

IMMUNOPHARMACOLOGIC STUDIES OF ADENOSINE DEAMINASE DEFICIENT LYMPHOCYTES

1977 • 8 citations

EFFECT OF RBC TRANSFUSIONS ON ADENOSINE DEAMINASE(ADA) DEFICIENT SEVERE COMBINED IMMUNODEFICIENCY(SCID)

1977 • 3 citations