[24] Radiation inactivation of membrane components and molecular mass determination by target analysis

The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA

1984 • 1,386 citations

Monoamine oxidase : structure, function, and altered functions

1979 • 482 citations

Membrane enzyme systems molecular size determinations by radiation inactivation

1968 • 358 citations

Sarcoplasmic Reticulum

1970 • 288 citations

Activation of adenylate cyclase in hepatic membranes involves interactions of the catalytic unit with multimeric complexes of regulatory proteins.

1979 • 211 citations

Characterization of the insulin receptor in its membrane environment by radiation inactivation.

1980 • 131 citations

The influence of low temperature on the radiation sensitivity of enzymes.

1982 • 123 citations

Molecular and chemical characterization of membrane receptors

1984 • 123 citations

Exchange of partners in glucagon receptor-adenylate cyclase complexes. Physical evidence for the independent, mobile receptor model

1977 • 113 citations

The functional and physical form of mammalian cytochrome c oxidase determined by gel filtration, radiation inactivation, and sedimentation equilibrium analysis.

1984 • 102 citations

Molecular properties of the slow inward calcium channel. Molecular weight determinations by radiation inactivation and covalent affinity labeling.

1983 • 99 citations

Target size of calcium pump protein from skeletal muscle sarcoplasmic reticulum.

1984 • 91 citations

The Energy Loss of Electrons in Solids

1964 • 89 citations

The molecular weights of UDP-glucuronyltransferase determined with radiation-inactivation analysis. A molecular model of bilirubin UDP-glucuronyltransferase.

1984 • 89 citations

The size of the mammalian lung β2-adrenergic receptor as determined by target size analysis and immunoaffinity chromatography

1982 • 88 citations

Size of acetylcholine receptors in the membrane. An improved version of the radiation inactivation method

1982 • 86 citations

Target molecular weight of the gastric (H+ + K+)-ATPase functional and structural molecular size.

1981 • 83 citations

The Benzodiazepine/GABA Receptor Complex: Molecular Size in Brain Synaptic Membranes and in Solution

1982 • 83 citations

Lipoprotein lipase: size of the functional unit determined by radiation inactivation

1983 • 80 citations

Determination of the molecular size of the nitrendipine-sensitive Ca2+ channel by radiation inactivation

1983 • 69 citations

Target size of D-beta-hydroxybutyrate dehydrogenase. Functional and structural molecular weight based on radiation inactivation.

1983 • 65 citations

Radiation inactivation studies of the renal brush-border membrane phlorizin-binding protein.

1982 • 65 citations

Sulfhydryl/disulfide forms of rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase.

1985 • 62 citations

Molecular size of bovine lipoprotein lipase as determined by radiation inactivation.

1985 • 62 citations

Target size analysis and molecular properties of Ca²⁺ channels labelled with [³H]verapamil

1984 • 62 citations

(—)‐[³H]Desmethoxyverapamil, a novel Ca²⁺ channel probe

1984 • 60 citations

Molecular size of the hepatic receptor for asialoglycoproteins determined in situ by radiation inactivation.

1981 • 56 citations

Radiation Inactivation of Glutamate Dehydrogenase Hexamer: Lack of Energy Transfer Between Subunits

1983 • 55 citations

Molecular size of different neurotoxin receptors on the voltage-sensitive Na+ channel.

1983 • 54 citations

Functional size of rat hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase as determined by radiation inactivation.

1985 • 53 citations

Radiation inactivation of the glycoprotein, invertase.

1982 • 53 citations

Radiation target analysis of glycoproteins

1986 • 52 citations

In situ molecular weight determination of brain and peripheral benzodiazepine binding sites

1981 • 52 citations

Radiation inactivation of (Na,K)-ATPase, an enzyme showing multiple radiation-sensitive domains.

1983 • 51 citations

Size of the plasma membrane H+-ATPase from Neurospora crassa determined by radiation inactivation and comparison with the sarcoplasmic reticulum Ca2+-ATPase from skeletal muscle.

1985 • 50 citations

The functional unit of polyenzymes. Determination by radiation inactivation.

1980 • 49 citations

Glucose transport carrier of human erythrocytes. Radiation-target size of glucose-sensitive cytochalasin B binding protein.

1980 • 49 citations

The Radiation Inactivation Method as a Tool to Study Structure‐Function Relationships in Proteins

1987 • 48 citations

Determination of the oligomeric structure of the Ca2+ pump protein in canine cardiac sarcoplasmic reticulum membranes using radiation inactivation analysis.

1983 • 46 citations

Radiation inactivation studies on the rabbit kidney sodium-dependent glucose transporter.

1985 • 46 citations

Transient complexes. A structural model for the activation of adenylate cyclase by hormone receptors (guanine nucleotides/irradiation inactivation)

1979 • 44 citations

The molecular form of acetylcholinesterase as determined by irradiation inactivation (Short Communication)

1974 • 44 citations

Glucose transport carrier of human erythrocytes. Radiation target size measurement based on flux inactivation.

1981 • 43 citations

Structural state of the Na+ /d-glucose cotransporter in calf kidney brush-border membranes Target size analysis of Na+-dependent phlorizin binding and Na+-dependent d-glucose transport

1984 • 43 citations

Nucleoside transport in human erythrocytes. Apparent molecular weight of the nitrobenzylthioinosine-binding complex estimated by radiation-inactivation analysis

1980 • 43 citations

Molecular properties of the apamin‐binding component of the Ca²⁺‐dependent K⁺ channel Radiation‐inactivation, affinity labelling and solubilization

1984 • 42 citations

Studies on (K+ + H+)-ATPase

1983 • 42 citations

Modification of subunit interaction in membrane‐bound acid β‐glucosidase from Gaucher disease

1983 • 41 citations

Minimal functional unit for transport and enzyme activities of (Na+ + K+)-ATPase as determined by radiation inactivation

1984 • 41 citations

Radiation inactivation of enzymes at low dose rates: Identical molecular weights of rat liver cytosolic and lysosomal neuraminidases

1982 • 41 citations

Molecular mechanism of the effects of guanine nucleotide and sulfhydryl reagent on muscarinic receptors in smooth muscles studied by radiation inactivation

1982 • 40 citations

Putative calcium channel molecular weight determination by target size analysis

1983 • 39 citations

Calmodulin-activated cyclic nucleotide phosphodiesterase from brain. Relationship of subunit structure to activity assessed by radiation inactivation.

1981 • 37 citations

Nucleoside transport in human erythrocytes

1984 • 35 citations

Temperature Dependence of Ionizing Radiation Effect on Dry Lysozyme and Ribonuclease

1966 • 35 citations

Unexpected findings from target analysis of immunoglobulin E and its receptor

1981 • 34 citations

Studies on the sialidoses. Properties of human leucocyte neuraminidases

1980 • 34 citations

Structure of the insulin receptor of the cultured human lymphoblastoid cell IM-9. Evidence suggesting that two subunits are required for insulin binding.

1982 • 34 citations

Target size analysis by radiation inactivation: A large capacity tube rack for irradiation in a Gammacell 220

1983 • 33 citations

Sequencing the Messenger

1973 • 33 citations

Calmodulin and the target size of the (Ca2+ + Mg2+)-ATPase of human red-cell ghosts

1984 • 31 citations

Radiation inactivation of assimilatory NADH:nitrate reductase from Chlorella. Catalytic and physical sizes of functional units.

1986 • 28 citations

Functional unit size of the neurotoxin receptors on the voltage-dependent sodium channel.

1985 • 28 citations

The molecular weight of the calcium-transport-ATPase of the human red blood cell determined by radiation inactivation

1983 • 27 citations

Glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides is a reliable internal standard for radiation-inactivation studies of membranes in the frozen state

1985 • 26 citations

Radiation inactivation of membrane proteins: Molecular weight estimates in situ and after Triton X-100 solubilization

1984 • 26 citations

Modulation of erythrocyte acetylcholinesterase by cardiolipin: Effect on subunit coupling revealed by irradiation inactivation

1980 • 25 citations

Radiation Inactivation Studies of the Benzodiazepine/γ‐Aminobutyric Acid/Chloride Ionophore Receptor Complex

1985 • 23 citations

Functional size of the human asialoglycoprotein receptor as determined by radiation inactivation.

1984 • 23 citations

The temperature dependence of radiation sensitivity of large molecules

1986 • 22 citations

Irradiation Inactivation Analysis of Acetylcholinesterase and the Effect of Buffer Salts

1982 • 22 citations

Sizes of opioid receptor types in rat brain membranes

1984 • 20 citations

Characterization of human placental neuraminidases. Stability, substrate specificity and molecular weight

1982 • 20 citations

The target sizes of the in situ and solubilized forms of human placental steroid sulfatase as measured by radiation inactivation☆

1983 • 20 citations

Functional lysosomal hydrolase size as determined by radiation inactivation analysis

1985 • 19 citations

Effects of mercaptans upon dihydropyridine binding sites on transverse tubules isolated from triads of rabbit skeletal muscle

1985 • 19 citations

Radiation inactivation of (Na+ + K+)-ATPase a small target size for the K+-occluding mechanism

1981 • 19 citations

Temperature Dependence of the Direct Action of Ionizing Radiation on Beef Heart Lactate Dehydrogenase: Enzyme Activity, Substrate and Coenzyme Affinities

1972 • 19 citations

Modifications of the molecular weight of membrane-bound nonspecific β-glucosidase in type 1 gaucher disease determined in situ by the radiation inactivation method

1984 • 18 citations

Structure of the thyrotropin receptor and thyroid adenylate cyclase system as determined by target analysis

1984 • 18 citations

Radiation inactivation of alpha1-adrenoceptors

1983 • 14 citations

Regulatory proteins (inhibitors or activators) affect estimates of Mr of enzymes and receptors by radiation inactivation. A theoretical model

1985 • 14 citations

The molecular size of multiple opiate receptors

1983 • 12 citations

Dry T 1 Bacteriophage in Measurement of Large Doses of Ionizing Radiation

1966 • 11 citations

Target sizes of human erythrocyte membrane Ca2+-ATPase and Mg2+-ATPase activities in the presence and absence of calmodulin

1985 • 11 citations

Target Molecular Weight of Mitochondrial ATPase*

1969 • 10 citations

Radiation Indication of Subunit Activity of Lactic Dehydrogenase

1965 • 10 citations

Simulation of an inhibitory equilibrium system. Aberrant proteinic target sizes as obtained by radiation inactivation

1984 • 9 citations

Target molecular weights for red cell band 3 stilbene and mercurial binding sites

1986 • 9 citations

Target size of the ryanodine receptor from junctional terminal cisternae of sarcoplasmic reticulum

1987 • 8 citations

Radiation Inactivation Analysis of Na,K-ATPase

1983 • 7 citations

Size changes of phosphodiesterase in bovine rod outer segments on illumination

1983 • 7 citations

Functional molecular size of trypsin inhibitors as determined by radiation inactivation analysis

1987 • 7 citations

Investigation of membrane-located receptors

1985 • 6 citations

Target size analysis of rhodopsin in retinal rod disk membranes

1984 • 5 citations

In situ determination of the molecular weight of hepatic γ-glutamyl transferase and γ-glutamyl hydrolase activities

1982 • 5 citations

Inactivation by Electron Radiation of the Capacity of Goldenrod Polysaccharide to Induce Vacuolization in Ascites Tumor Cells

1961 • 4 citations

Radiation inactivation of hepatic sulfite oxidase

1987 • 4 citations

Radiation Inactivation of Hamster Acrosin Reveals that the Biologically Active Unit is of Low Molecular Size1

1987 • 3 citations

Radiation inactivation analysis of the human erythrocyte system-L, amino acid transporter

1985 • 2 citations