Metabolic consequences of methylenecyclopropylglycine poisoning in rats

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

THE GLUCOSE FATTY-ACID CYCLE ITS ROLE IN INSULIN SENSITIVITY AND THE METABOLIC DISTURBANCES OF DIABETES MELLITUS

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Flavins and Flavoproteins

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1978 • 593 citations

Enzymes of fatty acid metabolism

1953 • 365 citations

Flavins and flavoproteins

1988 • 234 citations

The Presence of a New 3‐Oxoacyl‐CoA Thiolase in Rat Liver Peroxisomes

1980 • 196 citations

A simplified method for the preparation of 14C-labelled branched-chain α-oxo acids

1972 • 153 citations

Short-term regulation of liver metabolism

1982 • 142 citations

Inactivation of general acyl-CoA dehydrogenase from pig kidney by a metabolite of hypoglycin A.

1981 • 97 citations

A Novel mechanism for inhibition of β‐oxidation by methylenecyclopropylacetyl‐CoA, a metabolite of hypoglycin

1975 • 91 citations

α-(Methylenecyclopropyl)glycine from Litchi seeds

1962 • 91 citations

On the mechanisms of some pharmacological actions of the hypoglycaemic toxins hypoglycin and pent-4-enoic acid. A way out of the present confusion

1976 • 87 citations

Metabolic effects of hypoglycin and methylenecyclopropaneacetic acid

1966 • 81 citations

Mechanisms of the metabolic disturbances caused by hypoglycin and by pent-4-enoic acid. In vitro studies.

1978 • 80 citations

Biochemical effects of the hypoglycaemic compound pent-4-enoic acid and related non-hypoglycaemic fatty acids. Effects of the free acids and their carnitine esters on coenzyme A-dependent oxidations in rat liver mitochondria

1973 • 67 citations

Methylenecyclopropaneacetic acid, a metabolite of hypoglycin

1966 • 66 citations

Pathophysiology of peroxisomal beta-oxidation.

1989 • 62 citations

Measurement of the acyl-CoA intermediates of β-oxidation by h.p.l.c. with on-line radiochemical and photodiode-array detection. Application to the study of [U-14C]hexadecanoate oxidation by intact rat liver mitochondria

1989 • 56 citations

The existence of an inner-membrane-bound, long acyl-chain-specific 3-hydroxyacyl-CoA dehydrogenase in mammalian mitochondria

1982 • 56 citations

Mechanism of hypoglycaemic action of methylenecyclopropylglycine

1989 • 48 citations

4-Bromocrotonic acid, an effective inhibitor of fatty acid oxidation and ketone body degradation in rat heart mitochondria. On the rate-determining step of beta-oxidation and ketone body degradation in heart.

1982 • 45 citations

[48] 3-ketoacyl-CoA-thiolase with broad chain length specificity from pig heart muscle

1981 • 28 citations

Hypoglycin and Jamaican vomiting sickness.

1990 • 26 citations

Products and intermediates of the β-oxidation of [U-14C]hexadecanedionoyl-mono-CoA by rat liver peroxisomes and mitochondria

1991 • 21 citations

Protection of rats by clofibrate against the hypoglycaemic and toxic effects of hypoglycin and pent-4-enoate. An ultrastructural and biochemical study

1985 • 21 citations

A study of the metabolism of [U-14C]3-methyl-2-oxopentanoate by rat liver mitochondria using h.p.l.c. with continuous on-line monitoring of radioactive intact acyl-coenzyme A intermediates

1986 • 20 citations

The effects of hypoglycin on glucose metabolism in the rat. A kinetic study in vivo and [U-14C,2-3H]glucose

1978 • 19 citations

Some in vitro effects of hypoglycin on skin.

1967 • 16 citations

Organic aciduria in rats made resistant to hypoglycin toxicity by pretreatment with clofibrate

1987 • 14 citations

[48] 4-Pentenoic acid

1981 • 11 citations

Capillary gas chromatographic/mass spectrometric analysis of abnormal metabolites in hypoglycin-treated rat urine

1984 • 10 citations

[35] Pancreatic branched-chain-amino-acid aminotransferase

1988 • 9 citations

Mechanisms of enzyme inhibition by hypoglycin, methylenecyclopropylglycine and their metabolites.

1990 • 9 citations

[51] Enoyl-CoA hydratases from Clostridium acetobutylicum and Escherichia coli

1981 • 7 citations

A GENERAL METHOD FOR THE DETERMINATION OF TRANSAMINASE ACTIVITY: EFFECTS OF HYPOGLYCIN A

1963 • 7 citations

[42] 2-Bromooctanoate

1981 • 4 citations

Defective imino acid metabolism in hypoglycin-treated rats

1984 • 2 citations