Cultures of Mammary Epithelial Cells: Extracellular Matrix and Functional Differentiation

Role of cell shape in growth control

1978 • 2,434 citations

Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels

1982 • 2,259 citations

COLLAGEN SUBSTRATA FOR STUDIES ON CELL BEHAVIOR

1972 • 1,530 citations

Basement membrane complexes with biological activity

1986 • 1,489 citations

How does the extracellular matrix direct gene expression?

1982 • 1,475 citations

Multiple hormone interactions in the developmental biology of the mammary gland.

1980 • 866 citations

Primary culture of parenchymal liver cells on collagen membranes

1975 • 808 citations

Maintenance and induction of morphological differentiation in dissociated mammary epithelium on floating collagen membranes

1977 • 641 citations

Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells.

1987 • 591 citations

Transepithelial transport in cell culture.

1976 • 499 citations

Determination of cellular shape by the extracellular matrix and its correlation with the control of cellular growth.

1978 • 487 citations

Serum-free growth of human mammary epithelial cells: rapid clonal growth in defined medium and extended serial passage with pituitary extract.

1984 • 435 citations

Fibronectin modulation of cell shape and lipogenic gene expression in 3t3-adipocytes

1983 • 432 citations

The Growth of Cells on a Transparent Gel of Reconstituted Rat-Tail Collagen<xref ref-type="fn" rid="fn1">2</xref>

1956 • 422 citations

Protein synthesis requires cell-surface contact while nuclear events respond to cell shape in anchorage-dependent fibroblasts

1980 • 399 citations

The Mammary gland : development, regulation, and function

1987 • 396 citations

Epithelial mouse mammary cell line exhibiting normal morphogenesis in vivo and functional differentiation in vitro.

1984 • 336 citations

The Role of extracellular matrix in development

1984 • 334 citations

Growth of normal human mammary cells in culture

1980 • 316 citations

Modulation of secreted proteins of mouse mammary epithelial cells by the collagenous substrata.

1984 • 314 citations

Hormonal effects on intracellular and secreted casein in cultures of mouse mammary epithelial cells on floating collagen membranes.

1977 • 292 citations

Cell Shape and Phenotypic Expression in Chondrocytes

1983 • 287 citations

Sustained growth and three-dimensional organization of primary mammary tumor epithelial cells embedded in collagen gels.

1979 • 285 citations

Interaction of mouse mammary epithelial cells with collagen substrata: regulation of casein gene expression and secretion.

1985 • 279 citations

Extracellular matrix promotes mammary epithelial growth and differentiation in vitro.

1982 • 262 citations

Changes in cell shape correlate with collagenase gene expression in rabbit synovial fibroblasts.

1984 • 228 citations

Synthesis and extracellular deposition of fibronectin in chondrocyte cultures. Response to the removal of extracellular cartilage matrix.

1978 • 219 citations

Distribution of myoepithelial cells and basement membrane proteins in the resting, pregnant, lactating, and involuting rat mammary gland.

1982 • 213 citations

The Differentiated State of Normal and Malignant Cells or How to Define a “Normal” Cell in Culture

1981 • 208 citations

Role of basal lamina in neoplastic disorganization of tissue architecture.

1981 • 202 citations

Heparan sulfate proteoglycans from mouse mammary epithelial cells. A putative membrane proteoglycan associates quantitatively with lipid vesicles.

1983 • 187 citations

Cell and Muscle Motility

1982 • 185 citations

Substrate properties influencing ultrastructural differentiation of mammary epithelial cells in culture

1979 • 181 citations

Influence of geometry on control of cell growth

1975 • 169 citations

Differential response to growth factor by rat mammary epithelium plated on different collagen substrata in serum-free medium.

1981 • 167 citations

Basement membrane collagen requirements for attachment and growth of mammary epithelium

1979 • 166 citations

Sustained growth in primary culture of normal mammary epithelial cells embedded in collagen gels

1980 • 165 citations

Cell-cell interactions promote mammary epithelial cell differentiation.

1985 • 143 citations

An androgen-dependent mouse mammary tumor.

1965 • 139 citations

Stimulation of Mammary Epithelial Cell Growthin Vitro: Interaction of Epidermal Growth Factor and Mammogenic Hormones*

1985 • 138 citations

Mechanical stretching increases the number of epithelial cells synthesizing dna in culture

1984 • 132 citations

Connectin: cell surface protein that binds both laminin and actin.

1983 • 132 citations

Occluding junctions and cell behavior in primary cultures of normal and neoplastic mammary gland cells.

1975 • 129 citations

A simplified method for passage and long-term growth of human mammary epithelial cells

1986 • 123 citations

Growth of Mouse Mammary Glands in vivo after Monolayer Culture

1965 • 123 citations

Replication of Mammary Tumor Virus in Tumor Cell Cultures: Dependence on Hormone-Induced Cellular Organization<xref ref-type="fn" rid="FN2">2</xref>

1971 • 120 citations

Serum-free growth of normal and tumor mouse mammary epithelial cells in primary culture.

1982 • 118 citations

Type I collagen reduces the degradation of basal lamina proteoglycan by mammary epithelial cells.

1981 • 114 citations

The influence of cell shape on the induction of functional differentiation in mouse mammary cells in vitro

1981 • 113 citations

Calcium regulation of normal human mammary epithelial cell growth in culture

1984 • 113 citations

Hormonal requirements for basement membrane collagen deposition by cultured rat mammary epithelium.

1979 • 110 citations

Effect of cell shape change on the function and differentiation of rabbit mammary cells in culture

1983 • 107 citations

Cultivation and behavior in vitro of the normal mammary epithelium of the adult mouse

1957 • 103 citations

Gene Expression During Normal and Malignant Differentiation

1985 • 101 citations

A method for the continuous cultivation of mammary epithelium

1971 • 99 citations

Secretory function of lactating mouse mammary epithelial cells cultured on collagen gels

1980 • 99 citations

Heparin regulates the collagen phenotype of vascular smooth muscle cells: induced synthesis of an Mr 60,000 collagen.

1985 • 98 citations

Removal of basement membrane in the involuting breast.

1976 • 96 citations

Interactions of rat hepatocytes with type IV collagen, fibronectin and laminin matrices. Distinct matrix-controlled modes of attachment and spreading.

1986 • 92 citations

Characterization of a myoepithelial cell line derived from a neonatal rat mammary gland.

1981 • 90 citations

Collagenous substrata regulate the nature and distribution of glycosaminoglycans produced by differentiated cultures of mouse mammary epithelial cells

1985 • 88 citations

Cell proliferation and milk protein gene expression in rabbit mammary cell cultures

1983 • 82 citations

Mammary gland morphogenesis in vitro: Formation of branched tubules in collagen gels by a cloned rat mammary cell line

1982 • 81 citations

3T3-L1 Adipocytes promote the growth of mammary epithelium

1984 • 81 citations

Human mammary gland morphogenesis in vitro: The growth and differentiation of normal breast epithelium in collagen gel cultures defined by electron microscopy, monoclonal antibodies, and autoradiography

1983 • 80 citations

Transferrin mRNA level in the mouse mammary gland is regulated by pregnancy and extracellular matrix.

1987 • 79 citations

Regulation of growth and differentiation of a rat hepatoma cell line by the synergistic interactions of hormones and collagenous substrata.

1983 • 79 citations

Functional biochemical changes in bovine mammary cell cultures

1961 • 79 citations

Growth of diploid cells from breast cancers

1985 • 79 citations

Influence of Seeding Density on Multicellular Organization and Nuclear Events in Cultures of Normal and Neoplastic Mouse Mammary Epithelium2

1974 • 76 citations

Primary Culture of Human Mammary Epithelial Cells Embedded in Collagen Gels<xref ref-type="fn" rid="fn2">2</xref>

1980 • 73 citations

Preservation of defined phenotypic traits in short-term cultured human breast carcinoma derived epithelial cells.

1987 • 69 citations

Cell shape and hexose transport in normal and virus‐transformed cells in culture

1977 • 64 citations

The biology of breast cancer at the cellular level

1984 • 64 citations

Transferrin is a major mouse milk protein and is synthesized by mammary epithelial cells

1987 • 62 citations

Casein gene expression in mouse mammary epithelial cell lines: Dependence upon extracellular matrix and cell type

1987 • 61 citations

Comparison of the growth of normal and neoplastic mouse mammary cells on plastic, on collagen gels and in collagen gels

1983 • 60 citations

Effect of exogenous extracellular matrices on proteoglycan synthesis by cultured rabbit costal chondrocytes.

1985 • 57 citations

Differential response of normal rat mammary epithelial cells to mammogenic hormones and EGF

1985 • 56 citations

Casein production during differentiation of mammary epithelial cells in collagen gel culture

1985 • 54 citations

Multihormonal Regulation of Milk Protein Gene Expression

1986 • 52 citations

Co-expression of differentiation markers in hybrids between friend cells and lymphoid cells and the influence of the cell shape

1980 • 48 citations

Variability in surface antigen expression of human breast epithelial cells cultured from normal breast, normal tissue peripheral to breast carcinomas, and breast carcinomas.

1984 • 48 citations

Glucose metabolite patterns as markers of functional differentiation in freshly isolated and cultured mouse mammary epithelial cells

1981 • 45 citations

Significance of three-dimensional growth patterns of mammary tissues in collagen gels

1983 • 45 citations

Comparison of collagen gels and mammary extracellular matrix as substrata for study of terminal differentiation in rabbit mammary epithelial cells

1984 • 42 citations

Comparative maintenance of function in dispersed cell and organ cultures of bovine mammary tissue

1970 • 42 citations

Distribution of entactin in the basement membrane of the rat mammary gland

1984 • 41 citations

Cultureof bovine mammary epithelial cells on collagen gels

1982 • 39 citations

Synthesis of basement membrane proteins by rat mammary epithelial cells

1983 • 38 citations

Growth and differentiation of mammary epithelial cells in culture

1987 • 37 citations

Serum-free primary culture of human normal mammary epithelial cells in collagen gel matrix

1982 • 35 citations

TPA induces simultaneous alterations in the synthesis and organization of vimentin

1983 • 33 citations

Changes in microfilament and focal adhesion distribution with loss of androgen responsiveness in cultured mammary tumor cells.

1981 • 32 citations

Hormone induction of specific protein synthesis in midpregnant mouse mammary cell culture

1976 • 28 citations

Different mitogenic and phenotypic responses of human breast epithelial cells grown in two versus three dimensions

1986 • 27 citations

Effects of endocrine regulation of growth of a mouse mammary tumor on its sensitivity to chemotherapy.

1984 • 26 citations

Expression of epithelial antigens in primary cultures of normal human breast analysed with monoclonal antibodies

1984 • 25 citations

Collagen gel culture system and analysis of estrogen effects on mammary carcinogenesis

1984 • 25 citations

Interrelationship of glycogen metabolism and lactose synthesis in mammary epithelial cells of mice

1980 • 22 citations

Effect of estradiol on nonmalignant human mammary cells in primary culture.

1984 • 22 citations

Effects of defined medium, fetal bovine serum, and human serum on growth and chemosensitivities of human breast cancer cells in primary culture: Inference for in vitro assays

1987 • 22 citations

Characterization of the intermediate filament proteins of Murine Mammary Gland epithelial cells

1986 • 17 citations

Benign prostatic hyperplasia

1985 • 15 citations

Ultrastructural features of bovine mammary epithelial cells grown on collagen gels

1985 • 13 citations

Antiandrogen effects on androgen-responsive mammary tumour cells in culture

1981 • 11 citations

Phenotypic stability of mouse mammary tumor cells cultured on collagen gels

1985 • 9 citations

Permissive effect of the extracellular matrix on attachment and maintenence of human breast carcinoma cells in vitro

1982 • 7 citations