Zonation of cytochrome P450 enzyme expression in rat liver

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A simple, rapid, and sensitive DNA assay procedure

1980 • 5,006 citations

The Liver: Biology and Pathobiology.

1983 • 1,628 citations

The Liver: Biology and Pathobiology

1995 • 629 citations

Metabolic zonation of the liver: Regulation and implications for liver function

1992 • 558 citations

Molecular genetics of the P-450 superfamily

1990 • 496 citations

Regulation of rat growth hormone receptor gene expression

1989 • 446 citations

The growth hormone-binding protein in rat serum is an alternatively spliced form of the rat growth hormone receptor.

1989 • 399 citations

Ethanol-, fasting-, and aceton-inducible cytochromes P-450 in rat liver: regulation and characteristics of enzymes belonging to the IIB and IIE gene subfamilies

1988 • 316 citations

Hormonal and developmental regulation of expression of the hepatic microsomal steroid 16 alpha-hydroxylase cytochrome P-450 apoprotein in the rat.

1985 • 261 citations

Centrilobular expression of ethanol-inducible cytochrome P-450 (IIE1) in rat liver

1988 • 178 citations

Suppression of levels of phenobarbital-inducible rat liver cytochrome P-450 by pituitary hormone.

1987 • 177 citations

Cytochrome P-450 distribution in rat liver and the effect of sodium phenobarbitone administration

1978 • 153 citations

An immunohistochemical study on the localization and distributions of phenobarbital- and 3-methylcholanthrene-inducible cytochromes P-450 within the livers of untreated rats.

1981 • 150 citations

Dose-response relationships for chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in a rat tumor promotion model: quantification and immunolocalization of CYP1A1 and CYP1A2 in the liver.

1992 • 146 citations

Adult male-specific and neonatally programmed rat hepatic P-450 forms RLM2 and 2a are not dependent on pulsatile plasma growth hormone for expression.

1988 • 138 citations

Nuclear translocation and anchorage of the growth hormone receptor.

1994 • 131 citations

Zonation of cytochrome P450 isozyme expression and induction in rat liver

1992 • 120 citations

Hypothalamo-Pituitary Regulation of Cytochrome P-450_15βApoprotein Levels in Rat Liver*

1985 • 97 citations

Female-Predominant Rat Hepatic P-450 Forms j (IIE1) and 3 (IIA1) Are under Hormonal Regulatory Controls Distinct from Those of the Sex-Specific P-450 Forms*

1989 • 97 citations

Differential regulation by growth hormone (GH) of insulin-like growth factor I and GH receptor/binding protein gene expression in rat liver.

1992 • 77 citations

Rapid analysis and purification of polymerase chain reaction products by high-performance liquid chromatography.

1990 • 72 citations

One class of growth hormone (GH) receptor and binding protein messenger ribonucleic acid in rat liver, GHR1, is sexually dimorphic and regulated by GH.

1995 • 70 citations

Polypeptide hormone degradation and receptor regulation are coupled to ligand internalization. A direct biochemical and morphologic demonstration.

1981 • 67 citations

A Role for Protein Kinases in the Growth Hormone Regulation of Cytochrome P4502C12 and Insulin-Like Growth Factor-I Messenger RNA Expression in Primary Adult Rat Hepatocytes

1991 • 60 citations

Dual-digitonin-pulse perfusion. Concurrent sampling of periportal and perivenous cytosol of rat liver for determination of metabolites and enzyme activities

1987 • 60 citations

Constitutive expression and hormonal regulation of male sexually differentiated cytochromes P450 in primary cultured rat hepatocytes

1992 • 59 citations

Difference in the susceptibility of two phenobarbital-inducible forms, P450IIB1 and P450IIB2, to thyroid hormone- and growth hormone-induced suppression in rat liver: phenobarbital-inducible P450IIB2 suppression by thyroid hormone acting directly, but not through the pituitary system.

1991 • 58 citations

Hormonal regulation of the zonated expression of cytochrome P-450 3A in rat liver

1995 • 55 citations

Hormonal Regulation of Male-specific Rat Hepatic Cytochrome P-450g (P-450IIC13) by Androgens and the Pituitary

1989 • 55 citations

Thyroid hormone suppression of hepatic levels of phenobarbital-inducible P-450b AND P-450e and other neonatal P-450S in hypophysectomized rats

1989 • 44 citations

Pretranslational induction of cytochrome P4501A enzymes by β-naphthoflavone and 3-methylcholanthrene occurs in different liver zones

1994 • 37 citations

Effects of growth hormone on cytochrome P-450j

1988 • 34 citations

Hormonal Regulation of Cytochrome P450 in Rat Liver

1993 • 34 citations

Growth hormone mediates zone‐specific gene expression in liver

1993 • 25 citations

A rapid method to study heterogeneous gene expression in liver by direct assay of messenger RNA from periportal and perivenous cell lysates

1993 • 24 citations