Cytoplasmic calcium transients due to single action potentials and voltage-clamp depolarizations in mouse pancreatic B-cells.

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

2012 • 8,865 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

2014 • 5,592 citations

Three types of neuronal calcium channel with different calcium agonist sensitivity

1985 • 2,212 citations

Muscarinic activation of ionic currents measured by a new whole-cell recording method.

1988 • 1,777 citations

Electrophysiology of the pancreatic β-cell

1989 • 1,123 citations

Regulation of insulin release by calcium.

1981 • 866 citations

Calcium gradients and buffers in bovine chromaffin cells.

1992 • 746 citations

Calcium requirements for secretion in bovine chromaffin cells.

1992 • 416 citations

Calcium and delayed potassium currents in mouse pancreatic beta‐cells under voltage‐clamp conditions.

1986 • 370 citations

Widespread synchronous [Ca2+]i oscillations due to bursting electrical activity in single pancreatic islets

1991 • 350 citations

Significance of ionic fluxes and changes in membrane potential for stimulus-secretion coupling in pancreatic B-cells

1984 • 324 citations

Calcium domains associated with individual channels can account for anomalous voltage relations of CA-dependent responses

1984 • 324 citations

Single islet beta-cell stimulation by nutrients: relationship between pyridine nucleotides, cytosolic Ca2+ and secretion.

1990 • 265 citations

Electrophysiology of the pancreas.

1987 • 259 citations

Calmodulin Activation of Adenylate Cyclase in Pancreatic Islets

1979 • 234 citations

Cytosolic Ca2+, exocytosis, and endocytosis in single melanotrophs of the rat pituitary

1990 • 208 citations

Properties and calcium‐dependent inactivation of calcium currents in cultured mouse pancreatic B‐cells.

1988 • 180 citations

Inhibition of ATP-regulated K+ channels precedes depolarization-induced increase in cytoplasmic free Ca2+ concentration in pancreatic beta-cells.

1987 • 173 citations

Potassium selective ion channels in insulin-secreting cells: physiology, pharmacology and their role in stimulus-secretion coupling

1991 • 157 citations

Presence and possible role of calcium-dependent regulator (calmodulin) in rat islets of langerhans

1979 • 142 citations

Modulation of dihydropyridine-sensitive Ca2+ channels by glucose metabolism in mouse pancreatic β -cells

1989 • 142 citations

The kinetics of calcium binding to fura‐2 and indo‐1

1987 • 130 citations

Acetylcholine-evoked increase in the cytoplasmic Ca2+ concentration and Ca2+ extrusion measured simultaneously in single mouse pancreatic acinar cells.

1992 • 125 citations

Mouse pancreatic beta‐cells: tetraethylammonium blockage of the potassium permeability increase induced by depolarization.

1979 • 119 citations

Ca2+-activated ATPase and ATP-dependent calmodulin-stimulated Ca2+ transport in islet cell plasma membrane

1980 • 110 citations

Single Ca channel currents in mouse pancreatic B-cells

1988 • 102 citations

Calcium current inactivation in insulin-secreting cells is mediated by calcium influx and membrane depolarization

1989 • 87 citations

Characterization of the inositol 1,4,5-trisphosphate-induced Ca2+ release in pancreatic β-cells

1987 • 86 citations

Delayed rectifying and calcium-activated K+ channels and their significance for action potential repolarization in mouse pancreatic beta-cells.

1990 • 84 citations

Pancreatic B cells are bursting, but how?

1991 • 77 citations

Cyclic AMP as a determinant for glucose induction of fast Ca2+ oscillations in isolated pancreatic beta-cells

1991 • 75 citations

Evidence for two calcium currents in insulin-secreting cells

1988 • 66 citations

Single‐channel Ba²⁺ currents in insulin‐secreting cells are activated by glyceraldehyde stimulation

1988 • 56 citations

Two types of Ca channel in rat pancreatic ?-cells

1990 • 53 citations

Inactivation kinetics and pharmacology distinguish two calcium currents in mouse pancreatic B-cells

1991 • 53 citations

Calmodulin-activated protein kinase activity in rat pancreatic islet cell membranes

1982 • 52 citations

Effects of the calcium channel agonist, BAY K 8644, on electrical activity in mouse pancreatic B-cells

1985 • 51 citations

Voltage‐gated and agonist‐mediated rises in intracellular Ca2+ in rat clonal pituitary cells (GH3) held under voltage clamp.

1989 • 50 citations

Alterations in [Ca2+]i mediated by sodium‐calcium exchange in smooth muscle cells isolated from the guinea‐pig ureter.

1989 • 43 citations

Glucose-induced increase in cytoplasmic pH in pancreatic beta-cells is mediated by Na+/H+ exchange, an effect not dependent on protein kinase C.

1991 • 41 citations

Single-channel recordings of two types of calcium channels in rat pancreatic beta-cells

1990 • 38 citations

Effects of sodium on beta-cell electrical activity

1982 • 38 citations

Characterization of the process of sodium-calcium exchange in pancreatic islet cells

1990 • 31 citations

Effects of acute sodium omission on insulin release, ionic flux and membrane potential in mouse pancreatic B-cells

1988 • 24 citations