Nonimmunologic Mechanisms of Glomerular Injury

Hyperfiltration in remnant nephrons: a potentially adverse response to renal ablation

1981 • 1,664 citations

Renal Syndromes Associated with Nonsteroidal Antiinflammatory Drugs

1984 • 1,098 citations

Therapeutic advantage of converting enzyme inhibitors in arresting progressive renal disease associated with systemic hypertension in the rat.

1986 • 1,071 citations

Control of glomerular hypertension limits glomerular injury in rats with reduced renal mass.

1985 • 931 citations

Glomerular hemodynamics in experimental diabetes mellitus

1981 • 785 citations

Nephron adaptation to renal injury or ablation

1985 • 633 citations

A progressive glomerulosclerosis occurring in partial five-sixths nephrectomized rats.

1975 • 449 citations

Treatment of hyperlipidemia reduces glomerular injury in obese Zucker rats

1988 • 413 citations

Nutritional Influences on Aging of Fischer 344 Rats: II. Pathology

1985 • 356 citations

Altered glomerular permselectivity and progressive sclerosis following extreme ablation of renal mass

1982 • 355 citations

Progression of Nephropathy in Long-Term Diabetics with Proteinuria and Effect of Initial Anti-Hypertensive Treatment

1976 • 352 citations

The biology of renal hypertrophy

1986 • 350 citations

Chronic effects of dietary protein in the rat with intact and reduced renal mass

1986 • 337 citations

Hypertension and proteinuria: Long-term sequelae of uninephrectomy in humans

1984 • 324 citations

Glomerular hypertrophy and epithelial cell injury modulate progressive glomerulosclerosis in the rat.

1989 • 305 citations

Progressive glomerulosclerosis develops in transgenic mice chronically expressing growth hormone and growth hormone releasing factor but not in those expressing insulinlike growth factor-1.

1988 • 304 citations

Pharmacologic treatment of hyperlipidemia reduces glomerular injury in rat 5/6 nephrectomy model of chronic renal failure.

1988 • 294 citations

EXPERIMENTAL RENAL INSUFFICIENCY PRODUCED BY PARTIAL NEPHRECTOMY

1932 • 280 citations

Hemodynamic basis for glomerular injury in rats with desoxycorticosterone-salt hypertension.

1984 • 277 citations

Reversing glomerular hypertension stabilizes established glomerular injury

1987 • 269 citations

Pathogenesis of the glomerulopathy associated with renal infarction in rats

1976 • 267 citations

RENAL CHANGES IN MALIGNANT HYPERTENSION

1939 • 249 citations

RECYCLING DISPOSABLES

1974 • 240 citations

Focal and segmental glomerulosclerosis and porteinuria associated with unilateral renal agenesis.

1982 • 236 citations

Mechanisms of action of various hormones and vasoactive substances on glomerular ultrafiltration in the rat

1981 • 230 citations

Mesangial lesions and focal glomerular sclerosis in the aging rat.

1975 • 227 citations

Contribution of the renin-angiotensin system to the control of intrarenal hemodynamics

1984 • 216 citations

Selectivity of renal injury and proteinuria in the spontaneously hypertensive rat

1977 • 204 citations

Inhibition of thromboxane synthesis ameliorates the progressive kidney disease of rats with subtotal renal ablation.

1985 • 189 citations

Heparin: An Old Drug with a New Paradigm

1979 • 188 citations

Renal Disease in Patients With Massive Obesity

1986 • 179 citations

Renal and nephron hemodynamics in spontaneously hypertensive rats

1979 • 177 citations

LONG-TERM RENAL FUNCTION IN KIDNEY DONORS

1983 • 173 citations

Renal autoregulation and vulnerability to hypertensive injury in remnant kidney

1987 • 171 citations

Age‐related nephropathy in laboratory rats

1988 • 168 citations

Focal glomerulosclerosis in patients with unilateral nephrectomy

1983 • 164 citations

EXPERIMENTAL RENAL INSUFFICIENCY PRODUCED BY PARTIAL NEPHRECTOMY

1939 • 159 citations

Heparin and glomerular epithelial cell-secreted heparin-like species inhibit mesangial-cell proliferation.

1985 • 156 citations

Spontaneous glomerular sclerosis in aging Sprague-Dawley rats. I. Lesions associated with mesangial IgM deposits.

1976 • 153 citations

THE VICIOUS CIRCLE IN CHRONIC BRIGHT'S DISEASE. EXPERIMENTAL EVIDENCE FROM THE HYPERTENSIVE RAT

1941 • 150 citations

Dietary protein restriction in established renal injury in the rat. Selective role of glomerular capillary pressure in progressive glomerular dysfunction.

1986 • 146 citations

Role of dietary factors in the progression of chronic renal disease

1983 • 145 citations

Relative Increase in Insulin-Like Growth Factor I Messenger Ribonucleic Acid Levels in Compensatory Renal Hypertrophy*

1987 • 140 citations

Phosphate depletion arrests progression of chronic renal failure independent of protein intake

1986 • 138 citations

Influence of the Restriction of Individual Dietary Components on Longevity And Age-Related Disease of Fischer Rats: The Fat Component and the Mineral Component

1988 • 132 citations

The Progressive nature of renal disease

1986 • 131 citations

Experimentally induced chronic renal insufficiency in the rat.

1962 • 129 citations

The Risks of Unilateral Nephrectomy: Status of Kidney Donors 10 to 20 Years Postoperatively

1985 • 126 citations

Impact of renal donation. Long-term clinical and biochemical follow-up of living donors in a single center

1985 • 123 citations

Focal Sclerosis of Hypertrophied Glomeruli in Solitary Functioning Kidneys of Humans

1985 • 117 citations

Glomerulosclerosis and renal cysts in mice transgenic for the early region of SV40

1987 • 114 citations

Effects of genetic obesity on renal structure and function in the Zucker rat. II. Micropuncture studies.

1985 • 114 citations

RENAL FUNCTION IN CHRONIC RENAL DISEASE

1965 • 112 citations

Therapeutic implications of hypertension-induced glomerular injury: Comparison of enalapril and a combination of hydralazine, reserpine, and hydrochlorothiazide in an experimental model

1985 • 111 citations

Focal Segmental Glomerulosclerosis and Progressive Renal Failure Associated with a Unilateral Kidney

1984 • 108 citations

Role of heparin as a protective agent following reduction of renal mass

1984 • 107 citations

Regulation of Glomerular Capillary Pressure and Filtration Rate in Young Kyoto Hypertensive Rats

1979 • 105 citations

Serial micropuncture analysis of single nephron function in subtotal renal ablation

1988 • 105 citations

Focal and segmental glomerular sclerosis in reflux nephropathy

1980 • 98 citations

The causation of acute arterial necrosis in hypertensive disease

1948 • 95 citations

Angiotensin II effects on microvascular diameters of in vitro blood-perfused juxtamedullary nephrons

1986 • 89 citations

Long-term renal responses to high dietary protein in dogs with 75% nephrectomy

1986 • 88 citations

Converting enzyme inhibitor therapy limits progressive glomerular injury in rats with renal insufficiency

1985 • 87 citations

Mechanism of exaggerated diuresis in spontaneously hypertensive rats

1978 • 87 citations

The Hypertensive Vascular Crisis. An Experimental Study.

1970 • 84 citations

Dietary protein increases plasma renin and reduces pressor reactivity to angiotensin II

1986 • 82 citations

Analysis of renal structural and functional features in two rat strains with a different susceptibility to glomerular sclerosis.

1986 • 81 citations

Effects of dietary fish oil on renal insufficiency in rats with subtotal nephrectomy

1987 • 79 citations

Glomerular hyalinosis and its relation to hyperfiltration.

1985 • 79 citations

Relation of glomerular injury to preglomerular resistance in experimental hypertension

1986 • 74 citations

Age-dependent glomerulosclerosis and proteinuria occurring in rats of the Milan normotensive strain and not in rats of the Milan hypertensive strain.

1986 • 74 citations

Changes of hemodynamics and glomerular ultrafiltration in renal hypertension of rats

1979 • 74 citations

A stereologic study of glomerular hypertrophy in the subtotally nephrectomized rat.

1978 • 73 citations

The results following partial Nephrectomy and the influence of the Kidney on Metabolism1

1899 • 72 citations

Hypertension and necrotizing arteritis in the rat following renal infarction.

1946 • 72 citations

Steroid-induced hypertension in the rat. A microangiographic and histologic study on the pathogenesis of hypertensive vascular and glomerular lesions.

1968 • 70 citations

Effects of a dietary prostaglandin precursor on the progression of experimentally induced chronic renal failure.

1982 • 70 citations

Protein-induced glomerular hyperfiltration: Role of hormonal factors

1988 • 70 citations

Glomerular hypertension and injury in desoxycorticosterone–salt rats on antihypertensive therapy

1987 • 69 citations

Natural history and pathogenesis of renal ablation hypertension.

1960 • 66 citations

Feedback mediation of SNGFR autoregulation in hydropenic and DOCA- and salt-loaded rats

1979 • 64 citations

THE FUNCTIONAL CAPACITY OF HYPERTROPHIED NEPHRONS

1966 • 61 citations

Congenital Bilateral Oligonephronic Renal Hypoplasia with Hypertrophy of Nephrons (Oligoméganéphronie): Studies by Microdissection

1969 • 61 citations

The significance of focal segmental glomerulosclerosis in oligomeganephronia.

1984 • 58 citations

Characterization of age-associated kidney disease in Wistar rats

1975 • 57 citations

Prostaglandin and Thromboxane Formation in Glomeruli from Rats with Reduced Renal Mass

1986 • 56 citations

Regulatory role of prostanoids in glomerular microcirculation of remnant nephrons

1987 • 56 citations

Morphometric aspects of reflux nephropathy

1987 • 53 citations

Beneficial effects of polyunsaturated fatty acids in partially nephrectomized rats

1986 • 51 citations

Effect of dietary lipids on renal function in rats with subtotal nephrectomy

1987 • 50 citations

THE EFFECT OF EXPERIMENTAL REDUCTION OF KIDNEY SUBSTANCE UPON THE PARATHYROID GLANDS AND SKELETAL TISSUE

1936 • 49 citations

Preventing the progression of human renal disease: Have rational therapeutic principles emerged?

1988 • 48 citations

Selective deep nephron hyperfiltration in uninephrectomized spontaneously hypertensive rats

1983 • 48 citations

Glomerular function and morphology after renal mass reduction in dogs.

1987 • 46 citations

Diabetic glomerulopathy in man and experimental animal models.

1984 • 45 citations

EXPERIMENTAL RENAL INSUFFICIENCY PRODUCED BY PARTIAL NEPHRECTOMY

1936 • 41 citations

Dietary protein restriction in established renal injury in the rat: selective role of glomerular capillary pressure in progressive glomerular dysfunction. J Clin Invest 78:1199-1205

1986 • 41 citations

Development of renal lesions in dogs after 11/12 reduction of renal mass. Influences of dietary protein intake.

1988 • 40 citations

Acute adaptative changes to unilateral nephrectomy in humans

1987 • 39 citations

Glomerular and vascular lesions in chronic atrophic pyelonephritis and reflux nephropathy.

1975 • 39 citations

The effects of heparin treatment on hypertension and vascular lesions in stroke-prone spontaneously hypertensive rats.

1981 • 37 citations

Beneficial Effect of Low Phosphorus Diet in Uraemic Rats: A Reappraisal

1982 • 34 citations

Steroid-induced hypertension in the rat. A study of the effects of renal artery constriction on hypertension caused by deoxycorticosterone.

1967 • 33 citations

THE REGULATION OF RENAL ACTIVITY

1924 • 33 citations

THE REGULATION OF RENAL ACTIVITY

1918 • 30 citations

Hypertension with Arteriolar and Glomerular Changes in the Albino Rat Following Subtotal Nephrectomy

1933 • 29 citations

Vascular fibrinoid necrosis in hypertension

1959 • 28 citations

The pathogenesis of the glomerular changes in steroid-induced hypertension in the rat.

1969 • 28 citations

A thromboxane synthetase antagonist ameliorates progressive renal disease of Dahl-S rats

1988 • 27 citations

Quantitative Morphological Studies of Aging Changes in the Kidney of the Lewis Rat

1984 • 21 citations

Tubuloglomerular feedback and glomerular morphology in Goldblatt hypertensive rats on varying protein diets

1986 • 21 citations

Factors that may retard the progression of renal disease.

1987 • 21 citations

Studies on the Pathogenesis of Hypertensive Vascular Disease

1970 • 20 citations

Inhibition of compensatory renal growth by indomethacin

1986 • 18 citations

Nephrotoxic serum nephritis with hypertension: Perfusion pressure and permselectivity

1988 • 12 citations

Eicosanoids: Biosynthesis and Function in the Glomerulus

1987 • 11 citations

Clip-ablation. A model of experimental hypertension in the rat.

1987 • 7 citations

Dietary protein restriction reduces glomerular volume and proteinuria in rats with established adriamycin nephrosis

1988 • 5 citations

Histomorphometric Study of the Enhancement of Renal Compensatory Hypertrophy by ACTH in the Rat

1984 • 1 citations