Back to search

The Protein Products of the Murine 17th Chromosome: Genetics and Structure

Data up to Jan 2025

Published1978
Citations136
References157

Total Citations Per Year

Abstract

References (157)

Rapid Isolation of Antigens from Cells with A Staphylococcal Protein A-Antibody Adsorbent: Parameters of the Interaction of Antibody-Antigen Complexes with Protein A

1975 • 3,054 citations

Progress in Clinical and Biological Research

1979 • 1,317 citations

Biology of the Mouse Histocompatibility-2 Complex

1975 • 1,145 citations

The H-2 Major Histocompatibility Complex and the/Immune Response Region: Genetic Variation, Function, and Organization

1975 • 774 citations

Isolation and Properties of a Low Molecular Weight β2-Globulin Occurring in Human Biological Fluids

1968 • 733 citations

Progress in Clinical and Biological Research

1984 • 554 citations

Cell-mediated lympholysis of trinitrophenyl-modified autologous lymphocytes. Effector cell specificity to modified cell surface components controlled by H-2K and H-2D serological regions of the murine major histocompatibility complex.

1975 • 381 citations

The role of macrophages in the generation of T-helper cells. II. The genetic control of the macrophage-T-cell interaction for helper cell induction with soluble antigens.

1975 • 364 citations

A new I subregion (I-J) marked by a locus (Ia-4) controlling surface determinants on suppressor T lymphocytes.

1976 • 353 citations

Surface Antigens Common to Mouse Cleavage Embryos and Primitive Teratocarcinoma Cells in Culture

1973 • 330 citations

ANTIGENIC MODULATION

1968 • 322 citations

The genetic and antigenic basis of tumour transplantation

1937 • 313 citations

Development of the short‐tailed mutant in the house mouse

1935 • 305 citations

New Lymphocyte Antigen System ( Lna ) Controlled by the Ir Region of the Mouse H-2 Complex

1973 • 282 citations

A MOUSE B-CELL ALLOANTIGEN DETERMINED BY GENE(S) LINKED TO THE MAJOR HISTOCOMPATIBILITY COMPLEX

1973 • 274 citations

The β2-microglobulin gene is on chromosome 15 and not in the HL-A region

1975 • 274 citations

Mouse Teratocarcinoma and Embryonic Antigens

1977 • 270 citations

The H-2 locus of the mouse: observations and speculations concerning its comparative genetics and its polymorphism.

1968 • 238 citations

EVIDENCE FOR THE EXPRESSION OF Ia (H-2-ASSOCIATED) ANTIGENS ON THYMUS-DERIVED LYMPHOCYTES

1974 • 233 citations

ACTIVATION OF T AND B LYMPHOCYTES IN VITRO

1974 • 231 citations

Antigenic Properties of Experimental Leukemias. I. Serological Studies <italic>In Vitro</italic> With Spontaneous and Radiation-Induced Leuke-mias<xref ref-type="fn" rid="FN2">2</xref>

1963 • 225 citations

THE ROLE OF PRODUCTS OF THE HISTOCOMPATIBILITY GENE COMPLEX IN IMMUNE RESPONSES

1975 • 223 citations

Production of Large Amounts of Antibodies in Individual Mice

1976 • 212 citations

Tissue distribution of ia antigens: Ia on spermatozoa, macrophages, and epidermal cells

1974 • 210 citations

Hypervariable Regions, Idiotypy, and the Antibody-Combining Site

1975 • 201 citations

The Histocompatibility-Linked Immune Response Genes

1975 • 186 citations

HISTOCOMPATIBILITY-LINKED IMMUNE RESPONSE GENE FUNCTION IN GUINEA PIGS

1972 • 186 citations

Serological Identification of an Ir-Region Product

1973 • 182 citations

GENETIC CONTROL OF THE ANTIBODY RESPONSE

1967 • 178 citations

EVIDENCE FOR IDENTITY OR CLOSE ASSOCIATION OF THE Fc RECEPTOR OF B LYMPHOCYTES AND ALLOANTIGENS DETERMINED BY THE Ir REGION OF THE H-2 COMPLEX

1974 • 173 citations

Antigen-specific T-cell factor in cell cooperation. Mapping within the I region of the H-2 complex and ability to cooperate across allogeneic barriers.

1975 • 172 citations

Structure of HLA antigens: amino-acid and carbohydrate compositions and NH2-terminal sequences of four antigen preparations.

1976 • 168 citations

TheTla region of the mouse: Identification of a new serologically defined locus,Qa-2

1976 • 168 citations

Modification of the antigenic structure of the cell membrane by thymus-leukemia (TL) antibody.

1967 • 160 citations

T lymphocyte-enriched murine peritoneal exudate cells. III. Inhibition of antigen-induced T lymphocyte Proliferation with anti-Ia antisera.

1976 • 158 citations

A new serologically defined locus,Qa-1, in theTla-region of the mouse

1976 • 156 citations

Molecular similarities between the Qa-2 alloantigen and other gene products of the 17th chromosome of the mouse.

1977 • 146 citations

Isolation of H-2 Alloantigens Solubilized by the Detergent NP-40

1971 • 146 citations

Biochemical properties and immunochemical-genetic relationships of mouse H-2 alloantigens

1974 • 143 citations

ACTIVATION OF T AND B LYMPHOCYTES IN VITRO

1974 • 142 citations

Membrane Molecules Determined by the H-2 Associated Immune Response Region: Isolation and Some Properties

1974 • 134 citations

Selective expression of H-2 (i-region) loci controlling determinants on helper and suppressor T lymphocytes.

1976 • 131 citations

Notable diversity in peptide composition of murine H-2K and H-2D alloantigens

1974 • 129 citations

Detergent-solubilised H-2 alloantigen is associated with a small molecular weight polypeptide

1974 • 129 citations

Subunit structure, cell surface orientation, and partial amino-acid sequences of murine histocompatibility antigens.

1976 • 128 citations

On the role of the H-2 histocompatibility complex in determining the specificity of cytotoxic effector cells sensitized against syngeneic trinitrophenyl-modified targets.

1975 • 127 citations

New genetic model for allelism at histocompatibility and other complex loci: polymorphism for control of gene expression.

1973 • 126 citations

The Role of the Histocompatibility-2-Linked Ss-Slp Region in the Control of Mouse Complement

1973 • 124 citations

Purification and structural analysis of the fourth component of human complement

1977 • 123 citations

Induction of cytotoxic T lymphocytes against I-region-coded determinants: in vitro evidence for a third histocompatibility locus in the mouse.

1975 • 121 citations

Association of a beta2-microglobulin-like subunit with H-2 and TL alloantigens on murine thymocytes.

1975 • 120 citations

Immunochemical characterization of murine H-2 controlled Ss (serum substance) protein through identification of its human homologue as the fourth component of complement.

1975 • 120 citations

Cell-free synthesis of the fourth component of guinea pig complement (C4): identification of a precursor of serum C4 (pro-C4).

1977 • 119 citations

T Lymphocyte-Enriched Murine Peritoneal Exudate Cells

1976 • 114 citations

Synthesis of 2 -microglobulin by stimulated lymphocytes.

1972 • 111 citations

Structural similarities between a product of the T/t-locus isolated from sperm and teratoma cells, and H-2 antigens isolated from splenocytes.

1975 • 110 citations

Primitive Teratocarcinoma Cells Express a Differentiation Antigen Specified by a Gene at the T-Locus in the Mouse

1974 • 110 citations

H-2 Histocompatibility alloantigens. Biochemical properties of the molecules solubilized by NP-40 detergent

1973 • 105 citations

Identification of Ss protein as murine C4

1975 • 102 citations

Nature of the antigenic complex recognized by T lymphocytes. I. Analysis with an in vitro primary response to soluble protein antigens.

1976 • 101 citations

Evolutionary relationship between immunoglobulins and transplantation antigens.

1975 • 97 citations

Synthesis of β2-Microglobulin by Stimulated Lymphocytes

1972 • 89 citations

Independent populations of primed F1 guinea pig T lymphocytes respond to antigen-pulsed parental peritoneal exudate cells.

1977 • 89 citations

Ir‐LDHB: Map position and functional analysis

1973 • 89 citations

H–2 linked Ss protein is C4 component of complement

1975 • 86 citations

Inhibition of Immune Responses in Vitro by Specific Antiserums to Ia Antigens

1975 • 85 citations

Thymus leukaemia antigen contains β2-microglobulin

1975 • 84 citations

Antigenic Properties of Experimental Leukemias. II. Immunological Studies <italic>In Vivo</italic> With C57BL/6 Radiation-Induced Leukemias<xref ref-type="fn" rid="FN2">2</xref>

1963 • 80 citations

An analysis of an antigenic system in the mouse (theH-2 system)

1955 • 77 citations

Immunologic properties of mouse thymus cells: Membrane antigen patterns

1973 • 76 citations

ANTIGENIC MODULATION IN VITRO

1974 • 75 citations

Structure and evolution of transplantation antigens: partial amino-acid sequences of H-2K and H-2D alloantigens.

1976 • 75 citations

Abnormalities Associated with a Chromosome Region in the Mouse

1964 • 75 citations

The Role of Products of the Histocompatibility Gene Complex in Immune Responses

1976 • 74 citations

Beta 2-microglobulin is selectively associated with H-2 and TL alloantigens on murine lymphoid cells.

1976 • 72 citations

The allogeneic bisection of carrier-specific enhancement of monoclonal B-cell responses.

1975 • 72 citations

Dog Homologue of Human β 2 -Microglobulin

1972 • 72 citations

Localization of the papain cleavage site of H-2 glycoproteins.

1976 • 70 citations

Leukocyte Membrane Determinants Regulating Immune Reactivity

1976 • 68 citations

Association of H-2 Types with Genetic Control of Immune Responsiveness to IgA Allotypes in the Mouse

1971 • 67 citations

Relationships between private and public H-2 specificities on the cell surface

1975 • 66 citations

The partial amino-acid sequence of an H-2K molecule.

1976 • 66 citations

IMMUNOLOGIC PROPERTIES OF MOUSE THYMUS CELLS

1972 • 66 citations

THE RELATIONSHIP BETWEEN ß2-MICROGLOBULIN AND IMMUNOGLOBULIN IN CULTURED HUMAN LYMPHOID CELL LINES

1973 • 64 citations

Human Ia Antigens -- Purification and Molecular Structure

1977 • 64 citations

Structure of murine Ia antigens: partial NH2-terminal amino acid sequences of products of the I-E or I-C subregion.

1977 • 63 citations

BIOCHEMICAL PROPERTIES OF HISTOCOMPATIBILITY ANTIGENS

1970 • 63 citations

B-Cell Alloantigens Determined by the H-2 Linked Ir Region Are Associated with Mixed Lymphocyte Culture Stimulation

1974 • 60 citations

Isolation and characterization of H-2 and TL alloantigens from the surface of mouse lymphocytes

1972 • 60 citations

Physical-chemical properties of β2-microglobulin

1974 • 60 citations

Leucocyte Membrane Determinants Regulating Immune Reactivity

1978 • 58 citations

Partial characterization of Ia antigens from murine lymphoid cells

1974 • 57 citations

Effects of anti-Ia sera on mitogenic responses. III. Mapping the genes controlling the expression of Ia determinants on concanavalin A-reactive cells to the I-J subregion of the H-2 gene complex.

1976 • 56 citations

Immunochemical evidence for an additional H-2 region closely linked to H-2D.

1977 • 56 citations

Isolation and characterization of murine Ia antigens

1975 • 55 citations

Chemical Characterization of Products of the H-2 Complex

1977 • 53 citations

Characterization of a Constitutive Variant of the Murine Serum Protein Allotype, Slp

1976 • 53 citations

Fine structural study of cell migration in the early mesoderm of normal and mutant mouse embryos (T-locus: t9/t9)

1974 • 53 citations

Modulation of TL (thymus-leukemia) antigens by Fab-fragments of TL antibody.

1968 • 52 citations

Expression of Ia antigens on hapten-specific B cells. I. Delineation of B-cell subpopulations.

1976 • 49 citations

ABNORMALITIES ASSOCIATED WITH A CHROMOSOME REGION IN THE MOUSE. II. EMBRYOLOGICAL EFFECTS OF LETHAL ALLELES IN THE T-REGION.

1964 • 47 citations

A neuroendocrine feedback mechanism in the insect moulting cycle

1975 • 45 citations

THE 11,000-DALTON COMPONENT OF MOUSE II-2 ISOLATION AND IDENTIFCATION

1974 • 45 citations

Structural studies on induced antibodies with defined idiotypic specificities. II. The light chains of anti-p-azophenylarsonate antibodies from A/J mice bearing a cross-reactive idiotype.

1975 • 44 citations

Presence of a Mouse Embryonic Antigen on Human Spermatozoa

1974 • 44 citations

Structural studies on protein products of murine chromosome 17: partial amino acid sequence of an H-2Kb molecule.

1976 • 43 citations

SOME BIOCHEMICAL PROPERTIES OF THYMUS LEUKEMIA ANTIGENS SOLUBILIZED FROM CELL MEMBRANES BY PAPAIN DIGESTION

1973 • 43 citations

Low-molecular-weight Ia antigens in normal mouse serum

1976 • 42 citations

Isolation and characteristics of a rabbit β2-microglobulin: Comparison with human β2-microglobulin

1974 • 41 citations

ASSOCIATION OF H-2 TYPES WITH GENETIC CONTROL OF IMMUNE RESPONSIVENESS TO I<scp>G</scp>G (γ2a) ALLOTYPES IN THE MOUSE

1972 • 40 citations

Chemical and Immunological Characterization of HL-A-linked B-lymphocyte Alloantigens

1977 • 40 citations

Homology of (murine) H–2 and (human) HLA with a chicken histocompatibility antigen

1977 • 39 citations

Molecular relationship between private and public H-2 antigens as determined by antigen redistribution method.

1975 • 37 citations

ABSENCE OF A SEROLOGICALLY DETECTABLE ASSOCIATION OF MURINE β2-MICROGLOBULIN WITH THE EMBRYONIC F9 ANTIGEN

1976 • 37 citations

Amino acid composition and physicochemical properties of mouse β2-microglobulin

1975 • 37 citations

Partial amino acid sequence of mouse β2-microglobulin

1976 • 37 citations

Subunit structure of thymus leukemia antigens

1975 • 36 citations

Observations on a set of radiation-induced dominantT-like mutations in the mouse

1975 • 35 citations

HLA membrane antigens: sequencing by intrinsic radioactivity.

1976 • 35 citations

Sites of Localization and Synthesis of Ss Protein in Mice

1974 • 31 citations

Genetic control of haemolytic complement in mice: association with H-2.

1972 • 31 citations

Studies on the effect of specific antisera on the metabolism of cellular antigens. II. The synthesis and degradation of TL antigens of mouse cells in the presence of TL antiserum.

1974 • 30 citations

Characterization of a newIr-GLT gene and its location in theI-region of theH-2 complex

1974 • 29 citations

Low molecular weight Ia antigens in normal mouse serum

1976 • 29 citations

Modulation of TL (Thymus-Leukemia) Antigens by Fab-Fracments of TL Antibody

1968 • 29 citations

THE TIME OF APPEARANCE OF Ia ANTIGENS DURING SPERMATOGENESIS IN THE MOUSE

1976 • 28 citations

Chemical and immunologic characterization of a β2-microglobulin-like protein isolated from chicken sera

1977 • 27 citations

An approach to amino acid sequence analysis of transplantation antigens

1975 • 26 citations

Labeling Characteristics and Separation of Ia Antigen Subunits

1978 • 26 citations

Partial Amino Acid Sequence of Rabbit β 2 -Microglobulin

1975 • 26 citations

The Biological Effects of Polynucleotides

1972 • 26 citations

The expression of human beta2 microglobulin on human spermatozoa

1976 • 25 citations

Structure of Murine Histocompatibility Antigens

1977 • 25 citations

Structural Studies on Induced Antibodies with Defined Idiotypic Specificities

1975 • 24 citations

Studies on the Effect of Specific Antisera on the Metabolism of Cellular Antigens

1974 • 24 citations

The partial amino acid sequence of a murine Ia molecule

1977 • 23 citations

Different Mechanisms for the Modulation of TL Antigens on Murine Lymphoid Cells

1976 • 22 citations

Relationship of Functional Levels of Early Components of Complement to the H-2 Complex of Mice

1976 • 22 citations

A comment on the genetic data relating to expression of TL antigens.

1971 • 22 citations

Human Cell Membrane Components Bound to β2-Microglobulin in T Cell-Type Cell Lines

1978 • 22 citations

Studies on the murine Ss protein. I. Purification, molecular weight, and subunit structure.

1975 • 21 citations

PRODUCTION OF TL ANTIBODY BY MICE IMMUNIZED WITH TL- CELL POPULATIONS

1973 • 19 citations

Detection of β2‐Microglobulin in Sera from Diverse Vertebrate Species by the Use of a Heterologous Radioimmunoassay

1976 • 17 citations

The Guinea Pig MHC: Functional Significance and Structural Characterization

1977 • 17 citations

A COMMENT ON THE GENETIC DATA RELATING TO EXPRESSION OF TL ANTIGENS

1971 • 16 citations

Distribution and mobility of beta 2-microglobulin on the human lymphocyte membrane: immunofluorescence and immunoferritin studies.

1974 • 15 citations

The Immune Response to Staphylococcal Nuclease: A Probe of Cellular and Humoral Antigen-specific Receptors

1977 • 15 citations

Distribution and Mobility of β2-Microglobulin on the Human Lymphocyte Membrane: Immunofluorescence and Immunoferritin Studies

1974 • 15 citations

Relationship between beta2-microglobulin and cell-surface alloantigens of the mouse.

1976 • 15 citations

Enzymatic removal of H‐2 alloantigens from the surface of P815‐(X2) mouse tumor cells

1976 • 13 citations

Relationship between β2-Microglobulin and Cell-Surface Alloantigens of the Mouse

1976 • 13 citations

Detection and isolation of an Ia glycoprotein antigen from mouse serum

1977 • 11 citations

Subfragments of Papain Solubilized TL Antigen

1975 • 11 citations

Peptide comparison of two histocompatibility-2 (H-2b and H-2d) alloantigens

1972 • 10 citations

Further structural studies on the F9 (T/t) antigen(s)

1977 • 8 citations

CHROMOSOMAL ASSIGNMENT OF THE HL‐A COMMON ANTIGENIC DETERMINANTS IN MAN‐MOUSE SOMATIC CELL HYBRIDS*

1976 • 4 citations

Purification of murine thymus leukemia antigen (TL). Quantitative assessment of limited proteolysis

1975 • 3 citations

Cited By (0)

Loading...
The Protein Products of the Murine 17th Chromosome: Genetics and Structure (1978) – Advances in immunology | Metascience Observatory Explorer