The Protein Products of the Murine 17th Chromosome: Genetics and Structure
Data up to Jan 2025
Total Citations Per Year
Abstract
References (157)
Rapid Isolation of Antigens from Cells with A Staphylococcal Protein A-Antibody Adsorbent: Parameters of the Interaction of Antibody-Antigen Complexes with Protein A
1975 • 3,054 citations
Progress in Clinical and Biological Research
1979 • 1,317 citations
Biology of the Mouse Histocompatibility-2 Complex
1975 • 1,145 citations
The H-2 Major Histocompatibility Complex and the/Immune Response Region: Genetic Variation, Function, and Organization
1975 • 774 citations
Isolation and Properties of a Low Molecular Weight β2-Globulin Occurring in Human Biological Fluids
1968 • 733 citations
Progress in Clinical and Biological Research
1984 • 554 citations
Cell-mediated lympholysis of trinitrophenyl-modified autologous lymphocytes. Effector cell specificity to modified cell surface components controlled by H-2K and H-2D serological regions of the murine major histocompatibility complex.
1975 • 381 citations
The role of macrophages in the generation of T-helper cells. II. The genetic control of the macrophage-T-cell interaction for helper cell induction with soluble antigens.
1975 • 364 citations
A new I subregion (I-J) marked by a locus (Ia-4) controlling surface determinants on suppressor T lymphocytes.
1976 • 353 citations
Surface Antigens Common to Mouse Cleavage Embryos and Primitive Teratocarcinoma Cells in Culture
1973 • 330 citations
ANTIGENIC MODULATION
1968 • 322 citations
The genetic and antigenic basis of tumour transplantation
1937 • 313 citations
Development of the short‐tailed mutant in the house mouse
1935 • 305 citations
New Lymphocyte Antigen System ( Lna ) Controlled by the Ir Region of the Mouse H-2 Complex
1973 • 282 citations
A MOUSE B-CELL ALLOANTIGEN DETERMINED BY GENE(S) LINKED TO THE MAJOR HISTOCOMPATIBILITY COMPLEX
1973 • 274 citations
The β2-microglobulin gene is on chromosome 15 and not in the HL-A region
1975 • 274 citations
Mouse Teratocarcinoma and Embryonic Antigens
1977 • 270 citations
The H-2 locus of the mouse: observations and speculations concerning its comparative genetics and its polymorphism.
1968 • 238 citations
EVIDENCE FOR THE EXPRESSION OF Ia (H-2-ASSOCIATED) ANTIGENS ON THYMUS-DERIVED LYMPHOCYTES
1974 • 233 citations
ACTIVATION OF T AND B LYMPHOCYTES IN VITRO
1974 • 231 citations
Antigenic Properties of Experimental Leukemias. I. Serological Studies <italic>In Vitro</italic> With Spontaneous and Radiation-Induced Leuke-mias<xref ref-type="fn" rid="FN2">2</xref>
1963 • 225 citations
THE ROLE OF PRODUCTS OF THE HISTOCOMPATIBILITY GENE COMPLEX IN IMMUNE RESPONSES
1975 • 223 citations
Production of Large Amounts of Antibodies in Individual Mice
1976 • 212 citations
Tissue distribution of ia antigens: Ia on spermatozoa, macrophages, and epidermal cells
1974 • 210 citations
Hypervariable Regions, Idiotypy, and the Antibody-Combining Site
1975 • 201 citations
The Histocompatibility-Linked Immune Response Genes
1975 • 186 citations
HISTOCOMPATIBILITY-LINKED IMMUNE RESPONSE GENE FUNCTION IN GUINEA PIGS
1972 • 186 citations
Serological Identification of an Ir-Region Product
1973 • 182 citations
GENETIC CONTROL OF THE ANTIBODY RESPONSE
1967 • 178 citations
EVIDENCE FOR IDENTITY OR CLOSE ASSOCIATION OF THE Fc RECEPTOR OF B LYMPHOCYTES AND ALLOANTIGENS DETERMINED BY THE Ir REGION OF THE H-2 COMPLEX
1974 • 173 citations
Antigen-specific T-cell factor in cell cooperation. Mapping within the I region of the H-2 complex and ability to cooperate across allogeneic barriers.
1975 • 172 citations
Structure of HLA antigens: amino-acid and carbohydrate compositions and NH2-terminal sequences of four antigen preparations.
1976 • 168 citations
TheTla region of the mouse: Identification of a new serologically defined locus,Qa-2
1976 • 168 citations
Modification of the antigenic structure of the cell membrane by thymus-leukemia (TL) antibody.
1967 • 160 citations
T lymphocyte-enriched murine peritoneal exudate cells. III. Inhibition of antigen-induced T lymphocyte Proliferation with anti-Ia antisera.
1976 • 158 citations
A new serologically defined locus,Qa-1, in theTla-region of the mouse
1976 • 156 citations
Molecular similarities between the Qa-2 alloantigen and other gene products of the 17th chromosome of the mouse.
1977 • 146 citations
Isolation of H-2 Alloantigens Solubilized by the Detergent NP-40
1971 • 146 citations
Biochemical properties and immunochemical-genetic relationships of mouse H-2 alloantigens
1974 • 143 citations
ACTIVATION OF T AND B LYMPHOCYTES IN VITRO
1974 • 142 citations
Membrane Molecules Determined by the H-2 Associated Immune Response Region: Isolation and Some Properties
1974 • 134 citations
Selective expression of H-2 (i-region) loci controlling determinants on helper and suppressor T lymphocytes.
1976 • 131 citations
Notable diversity in peptide composition of murine H-2K and H-2D alloantigens
1974 • 129 citations
Detergent-solubilised H-2 alloantigen is associated with a small molecular weight polypeptide
1974 • 129 citations
Subunit structure, cell surface orientation, and partial amino-acid sequences of murine histocompatibility antigens.
1976 • 128 citations
On the role of the H-2 histocompatibility complex in determining the specificity of cytotoxic effector cells sensitized against syngeneic trinitrophenyl-modified targets.
1975 • 127 citations
New genetic model for allelism at histocompatibility and other complex loci: polymorphism for control of gene expression.
1973 • 126 citations
The Role of the Histocompatibility-2-Linked Ss-Slp Region in the Control of Mouse Complement
1973 • 124 citations
Purification and structural analysis of the fourth component of human complement
1977 • 123 citations
Induction of cytotoxic T lymphocytes against I-region-coded determinants: in vitro evidence for a third histocompatibility locus in the mouse.
1975 • 121 citations
Association of a beta2-microglobulin-like subunit with H-2 and TL alloantigens on murine thymocytes.
1975 • 120 citations
Immunochemical characterization of murine H-2 controlled Ss (serum substance) protein through identification of its human homologue as the fourth component of complement.
1975 • 120 citations
Cell-free synthesis of the fourth component of guinea pig complement (C4): identification of a precursor of serum C4 (pro-C4).
1977 • 119 citations
T Lymphocyte-Enriched Murine Peritoneal Exudate Cells
1976 • 114 citations
Synthesis of 2 -microglobulin by stimulated lymphocytes.
1972 • 111 citations
Structural similarities between a product of the T/t-locus isolated from sperm and teratoma cells, and H-2 antigens isolated from splenocytes.
1975 • 110 citations
Primitive Teratocarcinoma Cells Express a Differentiation Antigen Specified by a Gene at the T-Locus in the Mouse
1974 • 110 citations
H-2 Histocompatibility alloantigens. Biochemical properties of the molecules solubilized by NP-40 detergent
1973 • 105 citations
Identification of Ss protein as murine C4
1975 • 102 citations
Nature of the antigenic complex recognized by T lymphocytes. I. Analysis with an in vitro primary response to soluble protein antigens.
1976 • 101 citations
Evolutionary relationship between immunoglobulins and transplantation antigens.
1975 • 97 citations
Synthesis of β2-Microglobulin by Stimulated Lymphocytes
1972 • 89 citations
Independent populations of primed F1 guinea pig T lymphocytes respond to antigen-pulsed parental peritoneal exudate cells.
1977 • 89 citations
Ir‐LDHB: Map position and functional analysis
1973 • 89 citations
H–2 linked Ss protein is C4 component of complement
1975 • 86 citations
Inhibition of Immune Responses in Vitro by Specific Antiserums to Ia Antigens
1975 • 85 citations
Thymus leukaemia antigen contains β2-microglobulin
1975 • 84 citations
Antigenic Properties of Experimental Leukemias. II. Immunological Studies <italic>In Vivo</italic> With C57BL/6 Radiation-Induced Leukemias<xref ref-type="fn" rid="FN2">2</xref>
1963 • 80 citations
An analysis of an antigenic system in the mouse (theH-2 system)
1955 • 77 citations
Immunologic properties of mouse thymus cells: Membrane antigen patterns
1973 • 76 citations
ANTIGENIC MODULATION IN VITRO
1974 • 75 citations
Structure and evolution of transplantation antigens: partial amino-acid sequences of H-2K and H-2D alloantigens.
1976 • 75 citations
Abnormalities Associated with a Chromosome Region in the Mouse
1964 • 75 citations
The Role of Products of the Histocompatibility Gene Complex in Immune Responses
1976 • 74 citations
Beta 2-microglobulin is selectively associated with H-2 and TL alloantigens on murine lymphoid cells.
1976 • 72 citations
The allogeneic bisection of carrier-specific enhancement of monoclonal B-cell responses.
1975 • 72 citations
Dog Homologue of Human β 2 -Microglobulin
1972 • 72 citations
Localization of the papain cleavage site of H-2 glycoproteins.
1976 • 70 citations
Leukocyte Membrane Determinants Regulating Immune Reactivity
1976 • 68 citations
Association of H-2 Types with Genetic Control of Immune Responsiveness to IgA Allotypes in the Mouse
1971 • 67 citations
Relationships between private and public H-2 specificities on the cell surface
1975 • 66 citations
The partial amino-acid sequence of an H-2K molecule.
1976 • 66 citations
IMMUNOLOGIC PROPERTIES OF MOUSE THYMUS CELLS
1972 • 66 citations
THE RELATIONSHIP BETWEEN ß2-MICROGLOBULIN AND IMMUNOGLOBULIN IN CULTURED HUMAN LYMPHOID CELL LINES
1973 • 64 citations
Human Ia Antigens -- Purification and Molecular Structure
1977 • 64 citations
Structure of murine Ia antigens: partial NH2-terminal amino acid sequences of products of the I-E or I-C subregion.
1977 • 63 citations
BIOCHEMICAL PROPERTIES OF HISTOCOMPATIBILITY ANTIGENS
1970 • 63 citations
B-Cell Alloantigens Determined by the H-2 Linked Ir Region Are Associated with Mixed Lymphocyte Culture Stimulation
1974 • 60 citations
Isolation and characterization of H-2 and TL alloantigens from the surface of mouse lymphocytes
1972 • 60 citations
Physical-chemical properties of β2-microglobulin
1974 • 60 citations
Leucocyte Membrane Determinants Regulating Immune Reactivity
1978 • 58 citations
Partial characterization of Ia antigens from murine lymphoid cells
1974 • 57 citations
Effects of anti-Ia sera on mitogenic responses. III. Mapping the genes controlling the expression of Ia determinants on concanavalin A-reactive cells to the I-J subregion of the H-2 gene complex.
1976 • 56 citations
Immunochemical evidence for an additional H-2 region closely linked to H-2D.
1977 • 56 citations
Isolation and characterization of murine Ia antigens
1975 • 55 citations
Chemical Characterization of Products of the H-2 Complex
1977 • 53 citations
Characterization of a Constitutive Variant of the Murine Serum Protein Allotype, Slp
1976 • 53 citations
Fine structural study of cell migration in the early mesoderm of normal and mutant mouse embryos (T-locus: t9/t9)
1974 • 53 citations
Modulation of TL (thymus-leukemia) antigens by Fab-fragments of TL antibody.
1968 • 52 citations
Expression of Ia antigens on hapten-specific B cells. I. Delineation of B-cell subpopulations.
1976 • 49 citations
ABNORMALITIES ASSOCIATED WITH A CHROMOSOME REGION IN THE MOUSE. II. EMBRYOLOGICAL EFFECTS OF LETHAL ALLELES IN THE T-REGION.
1964 • 47 citations
A neuroendocrine feedback mechanism in the insect moulting cycle
1975 • 45 citations
THE 11,000-DALTON COMPONENT OF MOUSE II-2 ISOLATION AND IDENTIFCATION
1974 • 45 citations
Structural studies on induced antibodies with defined idiotypic specificities. II. The light chains of anti-p-azophenylarsonate antibodies from A/J mice bearing a cross-reactive idiotype.
1975 • 44 citations
Presence of a Mouse Embryonic Antigen on Human Spermatozoa
1974 • 44 citations
Structural studies on protein products of murine chromosome 17: partial amino acid sequence of an H-2Kb molecule.
1976 • 43 citations
SOME BIOCHEMICAL PROPERTIES OF THYMUS LEUKEMIA ANTIGENS SOLUBILIZED FROM CELL MEMBRANES BY PAPAIN DIGESTION
1973 • 43 citations
Low-molecular-weight Ia antigens in normal mouse serum
1976 • 42 citations
Isolation and characteristics of a rabbit β2-microglobulin: Comparison with human β2-microglobulin
1974 • 41 citations
ASSOCIATION OF H-2 TYPES WITH GENETIC CONTROL OF IMMUNE RESPONSIVENESS TO I<scp>G</scp>G (γ2a) ALLOTYPES IN THE MOUSE
1972 • 40 citations
Chemical and Immunological Characterization of HL-A-linked B-lymphocyte Alloantigens
1977 • 40 citations
Homology of (murine) H–2 and (human) HLA with a chicken histocompatibility antigen
1977 • 39 citations
Molecular relationship between private and public H-2 antigens as determined by antigen redistribution method.
1975 • 37 citations
ABSENCE OF A SEROLOGICALLY DETECTABLE ASSOCIATION OF MURINE β2-MICROGLOBULIN WITH THE EMBRYONIC F9 ANTIGEN
1976 • 37 citations
Amino acid composition and physicochemical properties of mouse β2-microglobulin
1975 • 37 citations
Partial amino acid sequence of mouse β2-microglobulin
1976 • 37 citations
Subunit structure of thymus leukemia antigens
1975 • 36 citations
Observations on a set of radiation-induced dominantT-like mutations in the mouse
1975 • 35 citations
HLA membrane antigens: sequencing by intrinsic radioactivity.
1976 • 35 citations
Sites of Localization and Synthesis of Ss Protein in Mice
1974 • 31 citations
Genetic control of haemolytic complement in mice: association with H-2.
1972 • 31 citations
Studies on the effect of specific antisera on the metabolism of cellular antigens. II. The synthesis and degradation of TL antigens of mouse cells in the presence of TL antiserum.
1974 • 30 citations
Characterization of a newIr-GLT gene and its location in theI-region of theH-2 complex
1974 • 29 citations
Low molecular weight Ia antigens in normal mouse serum
1976 • 29 citations
Modulation of TL (Thymus-Leukemia) Antigens by Fab-Fracments of TL Antibody
1968 • 29 citations
THE TIME OF APPEARANCE OF Ia ANTIGENS DURING SPERMATOGENESIS IN THE MOUSE
1976 • 28 citations
Chemical and immunologic characterization of a β2-microglobulin-like protein isolated from chicken sera
1977 • 27 citations
An approach to amino acid sequence analysis of transplantation antigens
1975 • 26 citations
Labeling Characteristics and Separation of Ia Antigen Subunits
1978 • 26 citations
Partial Amino Acid Sequence of Rabbit β 2 -Microglobulin
1975 • 26 citations
The Biological Effects of Polynucleotides
1972 • 26 citations
The expression of human beta2 microglobulin on human spermatozoa
1976 • 25 citations
Structure of Murine Histocompatibility Antigens
1977 • 25 citations
Structural Studies on Induced Antibodies with Defined Idiotypic Specificities
1975 • 24 citations
Studies on the Effect of Specific Antisera on the Metabolism of Cellular Antigens
1974 • 24 citations
The partial amino acid sequence of a murine Ia molecule
1977 • 23 citations
Different Mechanisms for the Modulation of TL Antigens on Murine Lymphoid Cells
1976 • 22 citations
Relationship of Functional Levels of Early Components of Complement to the H-2 Complex of Mice
1976 • 22 citations
A comment on the genetic data relating to expression of TL antigens.
1971 • 22 citations
Human Cell Membrane Components Bound to β2-Microglobulin in T Cell-Type Cell Lines
1978 • 22 citations
Studies on the murine Ss protein. I. Purification, molecular weight, and subunit structure.
1975 • 21 citations
PRODUCTION OF TL ANTIBODY BY MICE IMMUNIZED WITH TL- CELL POPULATIONS
1973 • 19 citations
Detection of β2‐Microglobulin in Sera from Diverse Vertebrate Species by the Use of a Heterologous Radioimmunoassay
1976 • 17 citations
The Guinea Pig MHC: Functional Significance and Structural Characterization
1977 • 17 citations
A COMMENT ON THE GENETIC DATA RELATING TO EXPRESSION OF TL ANTIGENS
1971 • 16 citations
Distribution and mobility of beta 2-microglobulin on the human lymphocyte membrane: immunofluorescence and immunoferritin studies.
1974 • 15 citations
The Immune Response to Staphylococcal Nuclease: A Probe of Cellular and Humoral Antigen-specific Receptors
1977 • 15 citations
Distribution and Mobility of β2-Microglobulin on the Human Lymphocyte Membrane: Immunofluorescence and Immunoferritin Studies
1974 • 15 citations
Relationship between beta2-microglobulin and cell-surface alloantigens of the mouse.
1976 • 15 citations
Enzymatic removal of H‐2 alloantigens from the surface of P815‐(X2) mouse tumor cells
1976 • 13 citations
Relationship between β2-Microglobulin and Cell-Surface Alloantigens of the Mouse
1976 • 13 citations
Detection and isolation of an Ia glycoprotein antigen from mouse serum
1977 • 11 citations
Subfragments of Papain Solubilized TL Antigen
1975 • 11 citations
Peptide comparison of two histocompatibility-2 (H-2b and H-2d) alloantigens
1972 • 10 citations
Further structural studies on the F9 (T/t) antigen(s)
1977 • 8 citations
CHROMOSOMAL ASSIGNMENT OF THE HL‐A COMMON ANTIGENIC DETERMINANTS IN MAN‐MOUSE SOMATIC CELL HYBRIDS*
1976 • 4 citations
Purification of murine thymus leukemia antigen (TL). Quantitative assessment of limited proteolysis
1975 • 3 citations