Rat liver peroxisomes catalyze the initial step in cholesterol synthesis. The condensation of acetyl-CoA units into acetoacetyl-CoA.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A fatty acyl-CoA oxidizing system in rat liver peroxisomes; enhancement by clofibrate, a hypolipidemic drug.

1976 • 1,136 citations

THE LARGE-SCALE SEPARATION OF PEROXISOMES, MITOCHONDRIA, AND LYSOSOMES FROM THE LIVERS OF RATS INJECTED WITH TRITON WR-1339

1968 • 1,112 citations

Carcinogenesis by Hepatic Peroxisome Proliferators: Evaluation of the Risk of Hypolipidemic Drugs and Industrial Plasticizers to Humans

1983 • 890 citations

ANALYTICAL STUDY OF MICROSOMES AND ISOLATED SUBCELLULAR MEMBRANES FROM RAT LIVER

1974 • 840 citations

Rat liver peroxisomes catalyze the beta oxidation of fatty acids.

1978 • 608 citations

Hepatic Peroxisome Proliferation: Induction by Two Novel Compounds Structurally Unrelated to Clofibrate

1975 • 349 citations

Intracellular localization of the 3-hydroxy-3-methylglutaryl coenzme A cycle enzymes in liver. Separate cytoplasmic and mitochondrial 3-hydroxy-3-methylglutaryl coenzyme A generating systems for cholesterogenesis and ketogenesis.

1975 • 258 citations

The oxoacyl-coenzyme A thiolases of animal tissues

1973 • 198 citations

The Presence of a New 3‐Oxoacyl‐CoA Thiolase in Rat Liver Peroxisomes

1980 • 196 citations

Subcellular localization of sterol carrier protein-2 in rat hepatocytes: its primary localization to peroxisomes.

1989 • 191 citations

Structural analysis of cDNA for rat peroxisomal 3-ketoacyl-CoA thiolase.

1987 • 159 citations

3-Hydroxy-3-methylglutaryl-coenzyme A reductase is present in peroxisomes in normal rat liver cells.

1985 • 158 citations

3-Hydroxy-3-methylglutaryl coenzyme A reductase localization in rat liver peroxisomes and microsomes of control and cholestyramine-treated animals: quantitative biochemical and immunoelectron microscopical analyses.

1986 • 147 citations

On the mechanism of malonyl-CoA-independent fatty acid synthesis

1968 • 138 citations

Partial disassembly of peroxisomes.

1985 • 130 citations

Molecular and Catalytic Properties of Cytosolic Acetoacetyl Coenzyme A Thiolase from Avian Liver

1973 • 128 citations

Cholesterol synthesis in rat liver peroxisomes. Conversion of mevalonic acid to cholesterol.

1987 • 117 citations

Purification and properties of a pig heart thiolase with broad chain length specificity and comparison of thiolases from pig heart and Escherichia coli.

1978 • 115 citations

Properties of Peroxisomal 3-Ketoacyl-CoA Thiolase from Rat Liver1

1981 • 98 citations

Quantitative Microscopy Comparison of Peroxisome Proliferation by the Lipid-Regulating Agent Gemfibrozil in Several Species

1984 • 96 citations

[98a] Phosphoglucose isomerase

1966 • 92 citations

Nonspecific Lipid Transfer Protein (Sterol Carrier Protein-2) Is Located in Rat Liver Peroxisomes1

1988 • 85 citations

The acetoacetyl-coenzyme A thiolases of rat brain and their relative activities during postnatal development

1973 • 77 citations

Synthesis of 3-ketoacyl-CoA thiolase of rat liver peroxisomes on free polyribosomes as a larger precursor. Induction of thiolase mRNA activity by clofibrate

1985 • 73 citations

LOCALIZATION OF THE ENZYMES OF KETOGENESIS IN RAT LIVER MITOCHONDRIA

1973 • 47 citations

Some comparative effects of gemfibrozil, clofibrate, bezafibrate, cholestyramine and compactin on sterol metabolism in rats

1983 • 33 citations

Zonal heterogeneity of peroxisome proliferation and morphology in rat liver after gemfibrozil treatment.

1989 • 30 citations

A survey of enzymes which generate or use acetoacetyl thioesters in rat liver.

1983 • 28 citations

Intraparticulate Localization of Some Peroxisomal Enzymes Related to Fatty Acid β‐Oxidation

1981 • 24 citations

Existence of acetyl-CoA-dependent chain elongation system in hepatic peroxisomes of rat: Effects of clofibrate and di-(2-ethylhexyl)phthalate on the activity

1989 • 24 citations

Occurrence and possible roles of acetoacetyl‐CoA thiolase and 3‐ketoacyl‐CoA thiolase in peroxisomes of an n‐alkane‐grown yeast, Candida tropicalis

1988 • 23 citations

Drugs affecting lipid metabolism

1980 • 18 citations

FINE STRUCTURAL CHANGES IN THE HEPATIC MICROBODIES OF RATS TREATED WITH HYPOLIPIDEMIC AGENTS, GEMFIBROZIL AND CLOFIBRATE

1978 • 13 citations

Effects of starvation and development on mitochondrial acetoacetyl-coenzyme A thiolase of rat liver

1977 • 9 citations