Naturally processed class II epitope from the tumor antigen MUC1 primes human CD4+ T cells.
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Abstract
References (9)
Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size
1992 • 763 citations
Peptides Presented to the Immune System by the Murine Class II Major Histocompatibility Complex Molecule I-A d
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Specific, major histocompatibility complex-unrestricted recognition of tumor-associated mucins by human cytotoxic T cells.
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Cytotoxic T-lymphocytes derived from patients with breast adenocarcinoma recognize an epitope present on the protein core of a mucin molecule preferentially expressed by malignant cells.
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Humoral immunity against a tandem repeat epitope of human mucin MUC-1 in sera from breast, pancreatic, and colon cancer patients.
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Induction of HLA-A2-restricted CTLs to the mucin 1 human breast cancer antigen.
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HLA-DR3 molecules can bind peptides carrying two alternative specific submotifs.
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Human Tumor Antigens Are Ready to Fly
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Motifs and supermotifs for MHC class II binding peptides.
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