Type III InsP3 receptor channel stays open in the presence of increased calcium

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

2012 • 8,865 citations

Bell-shaped calcium-response curves of lns(l,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum

1991 • 1,699 citations

Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides

1993 • 1,259 citations

Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400

1989 • 1,039 citations

Putative receptor for inositol 1,4,5-trisphosphate similar to ryanodine receptor

1989 • 531 citations

Local and global cytosolic Ca2+ oscillations in exocrine cells evoked by agonists and inositol trisphosphate

1993 • 488 citations

Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux

1995 • 484 citations

Spatial and temporal aspects of cellular calcium signaling

1996 • 480 citations

Type I, II, and III Inositol 1,4,5-Trisphosphate Receptors Are Unequally Susceptible to Down-regulation and Are Expressed in Markedly Different Proportions in Different Cell Types

1995 • 418 citations

Structure of a novel InsP3 receptor.

1991 • 383 citations

Cooking with Calcium: The Recipes for Composing Global Signals from Elementary Events

1997 • 367 citations

Subcellular distribution of Ca2+ release channels underlying Ca2+ waves and oscillations in exocrine pancreas

1993 • 357 citations

Sequence and functional characterization of a third inositol trisphosphate receptor subtype, IP3R-3, expressed in pancreatic islets, kidney, gastrointestinal tract, and other tissues

1993 • 313 citations

Isolated rat hepatocytes can signal to other hepatocytes and bile duct cells by release of nucleotides.

1996 • 225 citations

Inositol (1,4,5)-trisphosphate (InsP3)-gated Ca channels from cerebellum: conduction properties for divalent cations and regulation by intraluminal calcium.

1994 • 212 citations

Localization of the type 3 inositol 1,4,5-trisphosphate receptor in the Ca2+ wave trigger zone of pancreatic acinar cells.

1994 • 205 citations

Nuclear calcium signalling by individual cytoplasmic calcium puffs

1997 • 181 citations

Primary structure, ligand binding, and localization of the human type 3 inositol 1,4,5-trisphosphate receptor expressed in intestinal epithelium.

1994 • 173 citations

Identification and Functional Reconstitution of the Type 2 Inositol 1,4,5-Trisphosphate Receptor from Ventricular Cardiac Myocytes

1997 • 160 citations

Mechanism of Ca2+ wave propagation in pancreatic acinar cells.

1992 • 159 citations

Inositol 1,4,5-Trisphosphate (InsP3) and Calcium Interact to Increase the Dynamic Range of InsP3 Receptor-dependent Calcium Signaling

1997 • 151 citations

Ca2+ transients associated with openings of inositol trisphosphate‐gated channels in Xenopus oocytes.

1996 • 136 citations

Differential regulation of types-1 and -3 inositol trisphosphate receptors by cytosolic Ca2+

1997 • 97 citations

Evidence for two Ca2+-mobilizing purinoceptors on rat hepatocytes

1990 • 92 citations

Mechanisms for the coordination of intercellular calcium signaling in insulin secreting cells

1997 • 89 citations

Ca2+ differentially regulates the ligand-affinity states of type 1 and type 3 inositol 1,4,5-trisphosphate receptors

1997 • 88 citations

Actions of vasopressin and the Ca(2+)-ATPase inhibitor, thapsigargin, on Ca2+ signaling in hepatocytes.

1992 • 87 citations

Expression of inositol 1,4,5-trisphosphate receptors changes the Ca2+ signal of Xenopus oocytes

1996 • 68 citations

Identification of three isoforms of the InsP 3 receptor in human myometrial smooth muscle

1996 • 48 citations

Inositol triphosphate produces different patterns of cytoplasmic Ca²⁺ spiking depending on its concentration

1991 • 36 citations