[57] Bifunctional reagents

Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 Å Resolution

1965 • 1,623 citations

Habilitationsschrift

2009 • 1,338 citations

Direct Evidence for the Presence of Histidine in the Active Center of Chymotrypsin^*

1963 • 649 citations

Glutaraldehyde as a protein cross-linking reagent

1968 • 542 citations

Reaction of proteins with glutaraldehyde

1968 • 507 citations

A Partial Determination by X-ray Methods, and its Correlation with Chemical Data

1961 • 486 citations

The Reaction of Imidoesters with Proteins and Related Small Molecules

1962 • 306 citations

Interstrand cross-linking of DNA by difunctional alkylating agents

1967 • 278 citations

Affinity Labelling of Antibodies with Aryl Nitrene as Reactive Group

1969 • 226 citations

Affinity Labeling—a General Method for Labeling the Active Sites of Antibody and Enzyme Molecules^*

1962 • 217 citations

Effects of the Amidination Reaction on Antibody Activity and on the Physical Properties of Some Proteins^*

1963 • 181 citations

The Chemistry of Maleimide and Its Derivatives. II. Maleimide and N-Methylolmaleimide

1961 • 181 citations

Interaction of DNA with Bifunctional Aldehydes

1968 • 171 citations

Inactivation of bacteriophage T7 by mono- and difunctional sulphur mustards in relation to cross-linking and depurination of bacteriophage DNA

1969 • 166 citations

Notes- Aliphatic Nitriles from Alkyl Chlorides

1960 • 147 citations

Orthoesters and Related Compounds from Malono- and Succinonitriles

1949 • 136 citations

Cross-Linking of Bovine Pancreatic Ribonuclease A with Dimethyl Adipimidate^*

1967 • 129 citations

On the Formation of Covalent Linkages between Two Protein Molecules

1961 • 124 citations

Bifunctional imidoesters as cross-linking reagents

1966 • 92 citations

PREPARATION OF ANTIBODY-FERRITIN CONJUGATES FOR IMMUNO-ELECTRON MICROSCOPY

1963 • 87 citations

Erythrocyte Membrane: Chemical Modification

1965 • 77 citations

Crosslinking during the nitration of bovine insulin with tetranitromethane

1970 • 73 citations

Cross-linking of Bovine Plasma Albumin and Wool Keratin

1956 • 73 citations

POTENTIAL ANTICANCER AGENTS.¹ LXVI. NON-CLASSICAL ANTIMETABOLITES. III.² 4-(IODOACETAMIDO)-SALICYLIC ACID, AN EXO-ALKYLATING IRREVERSIBLE INHIBITOR OF GLUTAMIC DEHYDROGENASE

1961 • 72 citations

Probable protein crosslinking with tetranitromethane

1968 • 70 citations

A Mechanism of the Irreversible Inactivation of Bovine Pancreatic Ribonuclease by Diethylpyrocarbonate

1970 • 69 citations

Reaktionen von 1,5‐difluor‐2,4‐dinitrobenzol mit insulin 1. Mitt. Synthese von modellverbindungen

1958 • 63 citations

Cross-linking of Polymers with Dimaleimides¹

1959 • 60 citations

Cross-linking of Aminotyrosyl Residues in the Active Site of Staphylococcal Nuclease

1969 • 60 citations

Reaktionen von 1,5‐difluor‐2,4‐dinitrobenzol mit insulin 2. Mitt. Versuche mit insulin

1958 • 57 citations

Preparation and properties of crosslinked water-insoluble catalase

1970 • 55 citations

The reactivity of radiomimetic compounds. 1. Cross-linking of proteins

1952 • 55 citations

The Reaction of Bovine Serum Albumin with the Bifunctional Reagent p,p′-Difluoro-m,m′-dinitro-diphenylsulfone

1961 • 52 citations

Reaction of Bovine Pancreatic Ribonuclease A with 1,5-Difluoro-2,4-dinitrobenzene

1965 • 52 citations

Reversible Blocking of Protein Amino Groups by the Acetimidyl Group

1962 • 50 citations

Identification of Dinitrophenylamino-Acids

1950 • 50 citations

Reaction of Bovine Pancreatic Ribonuclease A with 1,5-Difluoro-2,4-dinitrobenzene

1965 • 49 citations

Cross-linking of erythrocyte membranes with dimethyl adipimidate

1970 • 48 citations

Über einige reaktionsfähige Fluor‐Verbindungen der aromatischen Reihe

1953 • 46 citations

The Mechanism of Action of Aldolases

1965 • 44 citations

Intermolecular Reaction during Photolysis of Diazoacetyl α-Chymotrypsin

1971 • 39 citations

Reaktion von p , p ′‐Difluor‐ m , m ′‐dinitro‐diphenylsulfon mit Seidenfibroin

1956 • 34 citations

Bridging Reagent for Protein

1967 • 32 citations

S-Carboxymethylcysteine from the Photolysis of Diazoacyl Trypsin and Chymotrypsin

1971 • 31 citations

Crosslinked synthetic polypeptides. I. Preparation and characterization of crosslinked poly Glu⁵¹‐Lys³³Tyr¹⁶ and of poly Glu⁵²Lys³³Tyr¹⁵ no. 3

1965 • 29 citations

Isoelectric point of a protein in the crosslinked crystalline state: β-Lactoglobulin

1968 • 29 citations

Bifunctional reagents and protein structure determination. The reaction of phenolic disulfonyl chlorides with lysozyme

1964 • 26 citations

Antigenic properties of proteins cross-linked by multidiazonium compounds

1969 • 25 citations

The reaction of 4,4′-difluoro-3,3′-dinitro-diphenyl sulfone with γ-globulin and horseradish peroxidase

1971 • 25 citations

Notiz über Nitrophenylester

1963 • 25 citations

Structural and Functional Roles of the Cysteine Residues in the α Subunit of the Escherichia coli Tryptophan Synthetase

1971 • 24 citations

Kollagenuntersuchungen

1960 • 23 citations

Introduction of sulfhydryl groups into macromolecules

1959 • 18 citations

Bridging Reagent for Protein

1967 • 18 citations

Some properties of cross-linked bovine serum albumin

1961 • 18 citations

Introduction of Covalent Cross-Linkages into Lysozyme by Reaction with α,α′-Dibromo-p-xylenesulfonic Acid

1964 • 15 citations

Physicochemical and immunochemical studies on the reaction of bovine serum albumin with p,p′-difluoro-m,m′-dinitrodiphenylsulfone

1963 • 13 citations

Bemerkungen zu der vernetzungsreaktion von kollagen mit p,p′‐difluor‐m,m′‐dinitro‐diphenyi‐sulfon

1958 • 12 citations

Untersuchungen an Kollagen

1960 • 10 citations

Chemical modification of ribonuclease a crystals I. Reaction with 1,5-difluoro-2,4-dinitrobenzene

1965 • 10 citations

Über die Spezifität bifunktioneller SH-Reagenzien und die Synthese eines definierten Dimeren des Rinderserumalbumins

1968 • 9 citations

Cross-linking in Collagen by Potassium Nitrosyldisulphonate

1968 • 6 citations

Preparation of protein-protein conjugates and some novel polyamino acid derivatives employing a bifunctional reagent

1963 • 5 citations

Chemische Modifizierung von Insulin, Seidenfibroin, Sehnenkollagen und Wollkeratin mit Nitrophenylestern

1963 • 5 citations