7 Schiff Base Intermediates in Enzyme Catalysis

Catalysis in chemistry and enzymology

1969 • 3,236 citations

Modern Synthetic Reactions

1972 • 1,443 citations

Chemistry of the metal chelate compounds

1953 • 1,006 citations

A General Mechanism for Vitamin B₆-catalyzed Reactions¹

1954 • 627 citations

The Chemistry of the carbonyl group

1966 • 479 citations

Glutamic Aspartic Transaminase

1959 • 368 citations

A Kinetic and Equilibrium Analysis of the Glutamic Oxaloacetate Transaminase Mechanism

1962 • 348 citations

δ-AMINOLEVULINIC ACID, ITS ROLE IN THE BIOSYNTHESIS OF PORPHYRINS AND PURINES¹

1953 • 339 citations

Chemical Structure in Relation to Biological Activities of Vitamin B6

1958 • 289 citations

THE REACTION OF SODIUM BOROHYDRIDE WITH MUSCLE PHOSPHORYLASE¹

1958 • 283 citations

Spectra and Ionization Constants of the Vitamin B₆ Group and Related 3-Hydroxypyridine Derivatives¹

1955 • 283 citations

CRYSTALLINE ALDOLASE

1948 • 275 citations

Some Transamination Reactions Involving Vitamin B₆¹

1952 • 245 citations

Equilibria between Pyridoxal and Amino Acids and their Imines¹

1957 • 224 citations

δ-Aminolevulinic Acid Dehydratase of Rhodopseudomonas spheroides

1968 • 214 citations

A CRYSTALLINE ENZYME THAT CLEAVES HOMOSERINE AND CYSTATHIONINE

1958 • 212 citations

Kinetic Studies of Glutamic Oxaloacetic Transaminase Isozymes^*

1964 • 198 citations

The Purification and Characterization of O-Acetylserine Sulfhydrylase-A from Salmonella typhimurium

1969 • 197 citations

Properties of Crystalline Tryptophanase

1965 • 195 citations

On the Role of Pyridoxal 5'-Phosphate in Phosphorylase. II. Resolution of Rabbit Muscle Phosphorylase b^*

1966 • 180 citations

The Relation of Spectral Changes and Tritium Exchange Reactions to the Mechanism of Tryptophanase-catalyzed Reactions

1967 • 178 citations

Enzymatic Transamination of Pyridoxamine

1962 • 158 citations

The Vitamin B₆ Group. V. The Reversible Interconversion of Pyridoxal and Pyridoxamine by Transamination Reactions

1945 • 149 citations

Modern synthetic reactions

1965 • 146 citations

δ-Aminolevulinic Acid Dehydratase of Rhodopseudomonas spheroides

1968 • 144 citations

CATALYTIC PROPERTIES OF TRYPTOPHANASE, A MULTIFUNCTIONAL PYRIDOXAL PHOSPHATE ENZYME

1964 • 141 citations

The molecular weights of some crystalline enzymes from muscle and yeast I. Aldolase and d-glyceraldehyde-3-phosphate dehydrogenase

1956 • 138 citations

DEAMINATION OF SERINE

1952 • 137 citations

The Reversible Catalytic Cleavage of Hydroxyamino Acids by Pyridoxal and Metal Salts¹

1954 • 129 citations

Arginine Decarboxylase from Escherichia coli

1968 • 128 citations

Monoamine Oxidase

1962 • 126 citations

Purification and Properties of the B Component of Escherichia coli Tryptophan Synthetase

1965 • 125 citations

The Subunit Structure of Tryptophanase

1967 • 124 citations

Histidine decarboxylase of Lactobacillus 30a. IV. The presence of covalently bound pyruvate as the prosthetic group

1968 • 124 citations

Benzylamine oxidase and histaminase: purification and crystallization of an enzyme from pig plasma

1964 • 115 citations

Serine Transhydroxymethylase

1963 • 113 citations

Alanine Aminotransferase

1967 • 108 citations

Catalytic Racemization of Amino Acids by Pyridoxal and Metal Salts

1952 • 107 citations

Biosynthesis of Sphingolipid Bases

1968 • 106 citations

Pyridoxine and Pyridoxal Analogs. VI. Electronic Absorption Spectra of Schiff Bases

1963 • 105 citations

Structure of the binding site of pyridoxal 5'-phosphate to Escherichia coli glutamate decarboxylase

1970 • 99 citations

Threonine Deaminase from Salmonella typhimurium

1968 • 98 citations

STUDIES ON THE COENZYME ACTIVATION OF GLUTAMIC-ASPARTIC APOTRANSAMINASE

1954 • 96 citations

Glutamic Aspartic Transaminase

1959 • 95 citations

Mechanism of Action of Transaldolase

1961 • 93 citations

ON THE MECHANISM OF THE ENZYMATIC DECARBOXYLATION OF ACETOACETATE¹

1959 • 91 citations

d-Alanine-d-Glutamate Transaminase

1965 • 91 citations

Glutamic-Aspartic Transaminase

1966 • 90 citations

On the Mechanism of the Enzymatic Decarboxylation of Acetoacetate. II

1962 • 89 citations

Cystathionine γ-Synthetase of Salmonella

1966 • 89 citations

Bovine Liver Aldolase

1958 • 88 citations

Serine Transhydroxymethylase: Spectral Properties of the Enzyme-bound Pyridoxal-5-phosphate

1962 • 87 citations

Histidine decarboxylase of Lactobacillus 30a. II. Purification, substrate specificity, and stereospecificity

1968 • 86 citations

Purification and properties of rat muscle glycogen phosphorylase

1969 • 83 citations

Histidine decarboxylase of Lactobacillus 30a. VI. Mechanism of action and kinetic properties

1970 • 82 citations

Acetoacetate Decarboxylase. Identification of Lysine at the Active Site^*

1966 • 82 citations

Identification of α-Ketobutyrate as the Prosthetic Group of Urocanase from Pseudomonas putida

1970 • 82 citations

Glutamic-Aspartic Transaminase

1964 • 81 citations

A Kinetic Study of the Reaction Mechanism of Tryptophanase-catalyzed Reactions

1967 • 80 citations

The Subunit Structure of Tryptophanase

1967 • 77 citations

Enzymatic Transamination of Pyridoxamine

1962 • 76 citations

The Effect of Solvent on Some Reaction Rates

1941 • 76 citations

Threonine Synthetase Mechanism: Studies with Isotopic Hydrogen

1960 • 76 citations

The Comparative Activities of Metal Ions in Promoting Pyridoxal-catalyzed Reactions of Amino Acids¹

1957 • 75 citations

Monoamine Oxidase

1963 • 74 citations

Arginine Decarboxylase from Escherichia coli

1968 • 73 citations

Conformational changes and the mechanism of resolution of glycogen phosphorylase

1969 • 72 citations

Purification and Properties of d-Serine Dehydrase from Escherichia coli

1966 • 72 citations

The chemistry of carbonyl compounds

1967 • 71 citations

Chemical and physical properties of Escherichia coli glutamate decarboxylase

1970 • 67 citations

Imidazolylacetolphosphate: l-Glutamate Aminotransferase

1967 • 65 citations

δ-Aminolevulinic Acid Dehydratase of Rhodopseudomonas spheroides

1968 • 63 citations

L-lysine-.alpha.-ketoglutarate aminotransferase. II. Purification, crystallization, and properties

1968 • 63 citations

Stereochemistry of enzymic transamination

1968 • 62 citations

Pyridoxal-Catalyzed Decarboxylation of Amino Acids^*

1962 • 61 citations

Pyridoxal phosphate as a constituent of the histaminase (benzylamine oxidase) of pig plasma

1965 • 61 citations

Purification and properties of histidine decarboxylase from Lactobacillus 30a.

1965 • 60 citations

Rat Liver Alanine Aminotransferase

1968 • 58 citations

Stereochemistry of transamination catalyzed by pyridoxamine-pyruvate transaminase

1968 • 58 citations

ON THE NATURE OF THE TRANSLDOLASE-DIHYDROXYACETONE COMPLEX

1961 • 56 citations

Kinetic investigation of the interaction of erythro-β-hydroxyaspartic acid with aspartate aminotransferase

1969 • 55 citations

The Mechanism of Action of Aldolases

1965 • 54 citations

Primary structure of pyridoxal phosphate binding site in the mitochondrial and extramitochondrial aspartate aminotransferases from pig heart muscle. Chymotryptic peptides

1969 • 54 citations

The Amine Catalysis of the Dealdolization of Diacetone Alcohol

1938 • 52 citations

The Presence of Covalently Bound Pyruvate in d-Proline Reductase and Its Participation in the Catalytic Process

1967 • 51 citations

The Mechanism of Action of 5'-Adenylic Acid-activated Threonine Dehydrase

1968 • 51 citations

Subunit structure of the B component of Escherichia coli tryptophan synthetase

1969 • 51 citations

REVERSIBLE CATALYTIC CLEAVAGE OF HYDROXYAMINO ACIDS BY PYRIDOXAL AND METAL SALTS

1953 • 50 citations

Biosynthesis of Sphingolipid Bases

1969 • 48 citations

The Chemical Structure of Tryptophanase from Escherichia coli

1970 • 48 citations

Imidazolylacetolphosphate: l-Glutamate Aminotransferase

1967 • 48 citations

Studies on the Interaction between Regulatory Enzymes and Effectors

1969 • 48 citations

4-Hydroxy-2-ketoglutarate Aldolase of Rat Liver

1967 • 47 citations

Purification and Properties of an α-Dialkyl Amino Acid Transaminase^*

1967 • 45 citations

The Active Site of Acetoacetate Decarboxylase¹

1966 • 45 citations

Formation of α-Ketoglutaric Semialdehyde from l-2-Keto-3-deoxyarabonic Acid and Isolation of l-2-Keto-3-deoxyarabonate Dehydratase from Pseudomonas saccharophila

1966 • 45 citations

The Mechanism of Action of Aldolases

1965 • 45 citations

On the mechanism of action of glutamic-aspartic transaminase: Intermediate steps in the reaction

1960 • 44 citations

Studies on the Mechanism of Action of 2-Keto-3-deoxy-l-arabonate Dehydratase

1967 • 44 citations

Effects of various vitamin B₆ 5'-phosphate derivatives on the structure and activities of L-aspartate β-decarboxylase

1969 • 44 citations

Threonine Deaminase of Clostridium tetanomorphum

1966 • 41 citations

Acetoacetate Decarboxylase. Preparation of the Enzyme^*

1966 • 41 citations

Sulfhydryl groups of L-aspartate β-decarboxylase

1968 • 40 citations

Mechanism of action of pyridoxamine pyruvate transaminase

1968 • 39 citations

Catalytic Reactions Involving Azomethines. I. The Imidazole Catalysis of the Transamination of Pyridoxal by α-Aminophenylacetic Acid

1963 • 39 citations

Crystallization and Characteristics of 2-Keto-3-deoxy-6-phosphogluconic Aldolase

1964 • 39 citations

Metal Chelates of Imines Derived from Pyridoxal and Amino Acids¹

1961 • 39 citations

Pyridoxal Catalysis of Non-enzymatic Transamination in Ethanol Solution¹

1957 • 39 citations

Amine Catalysis of the Ketonic Decomposition of α,α-Dimethylacetoacetic Acid

1938 • 38 citations

An Intermediate Trapped by Maleimides in a Pyridoxal-Phosphate Potentiated Enzymatic Elimination Reaction

1964 • 38 citations

Stereochemistry of The Manganese(II)-Pyridoxylidenevaline Chelate

1963 • 37 citations

Crystalline d-Serine Dehydrase

1966 • 37 citations

The Mechanism of Action of Aldolases

1965 • 37 citations

Enzymic Reactions of Enamines with N-Ethylmaleimide

1969 • 34 citations

Oxidative Deamination of Amino Acids by Pyridoxal and Metal Salts¹

1954 • 34 citations

Acetoacetate decarboxylase. Reaction with acetopyruvate

1968 • 33 citations

Catalytic Reactions Involving Azomethines. VI. The Mechanism of the Transamination of 3-Hydroxypyridine-4-aldehyde by Glutamic Acid^*

1965 • 33 citations

Relation of structure to activity of pyridoxal analogs as substrates for pyridoxamine-pyruvate transaminase

1968 • 33 citations

Mechanism of Binding of Pyridoxamine 5-Phosphate to the Apoenzyme Aspartate Aminotransferase

1969 • 32 citations

Electronic aspects of the reactions of pyridoxal phosphate enzymes

1961 • 31 citations

Equilibria and solute structures in the aqueous systems pyridoxal-alanine-zinc(II) and -aluminum(III) as investigated by proton resonance

1969 • 31 citations

Coenzymatic activity of homologues of pyridoxal phosphate.

1967 • 31 citations

THE PREPARATION OF CRYSTALLINE TRANSALDOLASE FROM CANDIDA UTILIS

1961 • 31 citations

Regulation and subunit structure of aspartate β-decarboxylase. Enzymes from Alcaligenes faecalis and Pseudomonas dacunhae

1970 • 30 citations

Pyridoxal Derivatives in Transamination

1952 • 30 citations

Electrophoretic and chromatographic study of some chemical transamination reactions involving vitamin B6

1957 • 29 citations

Enzymatic Elimination from a Substituted Four-Carbon Amino Acid Coupled to Michael Addition of a β-Carbon to an Electrophilic Double Bond. Structure of the Reaction Product^*

1966 • 28 citations

Purification and Some Properties of Tryptophanase from Bacillus alvei^*

1966 • 27 citations

On the Mechanism of Activation of l-Threonine Deaminase from Clostridium tetanomorphum by Adenosine Diphosphate

1967 • 27 citations

[125] Oxalacetic carboxylase of Micrococcus lysodeikticus

1955 • 26 citations

Acetoacetate decarboxylase. Catalysis of hydrogendeuterium exchange in acetone

1968 • 26 citations

Threonine Deaminase of Clostridium tetanomorphum

1966 • 26 citations

[91] 2-Keto-3-deoxy-6-phosphogluconic aldolase (crystalline)

1966 • 26 citations

Subunit structure of L-aspartate β-decarboxylase from Alcaligenes faecalis

1970 • 25 citations

Oxidation by Molecular Oxygen. IV. A Possible Model Reaction for Some Amine Oxidases^1-3

1966 • 25 citations

Crystalline L-Aspartate β-Decarboxylase of Pseudomonas dacunhae

1969 • 25 citations

Oxalacetate decarboxylase from cod. Mechanism of action and stereoselective reduction of pyruvate by borohydride

1968 • 25 citations

Acetoacetate Decarboxylase. Subunits and Properties^*

1966 • 24 citations

Molecular weight and subunit structure of pyridoxamine pyruvate transaminase

1968 • 23 citations

Eigenschaften einer Oxalacetat-Decarboxylase aus Dorschmuskulatur

1966 • 22 citations

Threonine Biosynthesis

1965 • 22 citations

METAL-CHELATED PYRIDOXYLIDENE DERIVATIVES OF GLYCINE AND α,γ-DIAMINOBUTYRIC ACID

1956 • 22 citations

The formation of an enzyme-bound β-carbanion in the enzymic conversion of l-homoserine to α-ketobutyrate

1968 • 21 citations

Aminomalonic Decarboxylase^*

1962 • 19 citations

Physical and Catalytic Properties of Tryptophanase from Bacillus alvei^*

1966 • 19 citations

Proton retention in the γ-elimination reaction catalysed by cystathionine γ-synthase

1968 • 18 citations

THE CLEAVAGE OF α-METHYLSERINE AND α-METHYLOLSERINE BY PYRIDOXAL AND METAL IONS

1957 • 18 citations

Kinetics of the Amino Acid-catalyzed Dealdolization of Diacetone Alcohol¹

1957 • 12 citations

Cupric Chelates of Pyridoxylvaline and Pyridoxylidenevaline¹

1959 • 6 citations

[Isolation of a coenzyme-quasisubstrate complex from aspartate-glutamate-transaminase].

1965 • 4 citations