Interaction of C1q and Mannan-Binding Lectin (MBL) with C1r, C1s, MBL-Associated Serine Proteases 1 and 2, and the MBL-Associated Protein MAp19

The use of avidin-biotin interaction in immunoenzymatic techniques.

1979 • 1,734 citations

A second serine protease associated with mannan-binding lectin that activates complement

1997 • 827 citations

Mannose-binding lectin: the pluripotent molecule of the innate immune system

1996 • 727 citations

Activation of the classical complement pathway by mannose-binding protein in association with a novel C1s-like serine protease.

1992 • 646 citations

The CUB Domain

1993 • 564 citations

ASSOCIATION OF LOW LEVELS OF MANNAN-BINDING PROTEIN WITH A COMMON DEFECT OF OPSONISATION

1989 • 509 citations

Serum lectin with known structure activates complement through the classical pathway.

1987 • 432 citations

Association of mutations in mannose binding protein gene with childhood infection in consecutive hospital series

1997 • 371 citations

Binding of the pentamer/hexamer forms of mannan-binding protein to zymosan activates the proenzyme C1r2C1s2 complex, of the classical pathway of complement, without involvement of C1q.

1990 • 332 citations

Cutting Edge: Complement-Activating Complex of Ficolin and Mannose-Binding Lectin-Associated Serine Protease

2000 • 325 citations

Purification and radiolabeling of human C1q.

1981 • 295 citations

Characterization studies on a new lectin found in seeds of Vicia ervilia

1975 • 275 citations

Isolation and characterization of C1q, a subcomponent of the first component of complement, from human and rabbit sera

1972 • 272 citations

Characterization of the Carbohydrate Fragments Obtained from Saccharomyces cerevisiae Mannan by Alkaline Degradation

1974 • 241 citations

Two Constituents of the Initiation Complex of the Mannan-Binding Lectin Activation Pathway of Complement Are Encoded by a Single Structural Gene

1999 • 209 citations

Mannose-binding lectin: the pluripotent molecule of the innate immune system

1996 • 205 citations

A truncated form of mannose-binding lectin-associated serine protease (MASP)-2 expressed by alternative polyadenylation is a component of the lectin complement pathway

1999 • 193 citations

The mechanism of carbohydrate-mediated complement activation by the serum mannan-binding protein.

1990 • 181 citations

Distinct physicochemical characteristics of human mannose binding protein expressed by individuals of differing genotype.

1995 • 181 citations

Mannan‐Binding Lectin Deficiency is Associated with Unexplained Recurrent Miscarriage

1999 • 111 citations

Improvements on the purification of mannan-binding lectin and demonstration of its Ca2+-independent association with a C1s-like serine protease

1996 • 97 citations

DEFICIENCY OF C1r IN HUMAN SERUM

1970 • 90 citations

The level of mannan-binding protein regulates the binding of complement-derived opsonins to mannan and zymosan at low serum concentrations

1990 • 90 citations

Activation of the C4 and C2 components of complement by a proteinase in serum bactericidal factor, Ra reactive factor.

1993 • 72 citations

Human serum mannose-binding lectin (MBL)-associated serine protease-1 (MASP-1): determination of levels in body fluids and identification of two forms in serum

1997 • 70 citations

Amino-terminal calcium-binding domain of human complement C1.hivin.s mediates the interaction of C1.hivin.r with C1q

1990 • 61 citations

C1 SUBCOMPONENT COMPLEXES IN NORMAL AND PATHOLOGICAL SERA STUDIED BY CROSSED IMMUNOELECTROPHORESIS

1976 • 59 citations

The distortive mechanism for the activation of complement component C1 supported by studies with a monoclonal antibody against the “arms” of C1q

1988 • 57 citations

[4] The human complement system serine proteases and and their proenzymes

1981 • 54 citations

A Rainbow Trout Lectin with Multimeric Structure

1997 • 51 citations

Recognition of complex carbohydrates by Ca2+-dependent animal lectins

1993 • 51 citations

Structure and biology of mannan-binding protein, MBP, an important component of innate immunity

1999 • 49 citations

Mannan-binding protein, a complement activating animal lectin

1992 • 45 citations

A study on the structure and interactions of the C1 sub-components C1r and C1s in the fluid phase

1980 • 38 citations

Localization of rat CD1 transcripts and protein in rat tissues—an analysis of rat CD1 expression by in situ hybridization and immunohistochemistry

1997 • 38 citations

Activation of human complement serine-proteinase C1r is down-regulated by a Ca2+-dependent intramolecular control that is released in the C1 complex through a signal transmitted by C1q

1994 • 34 citations

Dissociation of C1 and concentration dependence of its activation kinetics

1982 • 28 citations

Structural and Functional Studies on C1r and C1s: New Insights into the Mechanisms Involved in C1 Activity and Assembly

1998 • 16 citations

Glycosphingolipid-binding specificity of the mannose-binding protein from human sera

1990 • 13 citations

Nature of the interaction between the C1q and C1r2s2 subunits of the first component of human complement

1985 • 11 citations