Escherichia coli exports previously folded and biotinated protein domains

Experiments in molecular genetics

1972 • 28,260 citations

Polypeptide chain binding proteins: Catalysts of protein folding and related processes in cells

1989 • 884 citations

Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria

1986 • 723 citations

Interposon mutagenesis of soil and water bacteria: a family of DNA fragments designed for in vitro insertional mutagenesis of Gram-negative bacteria

1987 • 700 citations

Biotination of proteins in vivo. A post-translational modification to label, purify, and study proteins.

1990 • 402 citations

Characterization of degP, a gene required for proteolysis in the cell envelope and essential for growth of Escherichia coli at high temperature

1989 • 375 citations

An Escherichia coli mutation preventing degradation of abnormal periplasmic proteins.

1988 • 374 citations

Evidence for specificity at an early step in protein export in Escherichia coli

1985 • 272 citations

Evolutionary conservation among biotin enzymes.

1988 • 266 citations

Effects of mutations in heat-shock genes groES and groEL on protein export in Escherichia coli.

1989 • 250 citations

Modulation of Folding Pathways of Exported Proteins by the Leader Sequence

1988 • 243 citations

Fusions of secreted proteins to alkaline phosphatase: an approach for studying protein secretion.

1985 • 238 citations

Unity in Function in the Absence of Consensus in Sequence: Role of Leader Peptides in Export

1989 • 222 citations

Murein-lipoprotein of Escherichia coli: A protein involved in the stabilization of bacterial cell envelope

1978 • 179 citations

The E. coli bio operon: Transcriptional repression by an essential protein modification enzyme

1989 • 175 citations

Heat-shock proteins DnaK and GroEL facilitate export of LacZ hybrid proteins in E. coli

1990 • 175 citations

The role of the beta-lactamase signal sequence in the secretion of proteins by Escherichia coli.

1984 • 128 citations

Escherichia coli SecB protein associates with exported protein precursors in vivo.

1989 • 123 citations

ProOmpA contains secondary and tertiary structure prior to translocation and is shielded from aggregation by association with SecB protein.

1990 • 114 citations

The sodium ion translocating oxalacetate decarboxylase of Klebsiella pneumoniae. Sequence of the biotin-containing alpha-subunit and relationship to other biotin-containing enzymes.

1988 • 97 citations

Conformational Flexibility and Folding of Synthetic Peptides Representing an Interdomain Segment of Polypeptide Chain in the Pyruvate Dehydrogenase Multienzyme Complex of Escherichia coli

1989 • 83 citations

Preprotein conformation: the year's major theme in translocation studies

1988 • 63 citations

The acylated precursor form of the colicin A lysis protein is a natural substrate of the DegP protease

1989 • 51 citations

Acetyl Coenzyme A Carboxylase

1973 • 50 citations

Mutagenesis affecting the carboxyl terminus of the biotinyl subunit of transcarboxylase. Effects on biotination.

1987 • 41 citations

Comparison of the biotination of apotranscarboxylase and its aposubunits. Is assembly essential for biotination?

1980 • 23 citations

Insertional restoration of β-galactosidase α-complementation (white-to-blue colony screening) facilitates assembly of synthetic genes

1988 • 19 citations

Engineered gene forEscherichia colialkaline phosphatase for the construction of translational fusions

1990 • 15 citations