Gamma-Glutamyltransferase and Other Markers for Alcoholism

The Michigan Alcoholism Screening Test: The Quest for a New Diagnostic Instrument

1971 • 3,492 citations

The CAGE Questionnaire: Validation of a New Alcoholism Screening Instrument

1974 • 2,274 citations

HISTOCHEMICAL AND ULTRASTRUCTURAL DEMONSTRATION OF γ-GLUTAMYL TRANSPEPTIDASE ACTIVITY

1969 • 940 citations

On the Enzymology of Amino Acid Transport

1973 • 637 citations

Isolation of γ-Glutamyl Transpeptidase from Hog Kidney

1965 • 459 citations

COMPARISON OF QUESTIONNAIRE AND LABORATORY TESTS IN THE DETECTION OF EXCESSIVE DRINKING AND ALCOHOLISM

1982 • 456 citations

Serum γ-glutamyl transpeptidase activity in alcoholism

1972 • 416 citations

Biochemistry and Pharmacology of Ethanol

1979 • 353 citations

Ethanol-Induced Hyperuricemia

1982 • 319 citations

MEAN CELL VOLUME AND GAMMA-GLUTAMYL-TRANSPEPTIDASE AS MARKERS OF DRINKING IN WORKING MEN

1981 • 232 citations

The evolution of anemia in alcoholic patients

1971 • 228 citations

Correlation of Folate Deficiency with Alcoholism and Associated Macrocytosis, Anemia, and Liver Disease

1963 • 215 citations

BIOCHEMICAL AND HqMATOLOGICAL MARKERS OF ALCOHOL INTAKE

1978 • 204 citations

Rat liver canalicular membrane vesicles. Isolation and topological characterization.

1983 • 202 citations

Serum gamma glutamyl transpeptidase in relation to alcohol consumption

1972 • 193 citations

CYTOCHEMICAL LOCALIZATION OF 5'-NUCLEOTIDASE IN SUBCELLULAR FRACTIONS ISOLATED FROM RAT LIVER

1972 • 193 citations

MACROCYTOSIS OF CHRONIC ALCOHOLISM

1974 • 191 citations

Clinical Significance of Abnormal Heterogeneity of Transferrin in Relation to Alcohol Consumption

1979 • 186 citations

Alterations of lipid metabolism in healthy volunteers during long‐term ethanol intake

1977 • 182 citations

Aspartate aminotransferase activity and isoenzyme proportions in human liver tissues.

1978 • 178 citations

Abnormal Microheterogeneity of Transferrin in Serum and Cerebrospinal Fluid in Alcoholism

1978 • 150 citations

Induction of hepatic microsomal gamma-glutamyltransferase activity following chronic alcohol consumption

1977 • 147 citations

Alcohol, protein metabolism, and liver injury

1980 • 145 citations

Structural carbohydrates in the liver

1984 • 141 citations

Is serum gamma-glutamyltransferase a misleading test?

1983 • 139 citations

Serum Activity of Mitochondrial Aspartate Aminotransferase: A Sensitive Marker of Alcoholism With or Without Alcoholic Hepatitis

1984 • 139 citations

Evidence of a Reduced Sialic Acid Content in Serum Transferrin in Male Alcoholics

1981 • 126 citations

Glutamate dehydrogenase: a reliable marker of liver cell necrosis in the alcoholic.

1977 • 120 citations

The Diagnosis of Alcoholism in a Psychiatric Hospital: A Trial of the Michigan Alcoholism Screening Test (MAST)

1972 • 111 citations

Plasma amino acid abnormalities in the alcoholic

1978 • 103 citations

Quantitative estimation of abnormal microheterogeneity of serum transferrin in alcoholics

1980 • 102 citations

Cell surface distribution and intracellular fate of asialoglycoproteins: a morphological and biochemical study of isolated rat hepatocytes and monolayer cultures

1982 • 99 citations

Immunocytochemical localization of the receptor for asialoglycoprotein in rat liver cells.

1982 • 98 citations

Biochemical and Hematologic Correlates of Alcoholism and Liver Disease

1982 • 97 citations

Biochemical Markers for Alcoholism

1984 • 97 citations

Red blood cell mean corpuscular volume: a potential indicator of alcohol usage in a working population

1974 • 92 citations

Folate Deficiency in Chronic Liver Disease

1965 • 90 citations

Identification and quantification of the rat hepatocyte asialoglycoprotein receptor.

1981 • 88 citations

The Nature and Origin of Proliferated Bile Ductules in Alcoholic Liver Disease

1983 • 84 citations

Elevated serum gamma-glutamyl-transferase (transpeptidase) and histological liver damage in alcoholism.

1976 • 81 citations

Receptor-rich intracellular membrane vesicles transporting asialotransferrin and insulin in liver

1982 • 81 citations

Observations on the site of origin of serum γ-glutamyl-transpeptidase

1969 • 76 citations

Plasma Alpha Amino- n -Butyric Acid to Leucine Ratio: An Empirical Biochemical Marker of Alcoholism

1976 • 76 citations

Enzyme changes in experimental biliary obstruction

1973 • 69 citations

Biliary protein output by isolated perfused rat livers. Effects of bile salts

1983 • 64 citations

Localization of gamma-glutamyltransferase in subcellular fractions of rat and rabbit liver: Effect of phenobarbital

1979 • 64 citations

Diagnosis of alcoholism with a self-administered alcoholism screening test: results with 1,002 consecutive patients receiving general examinations.

1980 • 64 citations

Liver in metabolic diseases

1984 • 63 citations

Macrocytosis in alcohol-related liver disease: its value for screening

1981 • 61 citations

Biochemical and haematological indicators of excessive alcohol consumption.

1981 • 61 citations

Hepatic and intestinal gamma-glutamyltranspeptidase activity: Its activation by chronic ethanol administration

1978 • 60 citations

Elevation of the Hemoglobin Al Fraction in Alcoholism

1982 • 60 citations

Relations between reported alcohol consumption and certain biological variables in an "unselected" population.

1979 • 59 citations

Hepatic gamma-glutamyltransferase activity in alcoholic fatty liver: comparison with other liver enzymes in man and rats.

1983 • 59 citations

Fractures on the chest radiograph in detection of alcoholic liver disease.

1982 • 59 citations

Screening Tests for Alcoholism - Findings from a Community Study

1980 • 57 citations

Ethanol Effects in a Rat Hepatoma Cell Line: Induction of γ -Glutamytransferase

1983 • 53 citations

Biochemical Diagnosis of Alcoholism

1981 • 53 citations

β-Hexosaminidase, leucine aminopeptidase, cystidyl aminopeptidase, hepatic enzymes and bilirubin in serum of chronic alcoholics with acute ethanol intoxication

1980 • 53 citations

Determination of aspartate aminotransferase isoenzymes in hepatic diseases — preliminary findings

1983 • 52 citations

Biliary Proteins

1984 • 51 citations

Purification and some properties of γ-glutamyltransferase from human liver

1977 • 49 citations

Effect of chronic alcohol consumption on the activities of liver plasma membrane enzymes: Gamma-glutamyltransferase, alkaline phosphatase and 5'-nucleotidase

1982 • 49 citations

Biochemical and hematological correlates of alcoholism.

1980 • 48 citations

Relationship between blood lactic acid and serum proline in alcoholic liver cirrhosis

1981 • 47 citations

Membrane traffic at the hepatocyte's sinusoidal and canalicular surface domains

1981 • 46 citations

Ratio of Plasma Alpha Amino- n -Butyric Acid to Leucine as an Empirical Marker of Alcoholism: Diagnostic Value

1977 • 44 citations

Relations between reported alcohol consumption and certain biological variables in an "unselected" population.

1979 • 44 citations

Serum Cholic and Chenodeoxycholic Acid Conjugates and Standard Liver Function Tests in Various Morphological Stages of Alcoholic Liver Disease

1980 • 40 citations

Increased hepatic production of alpha-amino-n-butyric acid after chronic alcohol consumption in rats and baboons

1980 • 39 citations

Biochemical Tests for the Detection of Alcoholism: Comparison of Plasma Alpha‐Amino‐n‐Butyric Acid with Other Available Tests

1978 • 39 citations

Subcellular localization of 7-glutamyltransferase activity in guinea pig liver. Effect of phenobarbital on the enzyme activity levels

1979 • 39 citations

The effects of ethanol (0.75 g/kg body weight) on the activities of selected enzymes in sera of healthy young adults: 1. Intermediate-term effects.

1977 • 38 citations

Detection of Alcoholism Relapse: Comparative Diagnostic Value of MCV, GGTP, and AANB

1979 • 37 citations

Elevated Liver Gamma-Glutamyl Transferase in Chronic Alcoholics

1980 • 36 citations

Hepatic microsomal drug metabolism, glutamyl transferase activity and in vivo antipyrine half-life in rats chronically fed an ethanol diet, a control diet and a chow diet.

1980 • 36 citations

Sex-related differences in the haematological effects of excessive alcohol consumption.

1980 • 36 citations

Enzyme Activities of Cells of Different Types Isolated from Livers of Normal and Cholestatic Rats

1977 • 36 citations

An immunochemical procedure for determination of mitochondrial aspartate aminotransferase in human serum.

1980 • 36 citations

γ-Glutamyl transpeptidase activity in liver disease: serum elevation is independent of hepatic GGTP activity

1982 • 36 citations

Gamma-glutamyltransferase activity of liver plasma membrane: Induction following chronic alcohol consumption

1981 • 35 citations

Induction and ‘Superinduction’ of Sialylation of Membrane‐Bound γ‐Glutamyltransferase during Liver Regeneration

1978 • 35 citations

Plasma α-Amino-n-Butyric Acid to Leucine Ratio

1978 • 34 citations

Does chronic alcohol consumption really induce hepatic microsomal gamma-glutamyltransferase activity?

1977 • 33 citations

Oesophageal Lesions in the Alcoholic

1981 • 31 citations

Hepatic receptor for asialo-glycoproteins Ultrastructural demonstration of ligand-induced microaggregation of receptors

1981 • 30 citations

Acute biochemical responses to moderate beer drinking.

1982 • 30 citations

Liver and Bile

1932 • 29 citations

Depression of Erythrocyte δ-Aminolaevulinic Acid Dehydratase Activity in Alcoholics

1974 • 28 citations

Biochemical diagnosis of alcoholism. A test of the discriminating capabilities of gamma-glutamyl transpeptidase and mean corpuscular volume

1981 • 28 citations

Neue Ergebnisse zur biologischen und medizinischen Bedeutung von Glycoproteinen

1979 • 27 citations

The effects of ethanol (0.75 g/kg body weight) on the activities of selected enzymes in sera of healthy young adults: 1. Intermediate-term effects.

1977 • 27 citations

γ-Glytamyltransferase of rabbit liver: Kinetic study of phenobarbital induction and in vitro solubilization by bile salts

1980 • 27 citations

Histochemistry of γ-Glutamyl Transpeptidase in Human Liver Biopsies

1981 • 27 citations

Isoenzymdifferenzierung der Gamma-Glutamyltransferase mit Concanavalin A und Con A-Sepharose

1976 • 26 citations

Hepatic gamma-glutamyltransferase activity: Its increase following chronic alcohol consumption and the role of carbohydrates

1982 • 25 citations

Effect of Prednisolone on Anaemia Associated with Macroglobulinaemia

1958 • 25 citations

Histochemical Study of So-called “Marker Enzymes of Cholestasis” During Extrahepatic Bile Duct Obstruction in the Rat

1973 • 24 citations

Biochemical and hematologic correlates of alcoholism and liver disease

1982 • 24 citations

Glycoproteins: Their biological and clinical significance. II

1979 • 24 citations

Serum glutamate dehydrogenase is not a reliable marker of liver cell necrosis in alcoholics.

1982 • 23 citations

Effect of Chronic Ethanol Administration on Gamma-Glutamyltransferase Activities in Plasma and in Hepatic Plasma Membranes of Male and Female Rats

1982 • 23 citations

The effect of neuraminidase on the properties of γ-glutamyl transpeptidase

1964 • 23 citations

Plasma Glutamate Dehydrogenase: Clinical Application in Patients With Alcoholic Liver Disease

1980 • 22 citations

Plasma alpha amino-n-butyric acid: leucine ratio. Normal values in alcoholics.

1978 • 21 citations

Alcohol and gamma-glutamyltransferase

1983 • 20 citations

Serum Ethanol, Hepatic Enzymes and Length of Debauch in Chronic Alcoholics

1979 • 19 citations

Effects of ethanol (0.75 g/kg body weight) on the activities of selected enzymes in sera of healthy young adults: 2. Interindividual variations in response of gamma-glutamyltransferase to repeated ethanol challenges.

1977 • 19 citations

Alcoholic Liver Disease Associated with Increased Gamma-Glutamyltransferase Activities in Serum and Liver

1980 • 19 citations

Effect of an intravenous infusion of ethanol on serum enzymes and lipids in patients with alcoholic liver disease

1980 • 18 citations

Influence of taurocholate on hepatic clearance and biliary excretion of asialo intestinal alkaline phosphatase in the rat in vivo and in isolated perfused rat liver

1983 • 18 citations

Estimation of Alcohol Intake from Laboratory Results

1978 • 17 citations

The Use of a Combination of Peripheral Markers for Diagnosing Alcoholism and Monitoring for Continued Abuse

1981 • 17 citations

Serum glutamate dehydrogenase as a marker of hepatocyte necrosis in alcoholic liver disease.

1981 • 16 citations

Changes in Hepatic Enzymes and Organelles in Alcoholic Liver Disease

1978 • 16 citations

Drivers, binge drinking, and gammaglutamyltranspeptidase.

1982 • 16 citations

Studies on the Subcellular Localization of γ-Glutamyl Transpeptidase in Rat Liver

1978 • 16 citations

Significance of Increased Serum Gamma-Glutamyltransferase Activity during Long-Term Anticonvulsive Treatment. Clinical and Experimental Studies^1,2

1975 • 16 citations

Serum Folate and B12 and Haematological Status of In‐patient Alcoholics

1978 • 16 citations

Mechanism of increased gamma glutamyl transpeptidase after chronic alcohol consumption: hepatic microsomal induction rather than dietary imbalance.

1980 • 15 citations

Alkoholtoxische Veränderungen der Hämatopoiese

1981 • 15 citations

Asialoglycoprotein receptor is uninvolved in clearing intact glycoproteins from rat blood

1983 • 14 citations

Enhanced serum glutamic oxaloacetic transaminase activity of mitochondrial origin in chronic alcoholics.

1979 • 14 citations

Effects of ethanol (0.75 g/kg body weight) on the activities of selected enzymes in sera of healthy young adults: 2. Interindividual variations in response of gamma-glutamyltransferase to repeated ethanol challenges.

1977 • 14 citations

Gamma Glutamyl Transferase

1978 • 13 citations

Analytical Subcellular Fractionation Studies on Different Cell Types Isolated from Normal Rat Liver

1978 • 13 citations

The activity of gamma-glutamyl transpeptidase in the serum of problem drinkers.

1978 • 13 citations

Forensic considerations on the comparison of “serum γ-glutamyltranspeptidase” (“γ-GT”) activity in experimental acute alcoholic intoxication and in alcoholic car drivers who caused road accidents

1978 • 12 citations

Biochemical and Histochemical Estimations of Liver γ-Glutamyltransferase Activity in Ethanol-Fed Rats

1980 • 12 citations

Microassay of gamma-glutamyl transpeptidase in needle biopsies of human liver.

1980 • 11 citations

Gamma glutamyl transferase: application of a new radiochemical assay to the analysis of its subcellular distribution in the rat liver.

1978 • 10 citations

Effect of Ca2+, Mg2+, NaN3, cholinergic agents, and gastrointestinal hormones on the guanylate cyclase from guinea pig gastric mucosa.

1978 • 10 citations

Effect of Ca2+, Mg2+, NaN3, cholinergic agents, and gastrointestinal hormones on the guanylate cyclase from guinea pig gastric mucosa

1978 • 9 citations

Amino Acids and Ethanol

1979 • 9 citations

Influence of three inducers on rabbit gamma-glutamyltransferase

1980 • 8 citations

Hepatic Gamma-Glutamyl Transferase and Hepatic Fibrosis in Patients with Alcoholic Liver Disease

1984 • 7 citations

ETOH depresses rat liver γ-glutamyl transpeptidase

1978 • 6 citations

Chenodeoxycholate feeding increases the output of plasma-membrane marker enzymes into rat bile

1983 • 5 citations

Alkohol und Pankreas

2002 • 4 citations

[Gamma-glutamyl-transpeptidase activity in liver diseases].

1973 • 4 citations

Regulation of the metabolism of plasma membrane proteins in hepatocytes

1981 • 3 citations

Alkoholtoxische Veränderungen der Hämatopoiese: Eine prospektive Studie bei chronischen Alkoholikern

1981 • 2 citations

Anstieg der adulten und fetalen Form der Gamma-Glutamyl-Transferase (GGT)-Aktivität im Serum bei Patienten mit alkoholischen Leberschäden

1980 • 2 citations

Effects of alcohol on the isoenzymes of rat brain gamma-glutamyl transpeptidase.

1977 • 2 citations

Increased Ethanol Concentration in Drinking Rats Modulates Hypothalamic Self-stimulation Behavior

1982 • 2 citations

Deleted Work

1955 • 0 citations