Core glycosylation of cytochrome P-450(arom). Evidence for localization of N terminus of microsomal cytochrome P-450 in the lumen.

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

ASSEMBLY OF ASPARAGINE-LINKED OLIGOSACCHARIDES

1985 • 4,790 citations

A C-terminal signal prevents secretion of luminal ER proteins

1987 • 2,189 citations

Isolation of intracellular membranes by means of sodium carbonate treatment: application to endoplasmic reticulum.

1982 • 1,765 citations

The P450 Superfamily: Update on New Sequences, Gene Mapping, Accession Numbers, Early Trivial Names of Enzymes, and Nomenclature

1993 • 1,663 citations

Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum.

1990 • 918 citations

Control of Protein Exit from the Endoplasmic Reticulum

1989 • 794 citations

[6] Preparation of microsomal membranes for cotranslational protein translocation

1983 • 679 citations

Proposal for a common oligosaccharide intermediate in the synthesis of membrane glycoproteins

1977 • 489 citations

Determination of the distance between the oligosaccharyltransferase active site and the endoplasmic reticulum membrane.

1993 • 443 citations

On the membrane topology of vertebrate cytochrome P-450 proteins.

1988 • 362 citations

Isolation of a full-length cDNA insert encoding human aromatase system cytochrome P-450 and its expression in nonsteroidogenic cells.

1988 • 302 citations

[3] Cell-free translation of messenger RNA in a wheat germ system

1983 • 301 citations

Microsomal cytochrome P-450 from neonatal pig testis. Purification and properties of A C21 steroid side-chain cleavage system (17 alpha-hydroxylase-C17,20 lyase).

1981 • 298 citations

Attachment of terminal N-acetylglucosamine to asparagine-linked oligosaccharides occurs in central cisternae of the golgi stack

1985 • 291 citations

Synthesis of the membrane fusion and hemagglutinin proteins of measles virus, using a novel baculovirus vector containing the beta-galactosidase gene

1990 • 245 citations

Topography of glycosylation reactions in the endoplasmic reticulum

1992 • 237 citations

A short amino-terminal segment of microsomal cytochrome P-450 functions both as an insertion signal and as a stop-transfer sequence.

1987 • 215 citations

Functions of signal and signal-anchor sequences are determined by the balance between the hydrophobic segment and the N-terminal charge.

1992 • 180 citations

Cloning of a complete cDNA encoding human aromatase : Immunochemical identification and sequence analysis

1988 • 164 citations

Novel Properties of Human Placental Aromatase as Cytochrome P-450: Purification and Characterization of a Unique Form of Aromatase1

1988 • 155 citations

Signals for the incorporation and orientation of cytochrome P450 in the endoplasmic reticulum membrane.

1988 • 151 citations

Membrane topology of the mammalian P450 cytochromes

1992 • 139 citations

Positive charges at the NH2 terminus convert the membrane-anchor signal peptide of cytochrome P-450 to a secretory signal peptide.

1988 • 135 citations

Efficient site-directed in vitro mutagenesis using phagemid vectors.

1989 • 118 citations

Signal recognition particle is required for co-translational insertion of cytochrome P-450 into microsomal membranes.

1984 • 118 citations

Purification to homogeneity of aromatase from human placenta

1986 • 107 citations

Transfection with baculovirus DNA

1980 • 94 citations

Biochemical and molecular genetic analyses on placental aromatase (P-450AROM) deficiency.

1992 • 90 citations

The amino-terminal structures that determine topological orientation of cytochrome P-450 in microsomal membrane.

1990 • 90 citations

Purification and reconstitution properties of human placental aromatase. A cytochrome P-450-type monooxygenase

1986 • 65 citations

The endoplasmic reticulum retention signal of the E3/19K protein of adenovirus type 2 consists of three separate amino acid segments at the carboxy terminus.

1990 • 60 citations

An N-terminal glycosylation signal on cytochrome P450 is restricted to the endoplasmic reticulum in a luminal orientation.

1993 • 54 citations

Mitochondrial Porin Can Be Translocated across Both Endoplasmic Reticulum and Mitochondrial Membranes1

1992 • 50 citations

Estrogen synthetase (aromatase). The cytochrome P-450 component of the human placental enzyme is a glycoprotein

1991 • 35 citations

Is cytochrome P-450 transported from the endoplasmic reticulum to the Golgi apparatus in rat hepatocytes?

1985 • 33 citations

Purification and organ-specific properties of cholecalciferol 25-hydroxylase system: Cytochrome P-450D25-linked mixed function oxidase system

1980 • 28 citations

Localization of the N-terminal methionine of rat liver cytochrome P-450 in the lumen of the endoplasmic reticulum

1991 • 25 citations