Hypotensive Peptides: Bradykinin, Kallidin, and Eledoisin

The Pharmacological Basis of Therapeutics

1976 • 8,675 citations

Methods of enzymatic analysis

1964 • 5,230 citations

Thomas, Springfield, Illinois

1965 • 2,935 citations

BRADYKININ, A HYPOTENSIVE AND SMOOTH MUSCLE STIMULATING FACTOR RELEASED FROM PLASMA GLOBULIN BY SNAKE VENOMS AND BY TRYPSIN

1949 • 815 citations

The pharmacological basis of therapeutics

1955 • 718 citations

Vascular reactions to histamine, histamine‐liberator and leukotaxine in the skin of guinea‐pigs

1952 • 535 citations

A FAMILIAL HEMORRHAGIC TRAIT ASSOCIATED WITH A DEFICIENCY OF A CLOT-PROMOTING FRACTION OF PLASMA 1

1955 • 454 citations

The action of peptides on the adrenal medulla. Release of adrenaline by bradykinin and angiotensin

1964 • 361 citations

THE SPECIFIC ESTERASE ACTIVITY OF TRYPSIN

1948 • 334 citations

Bradykinin formation in human skin as a factor in heat vasodilatation

1958 • 311 citations

An enzyme in human blood plasma that inactivates bradykinin and kallidins

1962 • 307 citations

Pain‐producing substance in human inflammatory exudates and plasma

1957 • 303 citations

RELEASE OF A KININ PEPTIDE IN THE CARCINOID SYNDROME

1964 • 297 citations

Advances in Biology of Skin

1961 • 280 citations

A MICROMETHOD FOR DETERMINATION OF BRADYKININOGEN UNDER SEVERAL CONDITIONS*

1963 • 279 citations

Hereditary angioneurotic edema

1962 • 276 citations

Observations on chemical excitants of cutaneous pain in man

1953 • 264 citations

Polypeptides Which Affect Smooth Muscles and Blood Vessels

1961 • 259 citations

Actions of pure bradykinin

1960 • 252 citations

Structure and pharmacological actions of eledoisin, the active endecapeptide of the posterior salivary glands of eledone

1962 • 226 citations

The relationship between glandular activity, bradykinin formation and functional vaso‐dilatation in the submandibular salivary gland

1956 • 204 citations

PROCEEDINGS OF THE PHYSIOLOGICAL SOCIETY

1955 • 202 citations

THE NATURE OF THE KALLIDINS RELEASED FROM HUMAN PLASMA BY KALLIKREINS AND OTHER ENZYMES

1963 • 198 citations

Action of Complement in Hereditary Angioneurotic Edema: The Role of C′1-Esterase *

1964 • 193 citations

Synthèse de la <scp>L</scp>‐arginyl‐<scp>L</scp>‐prolyl‐<scp>L</scp>‐prolyl‐glycyl‐<scp>L</scp>‐phénylalanyl‐<scp>L</scp>‐Séryl‐<scp>L</scp>‐prolyl‐<scp>L</scp>‐phénylalanyl‐<scp>L</scp>‐arginine, un nonapeptide présentant les propriétés de la bradykinine

1960 • 189 citations

The action of angiotensin and bradykinin on the superior cervical ganglion of the cat.

1965 • 189 citations

Bradykinin as a vasodilator in man

1961 • 182 citations

Active Polypeptides Derived From Plasma Proteins

1960 • 173 citations

Ein neues Kreislaufhormon und seine Wirkung

1928 • 163 citations

FORMATION OF BRADYKININ IN ANAPHYLACTIC AND PEPTONE SHOCK

1950 • 153 citations

The structure of bradykinin — A plasma kinin from ox blood

1960 • 148 citations

THE INTERRELATIONSHIP OF COAGULATION OF PLASMA AND RELEASE OF PEPTIDES

1963 • 145 citations

Human plasma kallidins: Isolation and chemical studies

1961 • 142 citations

Influence of kallidin-10 on renal function

1964 • 141 citations

EFFECT OF LARGE DOSES OF AUREOMYCIN ON HUMAN LIVER

1951 • 139 citations

Polypeptides which Stimulate Plain Muscle

1955 • 138 citations

ENZYMATIC STUDIES ON BRADYKININ AND SIMILAR PEPTIDES

1963 • 138 citations

SOME PROTEOLYTIC ACTIVITIES OF SNAKE VENOMS

1955 • 138 citations

Der Nachweis eines Kreislaufhormons in der Pankreasdrüse. (IV. Mitteilung über dieses Kreislaufhormon.)

1930 • 134 citations

Substances which affect capillary permeability.

1958 • 130 citations

Formation of plasma kinins by plasmin

1958 • 129 citations

Structure and pharmacological actions of physalaemin, the main active polypeptide of the skin ofPhysalaemus fuscumaculatus

1964 • 128 citations

Polypeptides which Affect Smooth Muscles and Blood Vessels

1961 • 127 citations

Kinin‐forming activity and histamine in lymph after tissue injury

1963 • 123 citations

The modern treatment of shock based on physiologic principles

1964 • 123 citations

Spektrophotometrische Bestimmung des Kallikreins und seiner Inaktivatoren

1961 • 123 citations

The mediation of increased vascular permeability in inflammation.

1962 • 122 citations

Relationships between the chemical structures and the biological properties of the posterior pituitary hormones and their synthetic analogues

1961 • 121 citations

The Kinetics of Carboxypeptidase B Activity

1962 • 118 citations

Biochemical Mechanisms in Inflammation

1960 • 115 citations

The release of vasoactive substances in acute pancreatitis

1963 • 111 citations

Carboxypeptidase in blood and other fluids—I.

1964 • 106 citations

Bradykinin, Digital Blood Flow, and the Arteriovenous Anastomoses

1962 • 103 citations

CHEMICAL MEDIATORS OF THE ACUTE INFLAMMATORY REACTION*

1964 • 102 citations

Serotonin — bradykinin potentiation on the pain receptors in man

1965 • 102 citations

Action of the Kallikreins on Synthetic Ester Substrates

1961 • 102 citations

Vasodilatation in the submaxillary gland of the cat.

1965 • 101 citations

EFFECT OF BRADYKININ ON RENAL FUNCTION.

1965 • 100 citations

The isolation of bradykinin, a plasma kinin from ox blood

1961 • 99 citations

Shock Pathogenesis and Therapy

1962 • 97 citations

Development of Pain-producing Substance in Human Plasma

1954 • 96 citations

The demonstration of the role of mediators in turpentine pleurisy in rats by experimental suppression of the inflammatory changes

1959 • 96 citations

THE PHYSIOLOGICAL SIGNIFICANCE OF BRADYKININ*

1963 • 94 citations

Role of Hageman Factor in the Activation of Vasodilator Activity in Human Plasma

1961 • 94 citations

Neurohumoral Features of Afferent Fibers in Man

1961 • 93 citations

The effect of bradykinin, serum kallikrein and other endogenous substances on capillary permeability in the guinea‐pig

1960 • 86 citations

Mechanism of action of angiotensin and bradykinin on smooth muscle in situ

1961 • 85 citations

Isolierung und Struktur des Kallidins

1961 • 85 citations

Release of pharmacologically active substances from the rat skin in vivo following thermal injury.

1961 • 84 citations

Potentiation of bradykinin by dimercaptopropanol (BAL) and other inhibtors of its destroying enzyme in plasma

1962 • 83 citations

Occurrence of bradykinin in the skin of Rana temperaria

1965 • 78 citations

General Circulatory Alterations Induced by Intravenous Infusion of Synthetic Bradykinin in Man

1964 • 78 citations

The isolation and amino acid sequence of eledoisin, the active endecapeptide of the posterior salivary glands of Eledone

1963 • 77 citations

Identification of acetylcholine, 5‐hydroxytryptamine, histamine, and a new kinin in hornet venom (V. crabro)

1961 • 77 citations

PHARMACOLOGICAL ACTIONS OF BRADYKININ AND ITS ROLE IN PHYSIOLOGICAL AND PATHOLOGICAL REACTIONS

1963 • 76 citations

Bradykinin and cardiovascular system: estimation of half-life

1962 • 75 citations

Kinin formation by plasmin, an indirect process mediated by activation of kallikrein

1964 • 75 citations

PATHOGENESIS OF INFLAMMATION

1965 • 74 citations

THE EVALUATION OF INCREASED VASCULAR PERMEABILITY IN THE SKIN OF GUINEA‐PIGS

1964 • 74 citations

Über ein neues Kreislaufhormon. II. Mitteilung.

1928 • 74 citations

Isolation and amino acid sequence of physalaemin, the main active polypeptide of the skin of Physalaemus fuscumaculatus

1964 • 73 citations

POLYPEPTIDES WHICH STIMULATE PLAIN MUSCLE

1957 • 72 citations

Über einen von der Niere ausgeschiedenen, die Herztätigkeit anregenden Stoff.

1926 • 71 citations

The estimation of urinary kallikrein

1959 • 70 citations

AN IN VIVO ESTIMATION OF THE POTENCIES AND HALF-LIVES OF SYNTHETIC BRADYKININ AND KALLIDIN.

1965 • 69 citations

LARGE MOLECULAR SUBSTANCES AS MEDIATORS OF THE INFLAMMATORY REACTION

1964 • 69 citations

Studies on Snake Venoms*

1965 • 68 citations

Methionyl-lysyl-bradykinin, a new kinin from ox blood

1965 • 68 citations

Synthetic peptides related to eledoisin

1964 • 67 citations

The Role of Pancreatic Enzymes in the Pathogenesis of Acute Pancreatitis

1962 • 67 citations

The Biochemical Response to Injury

1960 • 64 citations

Proteolytic Activity in Development of Pain and Itching

1960 • 64 citations

Plasma‐kinin‐forming enzymes in body fluids and tissues

1959 • 64 citations

A NEW PANCREATIC CARBOXYPEPTIDASE

1956 • 64 citations

Effects of Bradykinin on the Systemic and Coronary Vascular Bed of the Intact Dog

1962 • 63 citations

Bradykinin Writhing: A Method for Measuring Analgesia.

1963 • 63 citations

Studies in Headache

1957 • 62 citations

THE PARTICIPATION OF THE NERVOUS SYSTEM IN THE INFLAMMATORY REACTION

1964 • 61 citations

Inhibition in vivo of the enzymatic inactivation of bradykinin and kallidin

1963 • 61 citations

DISTRIBUTION AND METABOLIC FATE OF ANGIOTENSIN II AND VARIOUS DERIVATIVES.

1964 • 60 citations

Synthesis of eledoisin

1962 • 59 citations

CENTRAL EFFECTS OF PEPTIDES ON THE CARDIOVASCULAR SYSTEM*

1963 • 59 citations

Studies on the physiological activity of the peptide released during the fibrinogen-fibrin conversion

1964 • 59 citations

Trypsin Release, Kinin Production, and Shock

1964 • 58 citations

�ber Zusammenh�nge zwischen esterolytischen und pharmakologischen Wirkungen von Jararacagift, Kallikrein und Thrombin

1959 • 58 citations

Über eine neue innersekretorische Funktion des Pankreas

1930 • 58 citations

Carboxypeptidase in blood and other fluids. Values in human blood in normal and pathological conditions

1965 • 58 citations

THE ACTION AND ANTAGONISM OF KININS ON BRONCHIOLES

1963 • 57 citations

Susceptibility of the Guinea Pig to Pharmacological Factors from its Own Serum

1953 • 57 citations

The effect of vascular permeability factors on the emigration of leucocytes

1964 • 56 citations

Zur Kenntnis der blutdrucksenkenden Wirkung des Trypsins

1955 • 56 citations

ACTIVATION OF HAGEMAN FACTOR BY SATURATED FATTY ACIDS

1962 • 56 citations

Studies on plasma kallikrein and its relationship to plasmin.

1960 • 56 citations

Coronary Vasodilation Produced by Bradykinin on Isolated Mammalian Heart

1962 • 55 citations

Kinin‐forming and destroying activities of cell homogenates.

1965 • 55 citations

PURIFICATION AND SOME PROPERTIES OF THREE RALLIKREINS

1963 • 55 citations

Bradykinin, kallidin, and their synthetic analogues

1964 • 54 citations

NATURE OF PEPTIDES RELEASED BY THROMBIN

1963 • 54 citations

Purification of bradykinin by ion-exchange chromatography

1956 • 53 citations

Release of kinin by an enzyme in the accessory sex glands of the guinea‐pig

1962 • 53 citations

The permeability to plasma proteins of the peritoneal blood vessels of the mouse, and the effect of substances that alter permeability

1963 • 53 citations

Solid Phase Peptide Synthesis. IV. The Synthesis of Methionyl-lysyl-bradykinin¹

1964 • 52 citations

�ber Substrate und Reaktionsprodukte der kininbildenden Enzyme Trypsin, Serum- und Pankreaskallikrein sowie von Crotalusgift

1964 • 52 citations

Pancreatitis—Intrapancreatic Proteolytic Trypsin Activity

1963 • 51 citations

Hemodynamic effects of angiotensin, norepinephrine, and bradykinin continuously measured in unanesthetized dogs

1961 • 51 citations

Effect of Inhibitors of Fibrinolytic Enzymes on Development of Pulmonary Metastases2

1964 • 51 citations

KALLIKREIN, KALLIDIN, KALLIKREIN INHIBITORS

1963 • 50 citations

HAGEMAN FACTOR AND CAPILLARY PERMEABILITY

1959 • 50 citations

Potentiation of duration of the vasodilator effect of bradykinin by sympatholytic drugs and by reserpine.

1960 • 49 citations

The effect of bradykinin in an isolated perfused dog lung preparation

1961 • 49 citations

Enhancement of fibrinolysis in the dog by injection of vasoactive drugs

1965 • 49 citations

Hemmung von Proteinasen durch Kallikrein-Inaktivatoren

1952 • 49 citations

Significance of the callicrein-callidinogen-callidin system in shock

1959 • 48 citations

The role of trypsin in the pathogenesis of acute hemorrhagic pancreatitis and the effect of an antitryptic agent in treatment.

1952 • 48 citations

Über den Nachweis und das Vorkommen des Kallikreins im Blut. VIII. Mitteilung über Kallikrein.

1933 • 47 citations

Occurrence of an eledoisin-like polypeptide (physalaemin) in skin extracts ofPhysalaemus fuscumaculatus

1962 • 47 citations

Release of a kinin by intraperitoneal injection of chemical agents in mice

1964 • 47 citations

Augmentation of the Inflammatory Reaction by Activity of the Central Nervous System

1959 • 46 citations

THE PERMEABILITY GLOBULINS OF HUMAN SERUM AND THE BIOCHEMICAL MECHANISM OF HEREDITARY ANGIONEUROTIC EDEMA

1964 • 46 citations

MICROCIRCULATORY ASPECTS OF TISSUE INJURY*

1964 • 45 citations

Glycine Analogs of Bradykinin

1963 • 45 citations

Studies on Polypeptides. XXIV. Synthesis and Biological Evaluation of a Tricosapeptide Possessing Essentially the Full Biological Activity of ACTH^1-4

1962 • 45 citations

BLOCKING OF THE IN VIVO EFFECTS OF BRADYKININ AND KALLIDIN WITH CARBOXYPEPTIDASE B.

1963 • 44 citations

Experimental Pancreatitis

1963 • 44 citations

General and Regional Circulatory Effects of Synthetic Bradykinin in Man

1964 • 44 citations

Bradykinin

1961 • 44 citations

�ber Kreislaufwirkungen von synthetischem Bradykinin beim Menschen und beim wachen Hund

1961 • 44 citations

Role of Bradykinin in the Development of Acute Pancreatitis

1964 • 43 citations

A comparative pharmacological study of synthetic eledoisin and synthetic bradykinin.

1963 • 43 citations

Proceedings of the Biochemical Society

1960 • 43 citations

Inhibition of the Local Hemorrhagic Shwartzman Reaction by a Polypeptide Possessing Potent Antiprotease Activity

1964 • 43 citations

STUDIES ON THE CARDIOVASCULAR EFFECTS OF SYNTHETIC OXYTOCIN.

1963 • 43 citations

ON THE RELATIONSHIP BETWEEN PLASMIN AND KININ*

1963 • 42 citations

Bradykinin and forearm blood flow

1964 • 42 citations

The estimation of the kallidins in blood and urine

1965 • 41 citations

Rapid Induction by Acetylcholine, Bradykinin and Potassium of a Nociceptive Response in Mice and its Selective Antagonism by Aspirin

1964 • 41 citations

Über Peptidsynthesen. C-terminale Teilsequenzen des Eledoisins und eledoisinanaloger Verbindungen

1964 • 41 citations

STUDIES ON PLASMA KININS

1963 • 41 citations

Kinin formation and fibrinolysis in human plasma

1963 • 40 citations

Kallidin, Synthese und Eigenschaften. (Vorläufige Mitteilung)

1962 • 39 citations

Strukturuntersuchungen am Kallikrein -Inaktivator aus Rinderlunge

1965 • 39 citations

THE SYNTHESIS OF KININ ANALOGUES

1963 • 38 citations

Zum Problem eines Antidotes in der internen Thrombotherapie mit Fibrinolytika

1959 • 38 citations

Trennung und Reinigung von Pankreaskallikreinen

1962 • 38 citations

THE PRESENCE OF TWO PERMEABILITY GLOBULINS IN HUMAN SERUM*

1963 • 37 citations

The synthesis of a biologically active decapeptide having the structure proposed for kallidin II

1961 • 37 citations

Ricerche preliminari sulla moschatina

1949 • 37 citations

Über esteratische Wirkungen von Kallikrein und Trypsin und ihre Hemmung durch Kallikrein- und Trypsininhibitoren

1960 • 37 citations

Kinins--A Group of Active Peptides

1964 • 37 citations

Partielle Reinigung und einige Eigenschaften eines Kininogens aus Rinderblut

1963 • 37 citations

Isolierung von Bradykinin aus Rinderplasma nach Einwirkung von Schlangengift (Bothrops jararaca). Vorläufige Mitteilung

1960 • 37 citations

Activation of bovine bradykininogen by human plasmin

1965 • 36 citations

Anti-Heparin Agents as Inhibitors of Plasma Kinin Formation

1962 • 36 citations

Partial purification of the plasma substrate for the bradykinin-releasing enzyme from the venom of Bothrops jararaca

1962 • 36 citations

A pharmacological comparison between synthetic bradykinin and synthetic kallidin.

1963 • 36 citations

Studies on the isolation of Bradykininogen

1963 • 36 citations

Stimulation médullo-surrénalienne par la bradykinine

1961 • 35 citations

Bradykinin: Synthetic Bradykinin : its Biological Identity with Natural Pure Trypsin Bradykinin

1960 • 35 citations

Weal and Flare in Human Skin Produced by Histamine and other Substances

1959 • 35 citations

Strukturuntersuchungen am Kallikrein-Inaktivator aus Rinderlunge

1965 • 34 citations

Effect of the Endecapeptide Eledoisin on the Coronary Blood Flow: Comparison with Nitroglycerin, Bradykinin and Epinephrine in the Dog

1963 • 34 citations

Cardiac Action of Vasoactive Polypeptides in the Rat

1965 • 34 citations

Der Kallikreingehalt des Harns, des Speichels und des Blutes bei Gesunden und Kranken

1938 • 34 citations

Some observations on salivary secretion

1935 • 34 citations

Neuere Ergebnisse auf dem Gebiet der Plasmakinine

1963 • 33 citations

[A new hypotensive, enterotropic and hysterotropic substance in human urine].

1954 • 33 citations

Biological Effects of External Radiation

1954 • 32 citations

The endecapeptide eledoisin as powerful vasodilating and hypotensive agent in man

1963 • 32 citations

RELEASE OF ANTIDIURETIC HORMONE BY BRADYKININ.

1964 • 32 citations

The action of vasopressin, a vasopressin analogue (PLV₂), oxytocin, angiotensin, bradykinin and theophylline ethylene diamine on renal blood flow in the anaesthetized cat

1963 • 32 citations

Synthesis and Biological Properties of L-Arginyl-L-Prolyl-L-Prolyl-Glycyl-L-Phenylalanyl-L-Seryl-L-Phenylalanyl-L-Arginine, an Octapeptide related to Bradykinin

1960 • 32 citations

The antagonism of substances that increase vascular permeability in the rat

1963 • 32 citations

Adrenaline precursors in the inflammatory reaction

1964 • 31 citations

Enzymic Nature of the Serum Globulin Permeability Factor

1959 • 31 citations

Potentiation of bradykinin action on smooth-muscle by cysteine

1962 • 31 citations

Synthèse de la <scp>L</scp>‐arginyl‐<scp>L</scp>‐prolyl‐<scp>L</scp>‐prolyl‐glycyl‐<scp>L</scp>‐phénylalanyl‐<scp>L</scp>‐Séryl‐<scp>L</scp>‐phénylalanyl‐<scp>L</scp>‐arginine. Distinction entre cet octapeptide et la bradykinine

1960 • 31 citations

Über Peptidsynthesen. Synthese von Methionyl-Lysyl-Bradykinin, einem Kinin aus Rinderblut

1964 • 31 citations

The Protective Effect of Proteinase Inhibitor in Acute Necrotizing Pancreatitis

1963 • 30 citations

Citrulline-Containing Analogs of Bradykinin

1963 • 30 citations

Bradykinin-releasing Factor from Bothrops jararaca venom

1960 • 30 citations

Synthese von <scp>L</scp>‐Arginyl‐<scp>L</scp>‐propyl‐<scp>L</scp>‐propyl‐glycyl‐<scp>L</scp>‐phenylalanyl‐<scp>L</scp>‐seryl‐<scp>L</scp>‐phenylalanyl‐<scp>L</scp>‐arginin (Bradykinin?). Vorläufige Mitteilung

1960 • 30 citations

Hemodynamic effects of eledoisin, kallidin II, and bradykinin in unanesthetized dogs

1962 • 29 citations

Interrelationship of Human Plasma Kallikrein and Plasmin in Inflammation

1965 • 29 citations

BRADYKININ AND ITS MODE OF RELEASE

1963 • 29 citations

Specificity of mammalian kallidinogen

1964 • 29 citations

A comparative study of the effects of bradykinin, kallidin II and eledoisin on segmental superior mesenteric resistance

1965 • 29 citations

d-Aminosäurehaltige Analoga des Eledoisins

1965 • 29 citations

�ber eine esterspaltende Wirkung von Kallikrein

1959 • 28 citations

Hypertensive Effects of Bradykinin in Rats

1961 • 28 citations

Synthetic peptides related to eledoisin

1964 • 28 citations

Fortschritte auf dem Gebiet der Plasmakinine

1962 • 28 citations

USE OF CRYSTALLINE SOYBEAN TRYPSIN INHIBITOR IN ACUTE HEMORRHAGIC PANCREATITIS IN DOGS

1953 • 27 citations

Pharmacologically-active polypeptide formed from blood globulin by a cysteine-activated protease from Clostridium histolyticum

1956 • 27 citations

The systemic and coronary hemodynamic effects of synthetic bradykinin

1963 • 27 citations

THE EFFECT OF BRADYKININ ON VASCULAR SMOOTH MUSCLE*

1963 • 27 citations

The activation by irritants of slowcontracting substances, and their relation to the vascular changes of inflammation in the rat

1962 • 27 citations

Purification of Bovine Bradykininogen*

1965 • 27 citations

Interrelations Between Different Mechanisms of Release of Biologically Active Peptides from Blood Plasma

1962 • 27 citations

KININS OF DIFFERENT ORIGINS

1963 • 27 citations

Über die Stimulierung der Atmung durch Bradykinin und Kallidin

1964 • 27 citations

Beiträge zur Pharmakologie des Trypsins

1939 • 26 citations

Retrobradykinin: a Peptide with the Reverse Sequence of Bradykinin

1962 • 26 citations

�ber eine neue blutdrucksenkende, darm-und uteruserregende Substanz im menschlichen Urin

1954 • 26 citations

Cerebral vascular action of bradykinin in the dog

1961 • 26 citations

Synthetic peptides related to eledoisin (Part I)

1963 • 26 citations

Studies of the peptic degradation of bovine bradykininogen

1965 • 25 citations

Synthese des Bradykininanalogen mit umgekehrter Aminosäuresequenz

1962 • 25 citations

SYNTHETIC PEPTIDES RELATED TO BRADYKININ

1963 • 25 citations

Isolation and amino acid composition of bradykinin released by venom of Bothrops Jararaca from bovine plasma

1961 • 25 citations

THE DUAL MODE OF THE ANTISPASMODIC EFFECT OF DICYCLOMINE HYDROCHLORIDE.

1964 • 25 citations

�ber das Verhalten von Pankreasenzymen bei der experimentellen Pankreatitis der Ratte

1963 • 24 citations

Immunological properties of the kallikreins

1963 • 24 citations

Zur Frage des Entstehungsmechanismus des Kreislaufkollapses bei der akuten Pankreasnekrose

1955 • 24 citations

The Effect of a Trypsin Inhibitor, Trasylol, on the Course of Bile and Trypsin-Induced Pancreatitis in Dogs

1965 • 23 citations

THE ENZYMIC INACTIVATION OF SOME PHYSIOLOGICALLY ACTIVE POLYPEPTIDES BY DIFFERENT PARTS OF THE NERVOUS SYSTEM

1963 • 23 citations

Proteolytische Enzyme im Pankreas unter normalen und pathologischen Bedingungen

1964 • 23 citations

EFFECT OF DRUG INFUSION ON THE SYSTEMIC AND SPLANCHNIC CIRCULATION. I. BRADYKININ INFUSION IN NORMAL SUBJECTS.

1964 • 23 citations

Evidence for the renal origin of urinary kinin

1964 • 23 citations

Spontaneous Plasma Kinin Formation in Human Plasma collected during Labour

1960 • 23 citations

Substance U—a Depressor and Smooth-Muscle Stimulating Principle Present in Urine

1952 • 22 citations

Zuordnung pharmakologischer und enzymatischer Wirkungen von Kallikrein und Schlangengiften mittels Diisopropylfluorophosphat und Elektrophorese

1961 • 22 citations

Versuche zur Isolierung des Kallikrein-Inaktivators, III. Elektrophoretische Reinigung und Molekulargewichtsbestimmung in der Ultrazentrifuge

1960 • 22 citations

Über den Einfluss der Kettenlänge auf die biologische Aktivität eledoisinanaloger Verbindungen

1965 • 22 citations

Versuche zur Isolierung des Kallikrein-Inaktivators, V. Isolierung eines Kallikrein-Inaktivators aus Rinderlunge und seine Identifizierung mit dem Inaktivator aus Rinderparotis

1964 • 22 citations

Diisopropylfluorophosphat-Hemmung esterolytischer und pharmakologischer Wirkungen von Kallikrein und Schlangengiften

1960 • 22 citations

�ber das bradykininbildende Prinzip des Bothrops-Giftes

1959 • 21 citations

The Synthesis of 8-D-Phenylalanine-, 8-p-Fluoro-L-phenylalanine-, and 8-p-Fluoro-D-phenylalanine-bradykinin

1963 • 21 citations

SNAKE VENOMS, KALLIKREINS, AND KININOGEN*

1963 • 21 citations

Inhibitors of the in vivo enzymatic inactivation of bradykinin and kallidin

1963 • 21 citations

The Role of Mediators in the Inflammatory Tissue Response

1956 • 21 citations

Bradykinin Release and Inactivation in Man

1963 • 21 citations

Leistungen und Ergebnisse der neuzeitlichen Chirurgie

1958 • 21 citations

Peripheral Vasodilator Action of Eledoisin, Bradykinin, and Nitroglycerin in Anesthetized Dogs

1964 • 20 citations

THE ROLE OF BRADYKININ IN THE PERIPHERAL NERVOUS SYSTEM

1963 • 20 citations

Anaphylactic Shock in Dogs

1963 • 20 citations

Die Wirkungen von Bradykinin und Kallidin auf die Nierenfunktion des Hundes

1964 • 20 citations

Identifizierung eines „spontan“ aus Serumglobulin entstehenden Peptids mit Bradykinin

1961 • 20 citations

Apamin: ein basisches, zentral erregendes Polypeptid aus Bienengift

1964 • 19 citations

Der Einflu� von Bradykinin und Kallidin auf den Druck in der Arteria pulmonalis

1965 • 19 citations

Salicylate and Increased Vascular Permeability

1962 • 19 citations

Effect of Bradykinin on Isolated Coronary Arteries

1962 • 19 citations

A large scale preparation of bradykinin

1958 • 19 citations

Catheptic degradation of Bradykinin

1965 • 19 citations

Über ein neues inneres Sekret des Pankreas, das Kreislaufhormon Kallikrein, und seine therapeutische Verwendung

1931 • 18 citations

Acute Experimental Pancreatitis

1965 • 18 citations

Über die Wirkung einer reinen Gefäßerweiterung auf den Gesamtkreislauf

1931 • 18 citations

Studies on the Enzymatic Inactivation of Bradykinin.

1954 • 18 citations

Untersuchungen �ber die Wirksamkeit eines Trypsininhibitors (Trasylol�) auf Enzymaktivit�ten und Morphologie bei der Taurocholat- und Calciphylaxie-Pankreatitis der Ratte

1965 • 18 citations

Über einen Hemmkörper für Kallikrein und Trypsin in der Rinderlunge

1964 • 18 citations

Zur Kenntnis des Kallikreins. VII. Mitteilung.

1932 • 18 citations

Apnoe nach Bradykinin und Kallidin

1964 • 18 citations

General and regional circulatory effects of synthetic eledoisin in man

1964 • 18 citations

KININ‐FORMING ENZYME (KININOGENIN) IN RAT KIDNEY*

1964 • 18 citations

Experiments on the factor in urine forming substance U

1956 • 18 citations

Bradykinin-Induced Increase in Total and Effective Blood Flow in Skeletal Muscle

1962 • 18 citations

Synthèse d'analogues structuraux de l'élédoïsine (3ème partie)

1964 • 17 citations

The kinin content of human blood at rest and during vasodilatation

1965 • 17 citations

Nachweis und Vorkommen des Kallikreins im Harn. IX. Mitteilung über Kallikrein.

1934 • 17 citations

Kininases in Leucocytes and other Tissues

1962 • 17 citations

The Synthesis of 6-O-Carbamyl-L-Serine, 6-D-Serine, and 6-L-Threonine Bradykinin

1963 • 17 citations

EFFECT OF A TRYPSIN-INHIBITOR ON EXPERIMENTALLY INDUCED PANCREATITIS IN THE DOG.

1963 • 17 citations

Effect of Bradykinin on Uterine Activity

1961 • 17 citations

THE BRADYKININOGEN CONTENT OF PLASMA FROM WOMEN IN LABOUR*

1962 • 17 citations

Das Verhalten des Kallikrein-Inaktivators aus Rinderparotis gegenüber Fermenten, II

1963 • 16 citations

Die Beeinflussung des Kreislaufes durch Organextrakte (sogenannte Kreislaufhormone)

1931 • 16 citations

Pharmacological characteristics of bradykinin B

1960 • 16 citations

Versuche zur Isolierung des Kallikrein-Inaktivators, IV. Kristallisation und Aminosäurezusammensetzung, Vergleich mit dem Trypsin-Inhibitor von Kunitz und Northrop

1963 • 16 citations

Wirkungsunterschied zwischen den Polypeptiden Bradykinin und Substanz P am Zentralnervensystem

1956 • 15 citations

Effect of Trypsin Inhibitors on Shwartzman Phenomenon.

1961 • 15 citations

Biochemical Mechanisms in Inflammation

1956 • 15 citations

Vascular Permeability Factors in the Secretion of the Guinea Pig Coagulating Gland

1958 • 15 citations

Über die Wirkung adenosinartiger Stoffe und einiger Organextrakte auf die Kapillaren

1933 • 15 citations

Unterscheidung von Kallikreinen und Kallikreinvorstufe mittels Antiseren und Diisopropylfluorophosphats

1962 • 14 citations

Significance of Histamine in Trypsin Shock as Determined by Benadryl.

1946 • 14 citations

POSSIBLE SIGNIFICANCE OF BRADYKININ IN THE SHWARTZMAN AND OTHER PHENOMENA*

1963 • 14 citations

Kallikrein and Histamine

1940 • 14 citations

Activity of eledoisin, other polypeptides and ergometrine on the uterus in situ of rabbit and other animal species

1964 • 14 citations

Synthese von Lys^1.9‐Bradykinin und Lys^2.10‐Kallidin

1964 • 14 citations

Bronchoconstrictor Action of Bradykinin, Kallidin and Eledoisin

1965 • 14 citations

Renotrope Wirkungen von synthetischem Bradykinin

1963 • 14 citations

The importance of bradykinin in anaphylactic shock

1965 • 14 citations

Étude comparée des effets de la bradykinine et des réactions anaphylactiques locales chez l’homme

1962 • 13 citations

Bronchoconstrictor Action of Bradykinin, Kallidin and Eledoisin

1965 • 13 citations

Metal ion complexing properties of carcinogen metabolites

1963 • 13 citations

The Origin of Bradykinin

1952 • 13 citations

Use of Heparin in Distinguishing Plasma Kallikrein from Pf/dil

1965 • 13 citations

Presence of carboxypeptidase B in crude kallikrein (padutin) preparations

1962 • 13 citations

Quantitative Relation Between Certain Fibrinolysis Factors and Inflammation

1963 • 13 citations

TISSUE INJURY BY TRYPSIN

1942 • 13 citations

Kallikrein im Inneren und Äusseren Pankreassekret

1933 • 13 citations

Die Wirkung des Histamins, Serotonins, Bradykinins, Eledoisins und Hypertensins auf isoliert durchstr�mte Arterien-, Venen- und Bronchienpr�parate der Meerschweinchenlunge

1964 • 13 citations

Depressor polypeptides

1960 • 13 citations

DIE WIRKUNG VON BRADYKININ‐AEROSOL AUF DIE ATMUNG DES MENSCHEN UND DES MEER‐SCHWEINCHENS UND DER EINFLUSS VER‐SCHIEDENER SUBSTANZEN AUF DEN EXPERI‐MENTELLEN BRADYKININ‐BRONCHOSPASMUS

1963 • 13 citations

Neural Activity and Polypeptides

1959 • 13 citations

Über die Wirkung von Proteinaseinhibitor-Präparaten (Leberund Parotisinhibitor) auf die extravasale Fibrinolyse, Fibrinogenolyse und Blutgerinnungskonstanten im Menschenblut

1963 • 13 citations

Über einen Hemmkörper für Kallikrein und verschiedene Proteinasen aus Rinderleber II

1959 • 12 citations

Zur Kenntnis der blutdrucksenkenden und spasmolytischen Wirkung des Kallikreins und der Substanz DK

1943 • 12 citations

Synthese und biologische Aktivität bradykininwirksamer Undeca-, Dodeca- und Tridecapeptide

1965 • 12 citations

Untersuchungen �ber die Kreislaufwirkung von Eledoisin am Menschen und im Tierversuch

1963 • 12 citations

On some antagonists of bradykinin

1965 • 12 citations

BRADYKININE ET CHOC ANAPHYLACTIQUE DU LAPIN

1959 • 12 citations

�ber die Aktivierung proteolytischer Proenzyme des Pankreas

1965 • 12 citations

Über die Wirkung intravenöser Kallikreinzufuhr auf den tierischen Organismus

1932 • 12 citations

Kininase Inhibition by a Fluorescent Substance Prepared from Liver

1964 • 11 citations

Wirkung von Thioglykolsäure auf Kininogen und Kininase

1964 • 11 citations

A Study of the Cutaneous Effects of Bradykinin**From the Division of Dermatology, Faculty of Medicine, University of British Columbia, Vancouver, B.C.

1964 • 11 citations

A comparison of the plasma kinin forming enzymes in urine; kallikrein and urokinase

1959 • 11 citations

[On the antifibrinolytic effect of trypsin--kallikrein inactivator].

1961 • 11 citations

THE PHARMACOLOGIC PROPERTIES OF AN INSULIN-FREE EXTRACT OF PANCREAS AND THE CIRCULATORY HORMONE OF FREY

1931 • 11 citations

BIOGENIC AMINES AND ACTIVE POLYPEPTIDES IN THE SKIN OF TEN JAPANESE AMPHIBIAN SPECIES

1964 • 11 citations

PURIFICATION OF THE DEPRESSOR COLLOID OF URINE (CALLICREIN)

1935 • 11 citations

Zur Wirkung von Bradykinin und Kallidin auf den Druck in der Arteria pulmonalis

1963 • 11 citations

A DISCUSSION OF THE EVIDENCE FOR KININS AS THE AGENTS OF VASODILATOR REACTIONS*

1963 • 11 citations

A spreading factor from serum

1939 • 10 citations

Activation of Endogenous Plasma Proteolytic Enzymes with the Consequent Production of Pharmacologically Active Polypeptides

1962 • 10 citations

Antihistamine and Antibradykinin Effects of Normal Urine Extracts

1963 • 10 citations

Vergleichende Untersuchungen �ber die Kreislaufwirkung von Kallikrein (Padutin), Kallidin und Bradykinin

1962 • 10 citations

The secretagogue and depressor substances in saliva and pancreatic juice

1936 • 10 citations

Über die Wirkung intravenöser und intramuskulärer Kallikreininjektionen beim Menschen

1935 • 10 citations

Excretion of Human Urinary Kinins

1965 • 10 citations

Isolation and molar activity of human bradykinin

1962 • 10 citations

STUDIES ON PLASMA KININS

1963 • 9 citations

Zur Frage der Identit�t von Kallidinogen und Bradykininogen

1956 • 9 citations

Vasopressor responses to kallidin, bradykinin and eledoisin in hypotensive rats

1964 • 9 citations

Antagonistic Action of Urokinase to Brady-kinin- and Plasminogen-induced Capillary Permeability

1963 • 9 citations

The enzymatic formation of the vasopressor polypeptide substance a by a crystalline enzyme of Bacillus subtilus

1964 • 9 citations

Zur Kenntnis der Pankreassaftwirkung bei parenteraler Einführung

1925 • 9 citations

THE EFFECTS OF ELEDOISIN AND SUBSTANCE P IN THE DOG CROSS CIRCULATION PREPARATION.

1965 • 9 citations

Sur le rôle du complément dans le choc anaphylactique du lapin

1964 • 8 citations

Calf blood flow and oxygen usage during bradykinin infusions

1963 • 8 citations

Bradykinin: Configurations of the Arginine Moieties and Biological Activity^*

1965 • 8 citations

Pressor effect of synthetic eledoisin in chickens

1964 • 8 citations

Homologous serum proteins and their role in phenomena of increased capillary permeability in inflammation

1956 • 8 citations

Bradykinin und Eledoisin, vergleichende pharmakologische Untersuchungen

1963 • 8 citations

Kreislaufuntersuchungen �ber Eledoisin mit Therapieresultaten

1965 • 8 citations

Charakterisierung des pharmakodynamischen Wirkungsspektrums blutdrucksenkender Stoffe

1957 • 8 citations

Die Wirkung intravenöser Kallikreingaben auf den Liquordruck

1935 • 8 citations

Zur Frage der bronchoconstrictorischen Wirkung des Bradykinins, Kallidins und Eledoisins

1963 • 8 citations

Malignolipin and Malignant Tumours

1962 • 8 citations

Excretion of Urinary Kinin in Man

1964 • 7 citations

Die Wirkung von TEAB auf die Bradykininkontraktion des isolierten Rattenuterus

1959 • 7 citations

Inhibitory action of fibrinolysin and other proteolytic enzymes on capillary permeability induced by histamine, serotonin and bradykinin

1962 • 7 citations

�ber die Wirkung von synthetischem Eledoisin auf die Nierenfunktion, den Wasser- und Elektrolythaushalt beim Menschen

1964 • 7 citations

Über das Padutin

1934 • 7 citations

Versuche zur Isolierung eines niedermolekularen Kininogens

1963 • 7 citations

Purification of a Secondary Kinin from Human Urine; A Pharmacological and Chromatographic Comparison with Kallidin

1964 • 7 citations

Bradykinin Antagonism Following Oral Protease Therapy

1963 • 7 citations

Die körpereigenen uteruswirksamen und kreislaufaktiven Wirkstoffe im Schwangerenorganismus

1941 • 6 citations

Permeability Response of Cerebral and Cutaneous Blood Vessels to Vasoactive Agents

1962 • 6 citations

Antagonisme entre salicylate de soude et bradykinine chez le rat

1962 • 6 citations

Effects on Smooth Muscle and Blood Vessels of Polypeptides Related to Bradykinin and to Kallidin

1963 • 6 citations

Zum Mechanismus der Kininfreilegung aus der gereinigten Vorstufe und kininliefernden Teilsequenzen

1964 • 6 citations

Effect of pH and Chloride Ions on Plasma Kininase Activity

1963 • 6 citations

Biological Effects of External Radiation

1955 • 6 citations

[On the treatment of severe burns by Trasylol, an enzyme inactivator].

1962 • 6 citations

�ber die kombinierte Wirkung von Kallikrein und Nor-Adrenalin auf die Muskel- und Hautdurchblutung des Menschen

1959 • 5 citations

A Clinical and Experimental Study of the Action of Tissue Extracts on the Circulatory System

1934 • 5 citations

Effect of Eledoisin on the Systemic Venous Return in Dogs.

1965 • 5 citations

Chemical Studies on Callicrein. VI

1959 • 5 citations

The Euglobulin Method for Estimation of Fibrinolytic Activity in Urokinase-Activated Plasma, and the Influence of Trasylol

1964 • 5 citations

The Euglobulin Method for Estimation of Fibrinolytic Activity in Urokinase-Activated Plasma, and the Influence of Trasylol

1964 • 4 citations

[METABOLIC DISORDERS IN INOPERABLE CANCER AND THEIR TREATMENT BY INHIBITORS].

1964 • 3 citations

[STUDY OF SOME PHARMACOLOGICAL EFFECTS ON SYSTEMIC AND SPLANCHNIC HEMODYNAMICS. I. ACTION OF BRADYKININ ON NORMAL HUMANS].

1963 • 3 citations

Beeinflussung isolierter Mitochondrien durch einige Polypeptide und biogene Amine

1965 • 3 citations

Versuche zur Isolierung des Kallikreins, III. Darstellung einer Kallikrein-Zink-Verbindung

1958 • 3 citations

Kreislaufuntersuchungen mit Eledoisin am Menschen

1964 • 3 citations

Tritium-Markierung und Organverteilung eines basischen Polypeptids mit leukotaktischer und permeationsf�rdernder Wirkung

1964 • 3 citations

Hemodynamic Effects of Eledoisin in Man

1964 • 3 citations

PRELIMINARY REPORT ON TREATMENT AND PROPHYLAXIS OF ACUTE PANCREATITIS WITH A KALLIKREIN-TRYPSIN INHIBITOR.

1964 • 3 citations

[Modification of urinary kallikrein excretion in man and rats by various diets].

1962 • 2 citations

[Regulation of urinary kallikrein excretion by the pituitary and adrenal glands].

1962 • 2 citations