Mammalian cloning: advances and limitations

Embryonic Stem Cell Lines Derived from Human Blastocysts

1998 • 15,541 citations

Viable offspring derived from fetal and adult mammalian cells

1997 • 4,774 citations

Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei

1998 • 2,257 citations

Sheep cloned by nuclear transfer from a cultured cell line

1996 • 1,823 citations

Completion of mouse embryogenesis requires both the maternal and paternal genomes

1984 • 1,529 citations

Derivation of pluripotent stem cells from cultured human primordial germ cells

1998 • 1,415 citations

Cloned Transgenic Calves Produced from Nonquiescent Fetal Fibroblasts

1998 • 1,408 citations

Cloned pigs produced by nuclear transfer from adult somatic cells

2000 • 1,243 citations

Eight Calves Cloned from Somatic Cells of a Single Adult

1998 • 1,062 citations

Human Factor IX Transgenic Sheep Produced by Transfer of Nuclei from Transfected Fetal Fibroblasts

1997 • 906 citations

Pig Cloning by Microinjection of Fetal Fibroblast Nuclei

2000 • 842 citations

Nuclear transplantation in sheep embryos

1986 • 813 citations

Role of paternal and maternal genomes in mouse development

1984 • 704 citations

Production of gene-targeted sheep by nuclear transfer from cultured somatic cells

2000 • 624 citations

Nuclear Transplantation in the Mouse Embryo by Microsurgery and Cell Fusion

1983 • 581 citations

The Sins of the Fathers and Mothers

1999 • 489 citations

Six cloned calves produced from adult fibroblast cells after long-term culture

2000 • 488 citations

Mice cloned from embryonic stem cells

1999 • 482 citations

Cloning of male mice from adult tail-tip cells

1999 • 474 citations

Extension of Cell Life-Span and Telomere Length in Animals Cloned from Senescent Somatic Cells

2000 • 471 citations

Nuclear Transplantation in the Bovine Embryo: Assessment of Donor Nuclei and Recipient Oocyt14

1987 • 390 citations

Isolation of pluripotent embryonic stem cells from reprogrammed adult mouse somatic cell nuclei

2000 • 359 citations

Imprinting and the Initiation of Gene Silencing in the Germ Line

1998 • 359 citations

Generation of mice from wild-type and targeted ES cells by nuclear cloning

2000 • 348 citations

Inability of Mouse Blastomere Nuclei Transferred to Enucleated Zygotes to Support Development in Vitro

1984 • 348 citations

Nuclear transplantation in mus musculus: Developmental potential of nuclei from preimplantation embryos

1981 • 268 citations

Lymphoid hypoplasia and somatic cloning

1999 • 258 citations

Production of Male Cloned Mice from Fresh, Cultured, and Cryopreserved Immature Sertoli Cells1

2000 • 243 citations

Cloning of mice to six generations

2000 • 228 citations

Mitochondrial DNA genotypes in nuclear transfer-derived cloned sheep

1999 • 221 citations

Active Remodeling of Somatic Nuclei in Egg Cytoplasm by the Nucleosomal ATPase ISWI

2000 • 219 citations

Nuclear-Cytoplasmic Interactions during the First Cell Cycle of Nuclear Transfer Reconstructed Bovine Embryos: Implications for Deoxyribonucleic Acid Replication and Development1

1993 • 213 citations

Production of calves by transfer of nuclei from cultured inner cell mass cells.

1994 • 205 citations

Birth of Mice after Transplantation of Early Cell-Cycle-Stage Embryonic Nuclei into Enucleated Oocytes1

1993 • 184 citations

Mitochondrial DNA heteroplasmy in cloned cattle produced by fetal and adult cell cloning

2000 • 174 citations

Mechanisms and Control of Embryonic Genome Activation in Mammalian Embryos

1999 • 173 citations

Down-regulation of the Inositol 1,4,5-Trisphosphate Receptor in Mouse Eggs Following Fertilization or Parthenogenetic Activation

2000 • 173 citations

NO is necessary and sufficient for egg activation at fertilization

2000 • 172 citations

Spatiotemporal Analysis of Ca2+ Waves in Relation to the Sperm Entry Site and Animal–Vegetal Axis during Ca2+ Oscillations in Fertilized Mouse Eggs

2000 • 171 citations

Postnatal Growth and Behavioral Development of Mice Cloned from Adult Cumulus Cells1

2000 • 159 citations

Nuclear transfer into mouse zygotes

2000 • 150 citations

Full‐term development of mouse blastomere nuclei transplanted into enucleated two‐cell embryos

1987 • 148 citations

Influence of Cell Cycle Stage of the Donor Nucleus on Development of Nuclear Transplant Rabbit Embryos1

1992 • 146 citations

Nuclear cytoplasmic interactions following nuclear transplantation in mouse embryos

1987 • 135 citations

Birth of mice after nuclear transfer by electrofusion using tail tip cells

2000 • 133 citations

Putting Stem Cells to Work

1999 • 130 citations

Inositol 1,4,5-Trisphosphate Receptors Are Downregulated in Mouse Oocytes in Response to Sperm or Adenophostin A but Not to Increases in Intracellular Ca2+ or Egg Activation

2000 • 124 citations

Production of identical sextuplet mice by transferring metaphase nuclei from four-cell embryos

1996 • 119 citations

Nuclear transplantation in the rabbit egg

1975 • 109 citations

Clone: The Road to Dolly, and the Path Ahead

1997 • 109 citations

Nuclear transplantation by microinjection of inner cell mass and granulosa cell nuclei

1994 • 107 citations

Nuclear Transplantation in Mouse Embryos: Assessment of Recipient Cell Stage1

1986 • 98 citations

Review: Somatic Cell Nuclear Transfer in Mammals: Progress and Applications

1999 • 93 citations

Genomic Potential of Differentiated Cells

1997 • 92 citations

Transfer of embryonic nuclei to fertilised mouse eggs and development of tetraploid blastocysts

1978 • 84 citations

Cloning: Pathways to a Pluripotent Future

2000 • 81 citations

Heterospecific genome interaction

1970 • 67 citations

Influence of cell cycle stage at nuclear transplantation on the development in vitro of mouse embryos

1988 • 64 citations

Not only inner cell mass cell nuclei but also trophectoderm nuclei of mouse blastocysts have a developmental totipotency

1998 • 61 citations

The fate of inner cell mass and trophectoderm nuclei transplanted to fertilized mouse eggs

1981 • 55 citations

A Simplified Method for the Reconstruction of Fully Competent Mouse Zygotes from Adult Somatic Donor Nuclei

2000 • 50 citations

[35] Construction of primary and subtracted cDNA libraries from early embryos

1993 • 47 citations

Transfer of nuclei from 8‐cell stage mouse embryos following use of nocodazole to control the cell cycle

1994 • 45 citations

Relationship between nuclear remodeling and subsequent development of mouse embryonic nuclei transferred to enucleated oocytes

1994 • 43 citations

5 Nuclear Transplantation in Mammalian Eggs and Embryos

1995 • 32 citations

Production of identical twin and triplet mice by nuclear transplantation

1991 • 30 citations

In His Image: The Cloning of a Man

1978 • 29 citations

The Second Creation

2000 • 28 citations

The Regulation and Reprogramming of Gene Expression in the Preimplantation Embryo

1999 • 8 citations

Cloning's owners go to war

2000 • 5 citations

Cell fusion in the study of tumor cells.

1971 • 4 citations