Improved buccal delivery of opioid analgesics and antagonists with bitterless prodrugs.

Rationale for Design of Biologically Reversible Drug Derivatives: Prodrugs

1975 • 223 citations

Sublingual buprenorphine used postoperatively: ten hour plasma drug concentration analysis.

1982 • 169 citations

Sublingual buprenorphine used postoperatively: clinical observations and preliminary pharmacokinetic analysis.

1981 • 115 citations

The systemic bioavailability of buprenorphine by various routes of administration

1981 • 96 citations

BUCCAL MORPHINE—A NEW ROUTE FOR ANALGESIA?

1985 • 82 citations

Improvement of the Oral Bioavailability of Naltrexone in Dogs: A Prodrug Approach

1987 • 55 citations

Buccal and oral bioavailability of naloxone and naltrexone in rats

1987 • 42 citations

Chemical Modification of Clindamycin: Synthesis and Evaluation of Selected Esters

1973 • 29 citations

Prodrugs for improved oral nalbuphine bioavailability: inter-species differences in the disposition of nalbuphine and its acetylsalicylate and anthranilate esters

1987 • 28 citations

Buccal and Oral Bioavailability of Nalbuphine in Rats

1986 • 25 citations

Buccal morphine premedication

1986 • 21 citations

Oral and rectal nalbuphine bioavailability: First‐pass metabolism in rats and dogs

1985 • 16 citations

Physical Model Approach to Taste Studies of Drugs and Pharmaceutical Formulations

1984 • 2 citations