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Chimeric Analogues of Vertebrate Gonadotropin-Releasing Hormones Comprising Substitutions of the Variant Amino Acids in Positions 5, 7, and 8

Data up to Jan 2025

Published1989
Citations91
References33

Total Citations Per Year

Abstract

References (33)

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

Gonadotropin-Releasing Hormone Analog Design. Structure-Function Studies Toward the Development of Agonists and Antagonists: Rationale and Perspective

1986 • 559 citations

A RADIOIMMUNOASSAY FOR AVIAN LUTEINIZING HORMONE

1972 • 520 citations

Identification of the second gonadotropin-releasing hormone in chicken hypothalamus: evidence that gonadotropin secretion is probably controlled by two distinct gonadotropin-releasing hormones in avian species.

1984 • 455 citations

Characterization of a teleost gonadotropin-releasing hormone.

1983 • 340 citations

Primary structure of gonadotropin-releasing hormone from lamprey brain.

1986 • 252 citations

Structure of chicken hypothalamic luteinizing hormone-releasing hormone. II. Isolation and characterization.

1982 • 226 citations

Structure of chicken hypothalamic luteinizing hormone-releasing hormone. I. Structural determination on partially purified material.

1982 • 220 citations

Heterogeneity of Vertebrate Luteinizing Hormone-Releasing Hormone

1979 • 116 citations

Further Studies on the Radioimmunoassay of Gonadotropin-Releasing Hormone: Effect of Radioiodination, Antiserum and Unextracted Serum on Levels of Immunoreactivity in Serum1

1977 • 111 citations

Structure-activity relationships of mammalian, chicken, and salmon gonadotropin releasing hormones in vivo in goldfish

1985 • 101 citations

Receptor Binding and Gonadotropin-Releasing Activity of a Novel Chicken Gonadotropin-Releasing Hormone ([His5, Trp7, Tyr8]GnRH) and a D-Arg6Analog*

1986 • 98 citations

Binding Affinity and Biological Activity of Gonadotropin-Releasing Hormone Agonists in Isolated Pituitary Cells

1982 • 94 citations

Evidence that chicken hypothalamic luteinizing hormone- releasing hormone is [Gln8]-LHRH

1983 • 94 citations

Luteinizing Hormone-Releasing Hormone: Sequential Versus Conformational Specificity of Antiluteinizing Hormone-Releasing Hormone Sera*

1979 • 90 citations

PHARMACOLOGY OF HYPOTHALAMIC REGULATORY PEPTIDES

1976 • 72 citations

Metabolic Clearance and Plasma Half-Disappearance Time of D-TRP6and Exogenous Luteinizing Hormone-Releasing Hormone*

1982 • 70 citations

Degradation of luteinizing hormone — Releasing hormone and analogs by adenohypophyseal peptidases

1981 • 65 citations

Synthesis, Luteinizing Hormone-Releasing Activity, and Receptor Binding of Chicken Hypothalamic Luteinizing Hormone-Releasing Hormone*

1983 • 65 citations

Structure‐Activity relations of LHRH in birds

1984 • 56 citations

Gonadotropin-Releasing Hormone Receptors in Human Pituitary: Ligand Structural Requirements, Molecular Size, and Cationic Effects*

1985 • 55 citations

Structural and Functional Evolution of Gonadotropin-Releasing Hormone

1987 • 54 citations

Molecular Dynamics and Minimum Energy Conformations of GnRH and Analogs: A Methodology for Computer‐aided Drug Designa

1985 • 51 citations

Structural features of luliberin (luteinising hormone-releasing factor) inferred from fluorescence measurements

1976 • 40 citations

Comparative Biological Properties of Lamprey Gonadotropin-Releasing Hormone in Vertebrates*

1987 • 40 citations

GnRH-Receptor of rat pituitary is a glycoprotein: Differential effect of neuraminidase and lectins on agonists and antagonists binding

1982 • 39 citations

Application of Ovine Luteinizing Hormone (LH) Radioimmunoassay in the Quantitation of LH in Different Mammalian Species

1977 • 38 citations

Biological Properties of Chicken Luteinizing Hormone-Releasing Hormone: Gonadotropin Release from Rat and Chicken Cultured Anterior Pituitary Cells and Radioligand Analysis

1984 • 37 citations

Comparative structure-activity studies on mammalian [Arg8] LH-RH and chicken [Gln8] LH-RH by fluorimetric titration

1983 • 37 citations

IMMUNOCHEMICAL AND CHROMATOGRAPHIC SIMILARITY OF RAT, RABBIT, CHICKEN AND SYNTHETIC LUTEINIZING HORMONE RELEASING HORMONES

1974 • 31 citations

Evidence for an FSH-releasing factor in the posterior portion of the rat median eminence

1983 • 30 citations

Synthesis and biological activity of [D-Trp6] chicken luteinizing hormone-releasing hormone

1983 • 16 citations

Decapeptides as effective agonists from L-amino acids biologically equivalent to the luteinizing hormone-releasing hormone.

1986 • 16 citations

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