Posttranscriptional Regulation of IL-10 Gene Expression Through Sequences in the 3′-Untranslated Region

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.

1991 • 3,812 citations

A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

1997 • 3,625 citations

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.

1989 • 2,771 citations

AU-rich elements: characterization and importance in mRNA degradation

1995 • 1,936 citations

Interleukin-10

1993 • 1,820 citations

Homology of Cytokine Synthesis Inhibitory Factor (IL-10) to the Epstein-Barr Virus Gene BCRFI

1990 • 1,155 citations

Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production.

1993 • 945 citations

Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI.

1991 • 752 citations

Ly‐1 B (B‐1) cells are the main source of B cell‐derived interleukin 10

1992 • 525 citations

Identification and induction of keratinocyte-derived IL-10.

1992 • 342 citations

AUUUA Is Not Sufficient To Promote Poly(A) Shortening and Degradation of an mRNA: the Functional Sequence within AU-Rich Elements May Be UUAUUUA(U/A)(U/A)

1994 • 331 citations

Identification of HuR as a protein implicated in AUUUA-mediated mRNA decay

1997 • 302 citations

IL-10 Gene Expression Is Controlled by the Transcription Factors Sp1 and Sp3

2000 • 258 citations

Identification of TIAR as a Protein Binding to the Translational Regulatory AU-rich Element of Tumor Necrosis Factor α mRNA

1999 • 256 citations

Interleukin‐10 production by human carcinoma cell lines and its relationship to interleukin‐6 expression

1993 • 245 citations

TCR-dependent and -independent signaling mechanisms differentially regulate lymphokine gene expression in the murine T helper clone D10.G4.1.

1994 • 54 citations

Possible Involvement of Proteasomes (Prosomes) in AUUUA-mediated mRNA Decay

1999 • 53 citations

Structure of Abnormal Heavy Chains in Human Heavy-chain-deposition Disease

1995 • 53 citations

Mapping of a Minimal AU-rich Sequence Required for Lipopolysaccharide-induced Binding of a 55-kDa Protein on Tumor Necrosis Factor-α mRNA

1998 • 41 citations

NIPP-1, a Nuclear Inhibitory Subunit of Protein Phosphatase-1, Has RNA-binding Properties

1997 • 40 citations

Structure of Abnormal Heavy Chains in Human Heavy-chain-deposition Disease

1995 • 39 citations

Binding of neuronal ELAV‐like proteins to the uridine‐rich sequence in the 3′‐untranslated region of tumor necrosis factor‐α messenger RNA

1999 • 37 citations

Species differences in the intestinal response to sulphate ions

1969 • 13 citations