Contribution of tyrosine 6 to the catalytic mechanism of isoenzyme 3-3 of glutathione S-transferase.

[6] Statistical analysis of enzyme kinetic data

1979 • 2,002 citations

Glutathione Transferases—Structure and Catalytic Activit

1988 • 1,751 citations

Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties.

1985 • 1,081 citations

Theta, a new class of glutathione transferases purified from rat and man

1991 • 743 citations

GLUTATHIONE S-TRANSFERASES: GENE STRUCTURE, REGULATION, AND BIOLOGICAL FUNCTION

1989 • 624 citations

The three-dimensional structure of class pi glutathione S-transferase in complex with glutathione sulfonate at 2.3 A resolution.

1991 • 356 citations

Determining the Chemical Mechanisms of Enzyme‐Catalyzed Reactions by Kinetic Studies

1977 • 340 citations

Glutathione S-transferases: reaction mechanism, structure, and function

1991 • 334 citations

Glutathione S-transferases and drug resistance

1991 • 299 citations

Effect of manganese ions on the incorporation of dideoxynucleotides by bacteriophage T7 DNA polymerase and Escherichia coli DNA polymerase I.

1989 • 292 citations

Hydrogen bonds involving sulfur atoms in proteins

1991 • 240 citations

Spectroscopic and kinetic evidence for the thiolate anion of glutathione at the active site of glutathione S-transferase

1989 • 165 citations

Dissection of the catalytic mechanism of isozyme 4-4 of glutathione S-transferase with alternative substrates

1988 • 106 citations

Redox forms of human placenta glutathione transferase.

1991 • 88 citations

Ultraviolet spectroscopy of proteins

1987 • 82 citations

Formation of the 1-(S-glutathionyl)-2,4,6-trinitrocyclohexadienate anion at the active site of glutathione S-transferase: evidence for enzymic stabilization of .sigma.-complex intermediates in nucleophilic aromatic substitution reactions

1989 • 81 citations

Active site-directed irreversible inhibition of glutathione S-transferases by the glutathione conjugate of tetrachloro-1,4-benzoquinone.

1988 • 81 citations

Irreversible inhibition of rat glutathione S-transferase 1-1 by quinones and their glutathione conjugates. Structure-activity relationship and mechanism

1991 • 67 citations

Effects of directed mutagenesis on conserved arginine residues in a human Class Alpha glutathione transferase

1991 • 63 citations

A Steady‐State‐Kinetic Random Mechanism for Glutathione S‐Transferase A from Rat Liver

1977 • 63 citations

Localization of a portion of the active site of two rat liver glutathione S-transferases using a photoaffinity label

1989 • 51 citations

S-(4-Bromo-2,3-dioxobutyl)glutathione: a new affinity label for the 4-4 isoenzyme of rat liver glutathione S-transferase

1991 • 42 citations

Crystallization and a preliminary X-ray diffraction study of isozyme 3-3 of glutathione S-transferase from rat liver

1987 • 39 citations

Are the histidine residues of glutathione S-transferase important in catalysis? An assessment by 13C NMR spectroscopy and site-specific mutagenesis.

1991 • 31 citations

Construction, expression, and preliminary characterization of chimeric class μ glutathione S‐transferases with altered catalytic properties

1990 • 28 citations

Site-directed mutagenesis of glutathione S-transferase YaYa: Nonessential role of histidine in catalysis

1991 • 26 citations

Cysteine-86 is not needed for the enzymic activity of glutathione S-transferase 3-3

1991 • 22 citations