Prostaglandins, bioassay and inflammation

Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

1971 • 8,596 citations

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

1976 • 3,613 citations

Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.

1975 • 3,075 citations

An unidentified depressor substance in certain tissue extracts

1931 • 1,565 citations

Aspirin Selectively Inhibits Prostaglandin Production in Human Platelets

1971 • 1,535 citations

Prostaglandin Endoperoxides. Novel Transformations of Arachidonic Acid in Human Platelets

1974 • 1,410 citations

A NEW DEFICIENCY DISEASE PRODUCED BY THE RIGID EXCLUSION OF FAT FROM THE DIET

1929 • 1,140 citations

Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides

1976 • 1,012 citations

Isolation and Structure of Two Prostaglandin Endoperoxides That Cause Platelet Aggregation

1974 • 1,004 citations

ON THE NATURE AND RÔLE OF THE FATTY ACIDS ESSENTIAL IN NUTRITION

1930 • 961 citations

Indomethacin and Aspirin abolish Prostaglandin Release from the Spleen

1971 • 940 citations

Release of Additional Factors in Anaphylaxis and its Antagonism by Anti-inflammatory Drugs

1969 • 886 citations

Isolation and properties of intermediates in prostaglandin biosynthesis

1973 • 796 citations

The chemical structure of prostaglandin X (prostacyclin)

1976 • 729 citations

THE RELEASE OF PROSTAGLANDINS FROM LUNG AND OTHER TISSUES

1971 • 658 citations

Detection and Isolation of an Endoperoxide Intermediate in Prostaglandin Biosynthesis

1973 • 640 citations

Biosynthesis of Prostaglandins

1991 • 503 citations

Effects of Anti-inflammatory Drugs on Prostaglandin Biosynthesis

1972 • 478 citations

THE USE OF ISOLATED ORGANS FOR DETECTING ACTIVE SUBSTANCES IN THE CIRCULATING BLOOD

1964 • 478 citations

The enzymatic formation of prostaglandin E2 from arachidonic acid prostaglandins and related factors 32

1964 • 473 citations

On the specific vaso‐dilating and plain muscle stimulating substances from accessory genital glands in man and certain animals (prostaglandin and vesiglandin)

1936 • 452 citations

Zur Kenntnis der pharmakologischen Wirkungen von Nativsekreten und Extrakten männlicher accessorischer Geschlechtsdrüsen

1934 • 403 citations

Properties of human seminal plasma

1935 • 361 citations

The Isolation of Prostaglandin F from Sheep Prostate Glands.

1960 • 318 citations

Release of Noradrenaline from Sympathetic Endings

1971 • 316 citations

Physiological role of an endoperoxide in human platelets: hemostatic defect due to platelet cyclo-oxygenase deficiency.

1975 • 312 citations

Über die Spezifische Blutdrucksenkende Substanz des Menschlichen Prostata- und Samenblasensekretes

1935 • 305 citations

Biochemical Studies of Human Semen. II. The Action of Semen on the Human Uterus.

1930 • 282 citations

The Isolation of Prostaglandin E from Sheep Prostate Glands.

1960 • 246 citations

On the Incorporation of Oxygen in the Conversion of 8,11,14-Eicosatrienoic Acid to Prostaglandin E₁

1965 • 231 citations

Prostaglandin endoperoxides VII. Novel transformations of arachidonic acid in guinea pig lung

1974 • 226 citations

Biosynthesis of Prostaglandins from Arachidonic Acid in Guinea Pig Lung

1965 • 201 citations

Studies on prostaglandin; occurrence, formation and biological actions.

1959 • 179 citations

An endoperoxide aggregator (LASS), formed in platelets in response to thrombotic stimuli-purification, identification and unique biological significance

1974 • 178 citations

The Isolation of Prostaglandin.

1957 • 167 citations

Novel prostaglandin derivative formed from arachidonic acid by rat stomach homogenates

1971 • 163 citations

A NEW DEFICIENCY DISEASE PRODUCED BY THE RIGID EXCLUSION OF FAT FROM THE DIET

2009 • 155 citations

ANALGESIC ANTIPYRETIC DRUGS AS ANTAGONISTS OF BRADYKININ

1960 • 137 citations

EFFECT OF ASPIRIN ON HUMAN SEMINAL PROSTAGLANDINS

1971 • 113 citations

Weitere Untersuchungen über Prostaglandin, die physiologisch aktive Substanz gewisser Genitaldrüsen¹

1939 • 96 citations

Prostaglandins and the Aspirin-Like Drugs

1972 • 81 citations

The generation from arachidonic acid of rabbit aorta contracting substance (RCS) by a microsomal enzyme preparation which also generates prostaglandins

1972 • 66 citations

THE USE OF ISOLATED ORGANS FOR DETECTING ACTIVE SUBSTANCES IN THE CIRCULATING BLOOD

1997 • 60 citations

Über das Vorkommen des Prostaglandins in Tierorganen¹

1937 • 37 citations

Prostaglandins from bedside observation to a family of drugs

1981 • 17 citations

Transformation of prostaglandin G2 into 6(9)-oxy-11,15-dihydroxy-prosta-7,13-dienoic acid by the rat stomach fundus

1976 • 16 citations

[Further studies of prostaglandin, the physically active substance of certain genital glands].

1939 • 14 citations

Mediators of the anaphylactic reaction.

1971 • 9 citations

Prostaglandin, historical remarks

1981 • 6 citations

Synthesis and exchange of phospholipids within brain and liver cells.

1972 • 6 citations

Mediators of the anaphylactic reaction.

1971 • 5 citations

Deleted Work

1955 • 0 citations