Role of Polyclonal Activation in Specific Immune Responses.

Towards a network theory of the immune system.

1974 • 3,379 citations

Autoimmune Response to Acetylcholine Receptor

1973 • 1,019 citations

Serum Globulin in Myasthenia Gravis: Inhibition of α-Bungarotoxin Binding to Acetylcholine Receptors

1974 • 365 citations

Immune Activation of B Cells: Evidence for‘One Nonspecific Triggering Signal' Not Delivered by the Ig Receptors

1974 • 244 citations

In vitro effects of Epstein-Barr virus on peripheral blood mononuclear cells from patients with rheumatoid arthritis and normal subjects.

1978 • 244 citations

MECHANISM OF THYMUS-INDEPENDENT IMMUNOCYTE TRIGGERING

1974 • 230 citations

A New Approach to the Study of Human B Lymphocyte Function Using an Indirect Plaque Assay and a Direct B Cell Activator

1979 • 181 citations

Most IgM-producing cells in the mouse secrete auto-antibodies (rheumatoid factor)

1978 • 175 citations

IgM Rheumatoid Factors in Mice Injected with Bacterial Lipopolysaccharides

1979 • 161 citations

Lymphokines in the rheumatoid joint

1975 • 140 citations

Characterization of self-reactive B cells by polyclonal B-cell activators.

1977 • 125 citations

Induction of DNA synthesis in human lymphocytes: interaction between non-specific mitogens and antigens.

1970 • 107 citations

Evidence of Similar Idiotypic Determinants on Different Rheumatoid Factor Populations

1979 • 98 citations

Immunological Characterization of Lymphocytes in Synovial Fluid from Patients with Rheumatoid Arthritis

1973 • 78 citations

The Polyclonal B‐Cell‐Activating Property of Protein A Is Not Due to Its Interaction with the Fc Part of Immunoglobulin Receptors

1977 • 66 citations

In Vitro Mitogen Stimulation of Synovial Fluid Lymphocytes from Rheumatoid Arthritis and Juvenile Rheumatoid Arthritis Patients: Dissociation between the Response to Antigens and Polyclonal Mitogens

1978 • 65 citations

Induction of Monoclonal Antibody Synthesis in Malignant Human B Cells by Polyclonal B Cell Activators

1979 • 61 citations

Certain Rheumatoid Factors React with both IgG and an Antigen Associated with Cell Nuclei

1978 • 54 citations

Induction of Antibody Synthesis in Human B Lymphocytes by Different Polyclonal B Cell Activators: Evaluation by Direct and Indirect PFC Assays

1979 • 47 citations

Non‐HLA Lymphocyte Cytotoxins in Various Diseases

1979 • 41 citations

Monoclonal and polyclonal gamma M rheumatoid factors with anti-di- and anti-trinitrophenyl activity.

1969 • 39 citations

Shared antigenic determinants by mitogen receptors and antibody molecules to the same thymus-independent antigen.

1978 • 35 citations

ANTITHYROID-ANTIBODY ACTIVITY IN THE SYNOVIAL FLUID OF PATIENTS WITH VARIOUS ARTHRITIDES

1979 • 33 citations

IgM‐Rheumatoid Factors Cross‐reactive with IgG and a Cell Nuclear Antigen: Apparent ‘Masking’ in Original Serum

1979 • 33 citations

The response of synovial fluid lymphocytes to T and B stimulants in vitro.

1973 • 33 citations

Tuberculous Meningitis: Immune Reactions within the Central Nervous System

1981 • 27 citations

Demonstration of Rheumatoid Factor Idiotypic Antigens on Peripheral Blood B and T Lymphocytes from Patients with Rheumatoid Arthritis

1979 • 24 citations

Con‐A‐activated T Cells Secrete Factors with Polyclonal B‐Cell‐activating Properties

1979 • 19 citations

Demonstration of Anti‐Rubella Antibody‐secreting Cells in Rheumatoid Arthritis Patients

1979 • 18 citations

Immunological unresponsiveness of self-recognizing B lymphocytes to the PBA property of a soluble T cell factor

1978 • 10 citations