Microsomal enzymes of cholesterol biosynthesis. Purification of lanosterol 14 alpha-methyl demethylase cytochrome P-450 from hepatic microsomes.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The colorimetric estimation of formaldehyde by means of the Hantzsch reaction

1953 • 4,357 citations

Some properties of a detergent-solubilized NADPH-cytochrome c(cytochrome P-450) reductase purified by biospecific affinity chromatography.

1976 • 1,180 citations

Oxygen Activation by Cytochrome P-4501

1980 • 1,013 citations

Evidence for Biochemically Different Types of Vesicles in the Hepatic Microsomal Fraction*

1966 • 754 citations

A Form of Cytochrome b ₅ That Contains an Additional Hydrophobic Sequence of 40 Amino Acid Residues

1971 • 453 citations

Characterization of three highly purified cytochromes P-450 from hepatic microsomes of adult male rats.

1984 • 301 citations

[22] The measurement of difference spectra: Application to the cytochromes of microsomes

1978 • 294 citations

Mechanistic studies on C-19 demethylation in oestrogen biosynthesis

1982 • 285 citations

7α-Hydroxylation of cholestanol by rat liver microsomes

1968 • 242 citations

Sex difference of cytochrome P-450 in the rat: Purification, characterization, and quantitation of constitutive forms of cytochrome P-450 from liver microsomes of male and female rats

1983 • 233 citations

Yeast cytochrome P-450 catalyzing lanosterol 14 alpha-demethylation. II. Lanosterol metabolism by purified P-450(14)DM and by intact microsomes.

1984 • 207 citations

Mechanism of induction of cytochrome P-450 by phenobarbital.

1981 • 159 citations

Sterol Biosynthesis

1982 • 143 citations

Yeast cytochrome P-450 catalyzing lanosterol 14 alpha-demethylation. I. Purification and spectral properties.

1984 • 127 citations

The Enzymes of Biological Membranes

1985 • 122 citations

Cytochrome P-450-dependent oxidation of lanosterol in cholesterol biosynthesis. Microsomal electron transport and C-32 demethylation.

1984 • 95 citations

NH2-terminal sequence analyses of four rat hepatic microsomal cytochromes P-4501

1984 • 88 citations

Multiplicity of Liver Drug Metabolizing Enzymes

1979 • 72 citations

Investigation of the Component Reactions of Oxidative Sterol Demethylation. Study of the Aerobic and Anaerobic Processes^*

1967 • 62 citations

Studies on the mechanism of lanosterol 14 α-demethylation. A requirement for two distinct types of mixed-function-oxidase systems

1979 • 61 citations

Oxidative demethylation of lanosterol in cholesterol biosynthesis: accumulation of sterol intermediates.

1986 • 49 citations

Evidence for the presence of cytochrome P-450 functional in lanosterol 14α-demethylation in microsomes of aerobically grown respiring yeast

1981 • 38 citations

Hydroxylations in biosynthesis of bile acids. Isolation of subfractions with different substrate specificity from cytochrome P-450LM4.

1982 • 37 citations

Proximity of the substrate binding site and the heme-iron catalytic site in cytochrome P-450scc.

1982 • 35 citations

Enzyme-bound sterols of bovine adrenocortical cytochrome P-450scc

1981 • 32 citations

Mechanism of cholesterol side‐chain cleavage: Enzymic rearrangement of 20β‐hydroperoxy‐20‐isocholesterol to 20β,21‐dihydroxy‐20‐isocholesterol

1976 • 31 citations

Competitive inhibition of cytochrome P-450scc by (22R)- and (22S)-22-aminocholesterol. Side-chain stereochemical requirements for C-22 amine coordination to the active-site heme.

1985 • 25 citations

Stimulatory Effect of Cytochrome b5 Induced by p-Nitroanisole and Diisopropyl 1,3-dithiol-2-ylidenemalonate on Rat Liver Microsomal Drug Hydroxylations1

1982 • 25 citations

Biosynthesis of Isoprenoids

1984 • 8 citations