Conformational changes of adenylate cyclase regulatory proteins mediated by guanine nucleotides.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

1977 • 5,640 citations

Mechanism of cholera toxin action: Covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system

1978 • 902 citations

The Glucagon-sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver

1971 • 811 citations

ADP-ribosylation of membrane proteins catalyzed by cholera toxin: basis of the activation of adenylate cyclase.

1978 • 732 citations

Mechanism of adenylate cyclase activation by cholera toxin: Inhibition of GTP hydrolysis at the regulatory site

1977 • 726 citations

Catecholamine-stimulated GTPase activity in turkey erythrocyte membranes

1976 • 623 citations

Relationship between the beta-adrenergic receptor and adenylate cyclase.

1977 • 497 citations

Reconstitution of hormone-sensitive adenylate cyclase activity with resolved components of the enzyme.

1978 • 480 citations

GTP-binding proteins in membranes and the control of adenylate cyclase activity.

1977 • 456 citations

Guanosine 5'-O-(2-thiodiphosphate). An inhibitor of adenylate cyclase stimulation by guanine nucleotides and fluoride ions.

1979 • 382 citations

Mechanism of adenylate cyclase activation through the beta-adrenergic receptor: catecholamine-induced displacement of bound GDP by GTP.

1978 • 372 citations

Activation of pigeon erythrocyte membrane adenylate cyclase by guanylnucleotide analogues and separation of a nucleotide binding protein.

1975 • 337 citations

Genetic evidence that cholera toxin substrates are regulatory components of adenylate cyclase.

1978 • 281 citations

Evidence for Interdependent Action of Glucagon and Nucleotides on the Hepatic Adenylate Cyclase System

1974 • 244 citations

Agonist-promoted coupling of the beta-adrenergic receptor with the guanine nucleotide regulatory protein of the adenylate cyclase system.

1980 • 229 citations

Reconstitution of catecholamine-sensitive adenylate cyclase activity: interactions of solubilized components with receptor-replete membranes.

1977 • 175 citations

Guanine nucleotide‐controlled interactions between components of adenylate cyclase

1979 • 144 citations

The role of the guanine nucleotide exchange reaction in the regulation of the beta-adrenergic receptor and in the actions of catecholamines and cholera toxin on adenylate cyclase in turkey erythrocyte membranes.

1980 • 126 citations

Adenylate cyclase assembled in vitro: cholera toxin substrates determine different patterns of regulation by isoproterenol and guanosine 5'-triphosphate.

1979 • 114 citations

A regulatory component of adenylate cyclase from human erythrocyte membranes.

1980 • 109 citations

Activation of Turkey erythrocyte adenylate cyclase and blocking of the catecholamine-stimulated GTPase by guanosine 5′-(γ-thio) triphosphate

1977 • 106 citations

Reconstitution of cholera toxin-activated adenylate cyclase.

1978 • 98 citations

Determination of the turn-off reaction for the hormone-activated adenylate cyclase.

1979 • 98 citations

Hydrodynamic properties of the regulatory component of adenylate cyclase.

1980 • 81 citations

Influence of cholera toxin on the regulation of adenylate cyclase by GTP

1977 • 71 citations

Peptide mapping of adenylate cyclase regulatory proteins that are cholera toxin substrates.

1980 • 47 citations