The effects of fatty acids on phosphoinositide synthesis and myo-inositol accumulation in exocrine pancreas.

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides

1983 • 1,937 citations

The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain.

1980 • 1,099 citations

The stimulation of inositol lipid metabolism that accompanies calcium mobilization in stimulated cells: defined characteristics and unanswered questions

1981 • 518 citations

Selective release of archidonic acid from the phospholipids of human platelets in response to thrombin.

1977 • 409 citations

Intracellular Ca2+ mobilization by arachidonic acid. Comparison with myo-inositol 1,4,5-trisphosphate in isolated pancreatic islets.

1986 • 310 citations

Phosphoinositides and Protein Secretion in Pancreas Slices

1958 • 248 citations

Activation of phospholipases A and C in human platelets exposed to epinephrine: role of glycoproteins IIb/IIIa and dual role of epinephrine.

1986 • 229 citations

Mechanism of action of gonadotropin-releasing hormone. Involvement of phospholipid turnover in luteinizing hormone release.

1981 • 208 citations

Arachidonic acid stimulates the formation of 1,2-diacylglycerol and phosphatidic acid in human platelets. Degree of phospholipase C activation correlates with protein phosphorylation, platelet shape change, serotonin release, and aggregation.

1983 • 205 citations

Receptor-mediated net breakdown of phosphatidylinositol 4,5-bisphosphate in parotid acinar cells

1982 • 182 citations

Inhibition of phosphatidylinositol synthesis and the inactivation of calcium entry after prolonged exposure of the blowfly salivary gland to 5-hydroxytryptamine

1979 • 181 citations

Purification of phosphatidylinositol-specific phospholipase C from rat liver.

1981 • 180 citations

Hormone selective lipase activation in the isolated rabbit heart

1977 • 142 citations

Effects of secretagogues on [32P]phosphatidylinositol 4,5-bisphosphate metabolism in the exocrine pancreas

1983 • 128 citations

Characterization of the secretory activity of leukotriene B4 toward rabbit neutrophils.

1982 • 122 citations

Triene prostaglandins: Prostaglandin D ₃ and icosapentaenoic acid as potential antithrombotic substances

1979 • 122 citations

Lithium-induced reduction in intracellular inositol supply in cholinergically stimulated parotid gland

1986 • 121 citations

The interaction of lithium with thyrotropin-releasing hormone-stimulated lipid metabolism in GH3 pituitary tumour cells. Enhancement of stimulated 1,2-diacylglycerol formation

1984 • 116 citations

Fatty acid stimulation of membrane phosphatidylinositol hydrolysis by brain phosphatidylinositol phosphodiesterase

1979 • 110 citations

Characterization of a calcium-mediated activation of arachidonic acid turnover in adrenal phospholipids by corticotropin.

1979 • 106 citations

Effect of long chain unsaturated fatty acids on the calcium transport of sarcoplasmic reticulum

1981 • 99 citations

Secretogogue-stimulated phosphatidylinositol breakdown in the exocrine pancreas liberates arachidonic acid, stearic acid, and glycerol by sequential actions of phospholipase C and diglyceride lipase.

1984 • 95 citations

Pancreatic amylase secretion and cytoplasmic free calcium. Effects of ionomycin, phorbol dibutyrate and diacylglycerols alone and in combination

1985 • 95 citations

Characterization of formylmethionyl-leucyl-phenylalanine stimulation of inositol trisphosphate accumulation in rabbit neutrophils.

1985 • 82 citations

Secretagogue-induced formation of inositol phosphates in rat exocrine pancreas. Implications for a messenger role for inositol trisphosphate

1984 • 74 citations

Role of Arachidonic Acid in the Regulation of Adrenocorticotropin Release from Rat Anterior Pituitary Cell Cultures

1986 • 74 citations

Phosphatidylinositol-specific Phospholipase C in Fetal Membranes and Uterine Decidua

1981 • 66 citations

Direct demonstration of the formation of prostaglandin E2 due to phosphatidylinositol breakdown associated with stimulation of enzyme secretion in the pancreas.

1981 • 65 citations

Cellular regulatory role of leukotriene B₄: Its effects on cation homeostasis in rabbit neutrophils

1981 • 61 citations

Arachidonate Stimulates Prolactin Releasein Vitro: A Role for the Fatty Acid and Its Metabolites as Intracellular Regulator(s) in Mammotrophs*

1985 • 60 citations

Evidence for a role in stimulus--secretion coupling of prostaglandins derived from release of arachidonoyl residues as a result of phosphatidylinositol breakdown.

1980 • 59 citations

Arachidonic acid stimulates phosphoinositide hydrolysis and human placental lactogen release in an enriched fraction of placental cells.

1985 • 51 citations

Phospholipid turnover in isolated rat pancreatic acini. Consideration of the relative roles of phospholipase A2 and phospholipase C

1982 • 44 citations

Effects of carbachol and pancreozymin (cholecystokinin-octapeptide) on polyphosphoinositide metabolism in the rat pancreas in vitro

1984 • 44 citations

Thyrotropin (TSH)-Releasing Hormone Decreases Phosphatidylinositol and Increases Unesterified Arachidonic Acid in Thyrotropic Cells: Possible Early Events in Stimulation of TSH Secretion*

1984 • 42 citations

Lithium-induced accumulation of inositol 1-phosphate during cholecystokinin octapeptide- and acetylcholine-stimulated phosphatidylinositol breakdown in dispersed mouse pancreas acinar cells.

1984 • 42 citations

On the mechanism by which hormones induce the release of Ca2+ from mitochondria in the liver cell

1982 • 42 citations

Effects of lithium on angiotensin‐stimulated phosphatidylinositol turnover and aldosterone production in adrenal glomerulosa cells: a possible causal relationship

1984 • 40 citations

Arachidonic acid inhibits thyrotropin-releasing hormone-induced elevation of cytoplasmic free calcium in GH3 pituitary cells.

1985 • 37 citations

Direct evidence that burst but not sustained secretion of prolactin stimulated by thyrotropin-releasing hormone is dependent on elevation of cytoplasmic calcium.

1985 • 36 citations

Effects of Hydroxyeicosatetraenoic Acids on Fatty Acid Esterification in Phospholipids and Insulin Secretion in Pancreatic Islets*

1985 • 31 citations

Stimulation of inositol trisphosphate accumulation and amylase secretion by caerulein in pancreatic acini.

1984 • 31 citations

The effect of corticotropin on phospholipid metabolism in isolated adrenocortical cells

1978 • 27 citations

In vitro stimulation of prostaglandin synthesis in the rat pancreas by carbamylcholine, caerulein and secretin

1981 • 20 citations

Arachidonic acid metabolim in rat pancreatic acinar cells: Calcium-mediated stimulation of the lipoxygenase system

1982 • 19 citations

Arachidonic acid stimulates 45calcium efflux and hPL release in isolated trophoblast cells

1986 • 18 citations

The turnover of [1-14C]eicosapentaenoic acid among individual phospholipids of human platelets

1983 • 9 citations

Effects of arachidonic acid on the metabolism of eicosapentaenoic acid in washed human platelets

1985 • 3 citations