Detection of Minimal Residual Acute Lymphoblastic Leukemia by Immunological Marker Analysis: Possibilities and Limitations

Protides of the Biological Fluids

1969 • 1,623 citations

Two populations of Ia-like molecules on a human B cell line.

1980 • 1,112 citations

A monoclonal antibody to human acute lymphoblastic leukaemia antigen

1980 • 748 citations

Immunoglobulin-Gene Rearrangements as Unique Clonal Markers in Human Lymphoid Neoplasms

1983 • 621 citations

Immunoglobulin gene rearrangement and cell surface antigen expression in acute lymphocytic leukemias of T cell and B cell precursor origins.

1983 • 605 citations

Reactivity of Langerhans cells with hybridoma antibody.

1981 • 560 citations

Insertion of N regions into heavy-chain genes is correlated with expression of terminal deoxytransferase in B cells

1984 • 540 citations

B4, a human B lymphocyte-associated antigen expressed on normal, mitogen-activated, and malignant B lymphocytes.

1983 • 517 citations

A human thymocyte antigen defined by a hybrid myeloma monoclonal antibody

1979 • 506 citations

Terminal deoxynucleotidyl transferase as a hematopoietic cell marker

1979 • 504 citations

Immunoglobulin gene rearrangement as a diagnostic criterion of B-cell lymphoma.

1984 • 464 citations

Pre-B-Cell Leukemia

1978 • 428 citations

Surface markers on leukemia and lymphoma cells: recent advances

1982 • 419 citations

Surface markers on leukemia and lymphoma cells: recent advances

1982 • 411 citations

Distribution of t lymphocyte subsets in the human bone marrow and thymus: an analysis with monoclonal antibodies.

1981 • 275 citations

Selective expression of the common acute lymphoblastic leukemia (gp 100) antigen on immature lymphoid cells and their malignant counterparts

1983 • 246 citations

Terminal Transferase-Positive Human Bone Marrow Cells Exhibit the Antigenic Phenotype of Common Acute Lymphoblastic Leukemia

1979 • 243 citations

Somatic rearrangement of T-cell antigen receptor gene in human T-cell malignancies.

1985 • 239 citations

Expression of common acute lymphoblastic leukemia antigen (CALLA) by lymphomas of B-cell and T-cell lineage

1981 • 226 citations

Cell surface characterization of malignant T cells from lymphoblastic lymphoma using monoclonal antibodies: evidence for phenotypic differences between malignant T cells from patients with acute lymphoblastic leukemia and lymphoblastic lymphoma

1981 • 226 citations

Phenotypic heterogeneity and cellular origins of T cell malignancies

1981 • 200 citations

Characterization of a monoclonal antibody that defines an immunoregulatory T cell subset for immunoglobulin synthesis in humans.

1980 • 176 citations

A monoclonal antibody (WT1) for detecting leukemias of T-cell precursors (T-ALL)

1983 • 171 citations

Cellular phenotypes of normal and leukemic hemopoietic cells determined by analysis with selected antibody combinations

1980 • 167 citations

Detection of Small Numbers of Monoclonal B Lymphocytes in the Blood of Patients with Lymphoma

1979 • 164 citations

Heavy chain immunoglobulin gene rearrangement in acute nonlymphocytic leukemia

1984 • 163 citations

Terminal Transferase Enzyme Assay and Immunological Membrane Markers in the Diagnosis of Leukaemia: a Multiparameter Analysis of 300 Cases

1980 • 154 citations

Delineation of human thymocyte differentiation pathways utilizing double-staining techniques with monoclonal antibodies.

1981 • 144 citations

Rearrangement of the T-Cell Receptor β-Chain Gene in Non-T-Cell, Non-B-Cell Acute Lymphoblastic Leukemia of Childhood

1985 • 144 citations

Acute lymphoblastic leukaemia associated antigen. IV Expression on non-leukaemic ‘lymphoid’ cells

1980 • 140 citations

Granulocytes and cultured human fibroblasts express common acute lymphoblastic leukemia-associated antigens

1983 • 136 citations

Genes encoding the Ti β subunit of the antigen/MHC receptor undergo rearrangement during intrathymic ontogeny prior to surface T3-Ti expression

1984 • 134 citations

Terminal deoxynucleotidyl transferase in the diagnosis of leukemia and malignant lymphoma

1978 • 133 citations

Monoclonal antibody characterization of surface antigens in childhood T- cell lymphoid malignancies

1983 • 132 citations

Clinics in Haematology

1981 • 125 citations

Terminal Deoxynucleotidyl Transferase Activity in Malignant Lymphomas

1977 • 120 citations

Rearrangement of immunoglobulin heavy chain genes in T cell acute lymphoblastic leukemia

1985 • 119 citations

Selective killing of leukaemia cells by antibody–toxin conjugates: implications for autologous bone marrow transplantation

1982 • 118 citations

Immunoglobulin gene organisation and expression in haemopoietic stem cell leukaemia.

1983 • 112 citations

T lymphocyte characteristics in bone marrow-transplanted patients. II. Analysis with monoclonal antibodies.

1981 • 111 citations

Demonstration of terminal deoxynucleotidyl transferase in thymocytes by immunofluorescence.

1977 • 105 citations

Immunological monitoring of residual disease in treated thymic acute lymphoblastic leukaemia

1981 • 104 citations

Human bone marrow cells positive for terminal deoxynucleotidyl transferase (TdT), HLA-DR, and a T cell marker may represent prothymocytes.

1985 • 92 citations

Circulating Monoclonal B Lymphocytes in Non-Hodgkin's Lymphoma

1984 • 91 citations

Acute lymphoblastic leukaemia associated antigen. III Alterations in expression during treatment and in relapse

1980 • 87 citations

Improved prognosis for patients with mediastinal lymphoblastic lymphoma

1979 • 84 citations

Minimal Residual Disease in Acute Leukemia

1984 • 81 citations

Derivation of lymphoma cell lines from microscopically normal bone marrow in patients with undifferentiated lymphomas: evidence of occult bone marrow involvement

1983 • 71 citations

Polymorphic and monomorphic HLA-DR determinants on human hematopoietic progenitor cells

1984 • 67 citations

7 T cell subpopulations, monoclonal antibodies and their therapeutic applications

1982 • 65 citations

Terminal Deoxynucleotidyl Transferase in Non-Hodgkin's Lymphoma

1983 • 64 citations

Monoclonal antibodies to B cells

1983 • 62 citations

Terminal deoxynucleotidyl transferase-containing cells in peripheral blood: implications for the surveillance of patients with lymphoblastic leukemia or lymphoma in remission

1981 • 61 citations

Human T Lymphocyte Cell Surface Molecules Defined by the Workshop Monoclonal Antibodies (“T Cell Protocol”)

1984 • 59 citations

Improved detection of rare CALLA-positive cells in peripheral blood using multiparameter flow cytometry

1984 • 56 citations

Immunofluorescent and Biochemical Studies of Terminal Deoxynucleotidyl Transferase in Treated Acute Leukaemia

1981 • 48 citations

Diagnosis of meningeal involvement in patients with acute lymphoblastic leukemia: Immunofluorescence for terminal transferase

1981 • 46 citations

Immunofluorescence studies on immunoglobulins in the lymphoid cells of human peripheral blood.

1972 • 42 citations

Chromosomes and causation of human cancer and leukemia: XXVIII. Value of detailed chromosome studies on large numbers of cells in CML

1977 • 38 citations

Triple immunological staining with colloidal gold, fluorescein and rhodamine as labels

1985 • 35 citations

An Immunologic Approach for the Detection of Tumor Cells in the Peripheral Blood of Patients with Malignant Lymphoma; Implications for the Diagnosis of Minimal Disease

1979 • 34 citations

Characterization of thymocytes expressing the common acute lymphoblastic leukemia antigen

1984 • 33 citations

Detection of Minimal Residual Disease in TdT Positive T Cell Malignancies by Double Immunofluorescence Staining

1984 • 29 citations

A micromethod for determination of terminal deoxynucleotidyl transferase (TdT) in the diagnostic evaluation of acute leukemias

1980 • 28 citations

Limitations of numerical ratios for defining monoclonality of immunoglobulin light chains in B-cell lymphomas.

1985 • 27 citations

Clinical utility of initial terminal deoxynucleotidyl transferase determinations in childhood acute leukemias.

1981 • 24 citations

Changes in surface antigens on malignant T cells from lymphoblastic lymphomas at relapse: an appraisal with monoclonal antibodies and microfluorometry

1982 • 24 citations

Detection of minimal residual disease in acute leukemia: Possibilities and limitations

1985 • 23 citations

Immunological Typing of Acute Lymphoblastic Leukaemia

1983 • 23 citations

Evaluation of Cerebrospinal Fluid Mononuclear Cells Obtained from Children with Acute Lymphocytic Leukemia: Advantages of Combining Cytomorphology and Terminal Deoxynucleotidyl Transferase

1983 • 23 citations

Prognostic significance of terminal transferase activity in childhood acute lymphoblastic leukemia: a prospective analysis of 164 patients

1982 • 22 citations

Conditions enhancing the percentage and size of E rosettes formed by T lymphocytes

1978 • 22 citations

Immunological classification of T-cell acute lymphoblastic leukaemia using monoclonal antibodies

1983 • 15 citations

Immunological detection of covert leukaemic spread in mediastinal T-cell lymphoblastic lymphoma

1985 • 13 citations

Surface immunoglobulin in immunoproliferative diseases.

1978 • 13 citations

Premature chromosome condensation studies in human leukemia: 5. Prediction of early relapse

1984 • 13 citations

Demonstration of cells bearing the OKT6 determinant in human tonsil and lymph node

1983 • 12 citations

Double fluorochrome analysis of human bone marrow lymphoid cells : studies with terminal transferase and anti-T-cell monoclonal antibodies

1984 • 11 citations

Characterization of normal and regenerating bone marrow cells with a panel of monoclonal antibodies

1986 • 10 citations

Demonstration of terminal deoxynucleotidyl transferase in single cells by indirect immunofluorescence — A methodological reappraisal

1983 • 10 citations

Detection of circulating ‘terminal transferase-positive’ cells does not predict relapse in acute lymphoblastic leukemia

1984 • 10 citations

Early relapse of acute lymphoblastic leukemia is not predictable by serial biochemical assays of terminal transferase activity in cells from peripheral blood

1984 • 6 citations

Detection of Early Relapse and Minimal Residual Disease in Children with Acute Lymphoblastic Leukemia by Enumeration of Terminal Deoxynucleotidyl Transferase-Positive Cells in Peripheral Blood

1984 • 5 citations

[Immunologic determination of surface determinants on cells in the cerebrospinal fluid of children with acute lymphatic leukemia].

1984 • 3 citations

Identification and Monitoring of Terminal Deoxynucleotidyl Transferase Positive Cells in the Cerebrospinal Fluid of Children with Lymphoid Malignancies

1985 • 3 citations