Adaptive Response of Iron Absorption to Anemia, Increased Erythropoiesis, Iron Deficiency, and Iron Loading in β2-Microglobulin Knockout Mice

A novel MHC class I–like gene is mutated in patients with hereditary haemochromatosis

1996 • 3,682 citations

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

1997 • 3,130 citations

Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene

1997 • 1,178 citations

β2-Microglobulin deficient mice lack CD4−8+ cytolytic T cells

1990 • 997 citations

Serum ferritin as a measure of iron stores in normal subjects

1974 • 583 citations

The Hemochromatosis Founder Mutation in HLA-H Disrupts β2-Microglobulin Interaction and Cell Surface Expression

1997 • 481 citations

Regulators of iron balance in humans [see comments]

1994 • 457 citations

ABSORPTION AND EXCRETION OF IRON

1937 • 291 citations

Tissue distribution and clearance kinetics of non-transferrin-bound iron in the hypotransferrinemic mouse: a rodent model for hemochromatosis.

1987 • 266 citations

Iron absorption. I. Factors influencing absorption.

1958 • 256 citations

Hereditary hypotransferrinemia with hemosiderosis, a murine disorder resembling human atransferrinemia.

1987 • 225 citations

Managed care for viruses

1997 • 203 citations

Defective iron homeostasis in beta 2-microglobulin knockout mice recapitulates hereditary hemochromatosis in man.

1996 • 197 citations

beta2 knockout mice develop parenchymal iron overload: A putative role for class I genes of the major histocompatibility complex in iron metabolism.

1996 • 194 citations

Iron overload in β2-microglobulin-deficient mice

1994 • 174 citations

Food iron absorption in idiopathic hemochromatosis

1989 • 144 citations

Food iron absorption in idiopathic hemochromatosis

1989 • 142 citations

Investigation of a role for reduction in ferric iron uptake by mouse duodenum

1992 • 124 citations

Regulation of intestinal iron absorption and mucosal iron kinetics in hereditary hemochromatosis.

1991 • 121 citations

Patterns of iron storage in dietary iron overload and idiopathic hemochromatosis.

1976 • 119 citations

Iron absorption in normal subjects and patients with idiopathic haemochromatosis: relationship with serum ferritin concentration.

1975 • 106 citations

Characterization and partial purification of a ferrireductase from human duodenal microvillus membranes

1995 • 92 citations

Defect of Intestinal Mucosal Iron Uptake in Mice with Hereditary Microcytic Anemia

1972 • 79 citations

In vivo studies on the relationship between intestinal iron (Fe³⁺) absorption, hypoxia and erythropoiesis in the mouse

1988 • 74 citations

Effect of endotoxin on iron absorption

1967 • 71 citations

Iron Absorption in Idiopathic Haemochromatosis before, during, and after Venesection Therapy

1966 • 63 citations

Mucosal Uptake, Mucosal Transfer and Retention of Iron, Measured by Whole‐Body Counting

1979 • 63 citations

Role of redox systems on Fe3+ uptake by transformed human intestinal epithelial (Caco-2) cells

1994 • 60 citations

Intestinal iron-transport defect in the mouse with sex-linked anemia

1971 • 51 citations

Identification of a Mouse Homolog for the Human Hereditary Haemochromatosis Candidate Gene

1997 • 44 citations

Mechanism underlying the inhibitory effect of high calcium carbonate intake on iron bioavailability from ferrous sulphate in anaemic rats

1996 • 41 citations

A duodenal mucosal abnormality in the reduction of Fe(III) in patients with genetic haemochromatosis.

1996 • 35 citations

Hereditary haemochromatosis

1989 • 32 citations

Iron absorption and iron-binding proteins in intestinal mucosa of mice with sex linked anaemia.

1973 • 18 citations

In vivo mucosal uptake, mucosal transfer and retention of iron in mice

1997 • 15 citations