Dioxygen is the source of the mu-oxo bridge in iron ribonucleotide reductase.

Crystal structure of a bacterial non-haem iron hydroxylase that catalyses the biological oxidation of methane

1993 • 904 citations

Three-dimensional structure of the free radical protein of ribonucleotide reductase

1990 • 833 citations

Iron carriers and iron proteins

1989 • 439 citations

Proteins containing oxo-bridged dinuclear iron centers: a bioinorganic perspective

1990 • 389 citations

Haloalkene oxidation by the soluble methane monooxygenase from Methylosinus trichosporium OB3b: mechanistic and environmental implications

1990 • 371 citations

Iron and Free Radical in Ribonucleotide Reductase

1973 • 364 citations

Mechanism of Assembly of the Tyrosyl Radical-Dinuclear Iron Cluster Cofactor of Ribonucleotide Reductase

1991 • 356 citations

The Activation of Dioxygen and Homogeneous Catalytic Oxidation

1993 • 354 citations

A transient intermediate of the methane monooxygenase catalytic cycle containing an FeIVFeIV cluster

1993 • 282 citations

Stearoyl-acyl carrier protein delta 9 desaturase from Ricinus communis is a diiron-oxo protein.

1993 • 225 citations

The iron center in ribonucleotide reductase from Escherichia coli.

1980 • 215 citations

Model studies of iron-tyrosinate proteins

1985 • 215 citations

Structures of deoxy and oxy hemerythrin at 2.0 Å resolution

1991 • 206 citations

Catecholate LMCT bands as probes for the active sites of nonheme iron oxygenases

1988 • 203 citations

Identification of the stable free radical tyrosine residue in ribonucleotide reductase.

1986 • 202 citations

An ENDOR study of the tyrosyl free radical in ribonucleotide reductase from Escherichia coli

1989 • 185 citations

Catalytic mechanism of cytochrome P-450: evidence for a distal charge relay

1992 • 176 citations

Oxidation of Hydrocarbons by Methane Monooxygenases from a Variety of Microbes

1980 • 173 citations

Resolution of the reaction sequence during the reduction of O2 by cytochrome oxidase.

1993 • 143 citations

Biological and toxicological consequences of quinone methide formation

1993 • 134 citations

Purification and characterization of recombinant mouse and herpes simplex virus ribonucleotide reductase R2 subunit

1991 • 132 citations

Substitution of manganese for iron in ribonucleotide reductase from Escherichia coli. Spectroscopic and crystallographic characterization.

1992 • 128 citations

Structure-mechanism relationships in hemoproteins. Oxygenations catalyzed by chloroperoxidase and horseradish peroxidase.

1987 • 128 citations

Dioxygen-copper reactivity: generation, characterization, and reactivity of a hydroperoxodicopper(II) complex

1988 • 125 citations

Models of the reduced forms of polyiron-oxo proteins: an asymmetric, triply carboxylate bridged diiron(II) complex and its reaction with dioxygen

1991 • 124 citations

Resonance Raman evidence for oxygen exchange between the FeIV = O heme and bulk water during enzymic catalysis of horseradish peroxidase and its relation with the heme-linked ionization.

1986 • 121 citations

Characterization of the flavin reductase gene (fre) of Escherichia coli and construction of a plasmid for overproduction of the enzyme

1991 • 116 citations

Raman spectral evidence for a .mu.-oxo bridge in the binuclear iron center of ribonucleotide reductase

1982 • 108 citations

Resonance Raman studies on the blue-green-colored bovine adrenal tyrosine 3-monooxygenase (tyrosine hydroxylase). Evidence that the feedback inhibitors adrenaline and noradrenaline are coordinated to iron.

1988 • 107 citations

Characterization of C439SR1, a mutant of Escherichia coli ribonucleotide diphosphate reductase: evidence that C439 is a residue essential for nucleotide reduction and C439SR1 is a protein possessing novel thioredoxin-like activity

1992 • 101 citations

The Redox Centers of Ribonucleotide Reductase of Escherichia coli

1992 • 98 citations

Overproduction and purification of the B2 subunit of ribonucleotide reductase from Escherichia coli.

1986 • 94 citations

Electronic and resonance Raman spectra of iron(III) complexes of enterobactin, catechol, and N-methyl-2,3-dihydroxybenzamide

1978 • 94 citations

Stereochemical analysis of sulfoxides obtained by diverted desaturation

1992 • 88 citations

Pseudo 2-fold symmetry in the copper-binding domain of arthropodan haemocyanins

1989 • 83 citations

Novel diferric radical intermediate responsible for tyrosyl radical formation in assembly of the cofactor of ribonucleotide reductase

1991 • 79 citations

Proton ENDOR identification of bridging hydroxide ligands in mixed-valent diiron centers of proteins: methane monooxygenase and semimet azidohemerythrin

1993 • 76 citations

Resonance Raman spectroscopy of ribonucleotide reductase. Evidence for a deprotonated tyrosyl radical and photochemistry of the binuclear iron center

1989 • 73 citations

Activation of the iron-containing B2 protein of ribonucleotide reductase by hydrogen peroxide

1990 • 69 citations

Horseradish peroxidase-catalyzed hydroxylations: mechanistic studies

1986 • 68 citations

Metal-Oxygen Bonds in Complexes: Raman Spectra of Trisacetylacetonato and Trisoxalato Complexes of Aluminum, Gallium, and Indium

1964 • 65 citations

The active site structure of methane monooxygenase is closely related to the binuclear iron center of ribonucleotide reductase

1992 • 64 citations

Escherichia coli ribonucleotide reductase. Radical susceptibility to hydroxyurea is dependent on the regulatory state of the enzyme.

1992 • 62 citations

Protein‐radical enzymes

1993 • 58 citations

Pulsed EPR studies of mixed valent [Fe(II)Fe(III)] forms of hemerythrin and methane monooxygenase: evidence for a hydroxide bridge

1993 • 58 citations

Engineering of the iron site in ribonucleotide reductase to a self-hydroxylating monooxygenase.

1992 • 57 citations

Autocatalytic generation of Dopa in the engineered protein R2 F208Y from Escherichia coli ribonucleotide reductase and crystal structure of the Dopa-208 protein

1993 • 55 citations

Structures of the cations of Werner's green and red .mu.-amido-.mu.-peroxobis[bis(ethylenediamine)cobalt(III)] salts

1967 • 55 citations

Resonance Raman Spectra of Bovine Liver Catalase Compound II

1989 • 49 citations

The electronic structures of active sites in non-heme iron enzymes

1992 • 42 citations

Identification of a hydroxide ligand at the iron center of ribonucleotide reductase by resonance Raman spectroscopy

1987 • 34 citations

High valent iron oxo intermediates might be involved during activation of ribonucleotide reductase: Single oxygen atom donors generate the tyrosyl radical

1990 • 34 citations

[18]techniques for obtaining resonance raman spectra of metalloproteins

1993 • 25 citations

Oxygen Activation t the Diiron Center of Ribonucleotide Reductase

1991 • 24 citations

Spectroscopic characterization of iron-57-reconstituted rubrerythrin, a non-heme iron protein with structural analogies to ribonucleotide reductase

1993 • 20 citations

Assembly of the iron center-tyrosyl radical cofactor of ribonucleotide reductase

1993 • 10 citations