p22-phox-deficient chronic granulomatous disease: reconstitution by retrovirus-mediated expression and identification of a biosynthetic intermediate of gp91-phox

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1983 • 1,857 citations

Construction and use of a safe and efficient amphotropic packaging cell line

1988 • 637 citations

Purified cytochrome b from human granulocyte plasma membrane is comprised of two polypeptides with relative molecular weights of 91,000 and 22,000.

1987 • 459 citations

Cytochrome b ₅₅₈ : the Flavin-Binding Component of the Phagocyte NADPH Oxidase

1992 • 384 citations

Heterogeneous mutations in the β subunit common to the LFA-1, Mac-1, and p150,95 glycoproteins cause leukocyte adhesion deficiency

1987 • 373 citations

Cytochrome b-245 is a flavocytochrome containing FAD and the NADPH-binding site of the microbicidal oxidase of phagocytes

1992 • 351 citations

Human neutrophil cytochrome b light chain (p22-phox). Gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease.

1990 • 337 citations

Primary structure and unique expression of the 22-kilodalton light chain of human neutrophil cytochrome b.

1988 • 317 citations

Molecular basis of chronic granulomatous disease [see comments]

1991 • 290 citations

Characterization of two monoclonal antibodies against cytochrome b558 of human neutrophils

1989 • 170 citations

A missense mutation in the neutrophil cytochrome b heavy chain in cytochrome-positive X-linked chronic granulomatous disease.

1989 • 148 citations

B cell lines as models for inherited phagocytic diseases: abnormal superoxide generation in chronic granulomatous disease and giant granules in Chediak-Higashi syndrome.

1984 • 132 citations

Autosomal recessive chronic granulomatous disease caused by deletion at a dinucleotide repeat.

1991 • 119 citations

Point mutation in the cytoplasmic domain of the neutrophil p22-phox cytochrome b subunit is associated with a nonfunctional NADPH oxidase and chronic granulomatous disease.

1991 • 99 citations

Prognosis of chronic granulomatous disease.

1990 • 93 citations

Cytochrome b deficiency in an autosomal form of chronic granulomatous disease. A third form of chronic granulomatous disease recognized by monocyte hybridization.

1985 • 88 citations

Peripheral blood progenitors as a target for genetic correction of p47phox-deficient chronic granulomatous disease.

1993 • 85 citations

In vitro molecular reconstitution of the respiratory burst in B lymphoblasts from p47-phox-deficient chronic granulomatous disease.

1993 • 70 citations

Cytochrome b558-negative, autosomal recessive chronic granulomatous disease: two new mutations in the cytochrome b558 light chain of the NADPH oxidase (p22-phox).

1992 • 59 citations

Restoration of superoxide generation to a chronic granulomatous disease- derived B-cell line by retrovirus mediated gene transfer

1992 • 57 citations

Restitution of superoxide generation in autosomal cytochrome-negative chronic granulomatous disease (A22(0) CGD)-derived B lymphocyte cell lines by transfection with p22phax cDNA.

1993 • 50 citations

Molecular basis of the autosomal recessive forms of chronic granulomatous disease.

1992 • 46 citations

Superoxide production by normal and chronic granulomatous disease (CGD) patient-derived EBV-transformed B cell lines measured by chemiluminescence-based assays

1992 • 32 citations

Long-Term Expression of Retroviral-Transduced Adenosine Deaminase in Human Primitive Hematopoietic Progenitors

1993 • 31 citations

Retroviral mediated expression of CD18 in normal and deficient human bone marrow progenitor cells

1993 • 16 citations

Deleted Work

1955 • 0 citations