Vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) in normal and atherosclerotic human arteries.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Angiogenesis in cancer, vascular, rheumatoid and other disease

1995 • 7,717 citations

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

1992 • 4,631 citations

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

1996 • 4,143 citations

Tumor Cells Secrete a Vascular Permeability Factor That Promotes Accumulation of Ascites Fluid

1983 • 3,942 citations

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

1996 • 3,664 citations

Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis.

1995 • 3,139 citations

Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo

1992 • 2,293 citations

The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing

1991 • 1,991 citations

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

1993 • 1,961 citations

Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity

1995 • 1,608 citations

The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF.

1993 • 1,114 citations

Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation

1992 • 1,103 citations

Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells.

1988 • 930 citations

Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors.

1992 • 900 citations

Apoptosis in Human Atherosclerosis and Restenosis

1995 • 684 citations

Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis.

1994 • 680 citations

Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer

1995 • 622 citations

Hypoxia-induced Transcriptional Activation and Increased mRNA Stability of Vascular Endothelial Growth Factor in C6 Glioma Cells

1995 • 608 citations

Vascular endothelial growth factor. A cytokine modulating endothelial function in rheumatoid arthritis.

1994 • 570 citations

Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin.

1996 • 555 citations

Local Delivery of Vascular Endothelial Growth Factor Accelerates Reendothelialization and Attenuates Intimal Hyperplasia in Balloon-Injured Rat Carotid Artery

1995 • 551 citations

Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only.

1994 • 548 citations

Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis.

1993 • 502 citations

Meeting Highlights

1996 • 497 citations

Distribution of vascular permeability factor (vascular endothelial growth factor) in tumors: concentration in tumor blood vessels.

1991 • 495 citations

Hypoxia Induces Vascular Endothelial Growth Factor in Cultured Human Endothelial Cells

1995 • 487 citations

Vascular endothelial growth factor and glioma angiogenesis: Coordinate induction of VEGF receptors, distribution of VEGF protein and possibleIn vivo regulatory mechanisms

1994 • 464 citations

Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth.

1993 • 460 citations

Vascular endothelial growth factor induces EDRF-dependent relaxation in coronary arteries

1993 • 448 citations

Binding sites for vascular endothelial growth factor are localized on endothelial cells in adult rat tissues.

1992 • 443 citations

Vascular Endothelial Growth Factor/Vascular Permeability Factor Augments Nitric Oxide Release From Quiescent Rabbit and Human Vascular Endothelium

1997 • 406 citations

Peripheral blood T lymphocytes and lymphocytes infiltrating human cancers express vascular endothelial growth factor: a potential role for T cells in angiogenesis.

1995 • 397 citations

Basic Fibroblast Growth Factor Upregulates the Expression of Vascular Endothelial Growth Factor in Vascular Smooth Muscle Cells

1995 • 389 citations

Expression of vascular permeability factor/vascular endothelial growth factor in normal rat tissues

1993 • 369 citations

Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression.

1996 • 351 citations

Exogenous vascular endothelial growth factor induces malformed and hyperfused vessels during embryonic neovascularization.

1995 • 338 citations

Up-regulation of vascular endothelial growth factor and its receptors in von Hippel-Lindau disease-associated and sporadic hemangioblastomas.

1995 • 329 citations

Expression of the vascular endothelial growth factor (VEGF) receptor gene, KDR, in hematopoietic cells and inhibitory effect of VEGF on apoptotic cell death caused by ionizing radiation.

1995 • 311 citations

Accelerated Restitution of Endothelial Integrity and Endothelium-Dependent Function After phVEGF ₁₆₅ Gene Transfer

1996 • 250 citations

Endothelial Dysfunction in Coronary Artery Disease

1993 • 227 citations

Overexpression of Vascular Endothelial Growth Factor in the Avian Embryo Induces Hypervascularization and Increased Vascular Permeability without Alterations of Embryonic Pattern Formation

1995 • 222 citations

In the human fetus, vascular endothelial growth factor is expressed in epithelial cells and myocytes, but not vascular endothelium: implications for mode of action.

1994 • 196 citations

Use of immunohistochemical procedures in diagnosing angiosarcoma. Evaluation of 98 cases

1995 • 180 citations

Stent Endothelialization

1997 • 172 citations

Human mesangial cells and peripheral blood mononuclear cells produce vascular permeability factor

1993 • 165 citations

Vascular growth factors and receptors in capillary hemangioblastomas and hemangiopericytomas.

1996 • 123 citations

Expression of vascular endothelial growth factor and its receptor mRNA in angiosarcoma.

1995 • 83 citations

AHA president's letter.

1995 • 67 citations

Enhanced expression of CD34 messenger RNA by developing endothelial cells of mice.

1995 • 58 citations

Arterial Gene Therapy for Restenosis. St. Elizabeth's Medical Center, Tufts University School of Medicine, Boston, Massachusetts

1996 • 58 citations

Vascular growth factors and receptors in capillary hemangioblastomas and hemangiopericytomas

1996 • 18 citations