Mutations in the tyrosine phosphatase CD45 gene in a child with severe combined immunodeficiency disease

Signal transduction by lymphocyte antigen receptors

1994 • 2,145 citations

Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)

1995 • 875 citations

Mutation of Jak3 in a Patient with SCID: Essential Role of Jak3 in Lymphoid Development

1995 • 800 citations

CD45: An Emerging Role as a Protein Tyrosine Phosphatase Required for Lymphocyte Activation and Development

1994 • 733 citations

Human Severe Combined Immunodeficiency Due to a Defect in ZAP-70, a T Cell Tyrosine Kinase

1994 • 516 citations

Normal B lymphocyte development but impaired T cell maturation in CD45-Exon6 protein tyrosine phosphatase-deficient mice

1993 • 509 citations

ZAP-70 Deficiency in an Autosomal Recessive form of Severe Combined Immunodeficiency

1994 • 495 citations

Age-related changes in human blood lymphocyte subpopulations

1992 • 446 citations

CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation.

1996 • 382 citations

Regulation of B-lymphocyte negative and positive selection by tyrosine phosphatase CD45

1996 • 244 citations

Primary Immunodeficiency Diseases Report of an IUIS Scientific Committee

1999 • 204 citations

Expression of the p56^lck Y505F Mutation in CD45-Deficient Mice Rescues Thymocyte Development

1999 • 76 citations

Definition of Family of Coronin-Related Proteins Conserved Between Humans and Mice: Close Genetic Linkage Between Coronin-2 and CD45-Associated Protein

1998 • 57 citations

Evidence for down-regulation of highly expressed TCR by CD4 and CD45 on non-selected CD4⁺CD8⁺thymocytes

1996 • 13 citations

CD45 up-regulation during lymphocyte maturation

1996 • 12 citations