Evidence for frequent gene conversion in the steroid 21-hydroxylase P-450(C21) gene: implications for steroid 21-hydroxylase deficiency.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Complete nucleotide sequence of two steroid 21-hydroxylase genes tandemly arranged in human chromosome: a pseudogene and a genuine gene.

1986 • 559 citations

Two genes encoding steroid 21-hydroxylase are located near the genes encoding the fourth component of complement in man.

1985 • 492 citations

A SIMPLE MICRO CYTOTOXICITY TEST

1969 • 444 citations

CLOSE GENETIC LINKAGE BETWEEN HLA AND CONGENITAL ADRENAL HYPERPLASIA (21-HYDROXYLASE DEFICIENCY)

1977 • 372 citations

Mapping of steroid 21-hydroxylase genes adjacent to complement component C4 genes in HLA, the major histocompatibility complex in man.

1985 • 371 citations

HLA-linked congenital adrenal hyperplasia results from a defective gene encoding a cytochrome P-450 specific for steroid 21-hydroxylation.

1984 • 291 citations

Frequent deletion and duplication of the steroid 21-hydroxylase genes.

1986 • 128 citations

Gene Conversion in Salt-Losing Congenital Adrenal Hyperplasia with Absent Complement C4B Protein*

1986 • 127 citations

The detection of the heterozygous carrier for congenital virilizing adrenal hyperplasia

1977 • 93 citations

B-Lymphoid cell lines derived fromHLA-D homozygous donors

1979 • 68 citations

Evidence that polymorphism in the murine major histocompatibility complex may be generated by the assortment of subgene sequences.

1985 • 55 citations

Recent Advances in 21-Hydroxylase Deficiency

1984 • 43 citations

Lethal deletion of the complement component C4 and steroid 21-hydroxylase genes in the mouse H-2 class III region, caused by meiotic recombination.

1987 • 39 citations

Genetics of steroid 21-hydroxylase deficiency

1985 • 10 citations

HLA-LINKED CONGENITAL ADRENAL HYPERPLASIA RESULTS FROM A DEFECTIVE GENE ENCODING A CYTOCHROME P-450

1984 • 8 citations