1,25-Dihydroxyvitamin D3 enhances the susceptibility of breast cancer cells to doxorubicin-induced oxidative damage.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

1993 • 3,515 citations

DNA Damage and Oxygen Radical Toxicity

1988 • 1,964 citations

Inhibition of nitrite formation from hydroxylammoniumchloride: A simple assay for superoxide dismutase

1976 • 1,664 citations

Persistent oxidative stress in cancer

1995 • 1,218 citations

Adriamycin: The Role of Lipid Peroxidation in Cardiac Toxicity and Tumor Response

1977 • 1,116 citations

The origin and function of tumor-associated macrophages

1992 • 1,081 citations

Adriamycin cardiomyopathy: pathophysiology and prevention

1997 • 311 citations

Anthracycline antibiotic-stimulated superoxide, hydrogen peroxide, and hydroxyl radical production by NADH dehydrogenase.

1983 • 282 citations

The molecular action of tumor necrosis factor-alpha

1991 • 279 citations

A filter paper dye-binding assay for quantitative determination of protein without interference from reducing agents or detergents

1990 • 266 citations

DNA Topoisomerases as Anticancer Drug Targets

1990 • 195 citations

Induction of apoptosis in breast cancer cells in response to vitamin D and antiestrogens

1994 • 150 citations

Prevention of doxorubicin-induced killing of MCF-7 human breast cancer cells by oxygen radical scavengers and iron chelating agents

1986 • 143 citations

1 alpha,25-Dihydroxy-16-ene-23-yne-26,27-hexafluorocholecalciferol (Ro24-5531), a new deltanoid (vitamin D analogue) for prevention of breast cancer in the rat.

1994 • 140 citations

Further studies on the generation of reactive oxygen species from activated anthracyclines and the relationship to cytotoxic action and cardiotoxic effects

1982 • 116 citations

1,25-Dihydroxyvitamin D3 receptors identified in the rat heart

1986 • 116 citations

Sunlight--can it prevent as well as cause cancer?

1995 • 116 citations

Effects of a new synthetic vitamin D analogue, EB1089, on the oestrogen-responsive growth of human breast cancer cells

1994 • 116 citations

Inhibition of breast cancer cell growth by combined treatment with vitamin D3 analogues and tamoxifen.

1994 • 95 citations

Determinants of Response to the DNA Topoisomerase II Inhibitors Doxorubicin and Etoposide in Human Lung Cancer Cell Lines

1992 • 90 citations

Resistance to TNF-alpha and adriamycin in the human breast cancer MCF-7 cell line: relationship to MDR1, MnSOD, and TNF gene expression.

1994 • 80 citations

Menadione-induced DNA damage in a human tumor cell line

1991 • 68 citations

1,25-Dihydroxyvitamin d3 potentiates the cytotoxic effect of TNF on human breast cancer cells

1994 • 65 citations

Human Cu/Zn superoxide dismutase gene: molecular characterization of its two mRNA species

1984 • 58 citations

Experimental bases for the different hepatotoxicity of erythromycin preparations in man.

1972 • 58 citations

Comparison of dna cleavage induced by etoposide and doxorubicin in two human small‐cell lung cancer lines with different sensitivities to topoisomerase ii inhibitors

1990 • 49 citations

Doxorubicin Resistance Conferred by Selective Enhancement of Intracellular Glutathione Peroxidase or Superoxide Dismutase Content in Human MCF-7 Breast Cancer Cells

1991 • 49 citations

Impaired macrophage activation in vitamin D3 deficiency: differential in vitro effects of 1,25-dihydroxyvitamin D3 on mouse peritoneal macrophage functions.

1989 • 45 citations

Topoisomerase II as a target of antileukemia drugs: a review of controversial areas.

1989 • 44 citations

Effects of doxorubicin on cardiomyocytes with reduced level of superoxide dismutase

1995 • 43 citations

Extrarenal production of calcitriol.

1990 • 37 citations

A prospective study on the dose dependency of cardiotoxicity induced by mitomycin C

1988 • 29 citations

1,25(OH)2D3 increases cytotoxicity and exocytosis in lymphokine-activated killer cells

1993 • 26 citations

1,25-Dihydroxyvitamin D3 increases the sensitivity of human renal carcinoma cells to tumor necrosis factor α but not to interferon α or lymphokine-activated killer cells

1996 • 25 citations

Adriamycin effects on hydroperoxide metabolism and growth of human breast tumor cells

1990 • 21 citations

1,25-Dihydroxyvitamin D3 and agents that increase intracellular adenosine 3′, 5′-monophosphate synergistically inhibit fibroblast proliferation

1997 • 19 citations

Effects of amiodarone on beating rate and Na-K-ATPase activity in cultured neonatal rat heart myocytes

1995 • 14 citations