Characterization of endogenous cytokine concentrations after high-dose chemotherapy with autologous bone marrow support

The biology of interleukin-6

1989 • 1,964 citations

Effect of Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor on Hematopoietic Reconstitution after High-Dose Chemotherapy and Autologous Bone Marrow Transplantation

1988 • 779 citations

Effect of Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor on Chemotherapy-Induced Myelosuppression

1988 • 689 citations

Increased serum levels of tumor necrosis factor alpha precede major complications of bone marrow transplantation [see comments]

1990 • 591 citations

Recombinant Granulocyte-Macrophage Colony-Stimulating Factor after Autologous Bone Marrow Transplantation for Lymphoid Cancer

1991 • 509 citations

Serum levels of interleukin 6, a potent myeloma cell growth factor, as a reflect of disease severity in plasma cell dyscrasias.

1989 • 501 citations

Interleukin-6 is a potent thrombopoietic factor in vivo in mice

1989 • 422 citations

Macrophage growth factor CSF-1 stimulates human monocyte production of interferon, tumor necrosis factor, and colony stimulating activity.

1986 • 397 citations

High-dose combination alkylating agents with bone marrow support as initial treatment for metastatic breast cancer.

1988 • 384 citations

In vivo effects of recombinant human interleukin-6 in primates: stimulated production of platelets

1990 • 280 citations

Comparative effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) on priming peripheral blood progenitor cells for use with autologous bone marrow after high-dose chemotherapy

1993 • 258 citations

Human granulocyte-monocyte colony-stimulating factor and interleukin 3 stimulate monocyte cytotoxicity through a tumor necrosis factor- dependent mechanism

1988 • 221 citations

Recombinant human tumor necrosis factor administered as a five-day continuous infusion in cancer patients: phase I toxicity and effects on lipid metabolism.

1988 • 217 citations

Clinical pharmacology of recombinant human tumor necrosis factor in patients with advanced cancer.

1987 • 216 citations

Serum interleukin-6 levels correlate with disease status in patients with epithelial ovarian cancer

1991 • 214 citations

Granulocyte-macrophage colony-stimulating factor induces cytokine secretion by human polymorphonuclear leukocytes.

1989 • 201 citations

Phase I-II trial of pentoxifylline for the prevention of transplant- related toxicities following bone marrow transplantation [published erratum appears in Blood 1992 Jun 15;79(12):3397] [see comments]

1991 • 200 citations

Inducible production of interleukin-6 by human polymorphonuclear neutrophils: role of granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-alpha

1990 • 193 citations

Human interleukin-6 supports granulocytic differentiation of hematopoietic progenitor cells and acts synergistically with GM-CSF

1989 • 157 citations

Phase I trial of recombinant human macrophage colony-stimulating factor in patients with invasive fungal infections

1991 • 156 citations

Stimulation of thrombopoiesis in mice by human recombinant interleukin 6.

1990 • 151 citations

Interleukin-6 is a prognostic factor in multiple myeloma [letter] [see comments]

1991 • 145 citations

Quantitation and identification of human monocytic colony-stimulating factor in human serum by enzyme-linked immunosorbent assay

1988 • 139 citations

Elevated serum interleukin‐6 levels in patients with reactive thrombocytosis

1991 • 124 citations

Inhibition of interleukin-2-induced tumor necrosis factor release by dexamethasone: prevention of an acquired neutrophil chemotaxis defect and differential suppression of interleukin-2-associated side effects [see comments]

1990 • 109 citations

Characterization of the clinical effects after the first dose of bacterially synthesized recombinant human granulocyte-macrophage colony- stimulating factor

1989 • 106 citations

Serum erythropoietin levels in patients receiving intensive chemotherapy and radiotherapy

1990 • 100 citations

Marked erythropoietin increase before fall in Hb after treatment with cytostatic drugs suggests mechanism other than anaemia for stimulation

1989 • 98 citations

Macrophage colony-stimulating factor in murine candidiasis: serum and tissue levels during infection and protective effect of exogenous administration

1991 • 95 citations

Circulating levels of CSF-1 (M-CSF) a lymphohematopoietic cytokine may be a useful marker of disease status in patients with malignant ovarian neoplasms

1989 • 93 citations

Circulating erythropoietin levels after bone marrow transplantation: inappropriate response to anemia in allogeneic transplants

1991 • 81 citations

Increased serum levels of macrophage colony-stimulating factor in ovarian cancer

1991 • 79 citations

Circulating granulocyte colony-stimulating factor (G-CSF) levels after allogeneic and autologous bone marrow transplantation: endogenous G-CSF production correlates with myeloid engraftment [see comments]

1992 • 73 citations

Radioimmunoassay for the measurement of serum IL‐6 and its correlation with tumour cell mass parameters in multiple myeloma

1992 • 70 citations

The effect of recombinant human colony-stimulating factors on hematopoietic reconstitution following autologous bone marrow transplantation.

1989 • 62 citations

Is interleukin 6 the physiological regulator of thrombopoiesis?

1992 • 34 citations

Lymphokine profile in bone marrow transplant recipients

1991 • 33 citations

Hematopoietic growth factors in bone marrow transplantation.

1990 • 32 citations

The impact of myeloid growth factors on engraftment following autologous bone marrow transplantation for malignant lymphoma.

1991 • 32 citations

Serum levels of tumor necrosis factor alpha in patients treated with granulocyte-macrophage colony-stimulating factor [letter; comment]

1990 • 31 citations

Changes in serum erythropoietin levels during allogeneic bone marrow transplantation

1991 • 25 citations

[Effect of quinolones on TNF-alpha production by human monocytes].

1990 • 5 citations