Kinetics of the hydroperoxide-dependent dealkylation reactions catalyzed by rabbit liver microsomal cytochrome P-450.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 11,832 citations

Enzyme kinetics; behavior and analysis of rapid equilibrium and steady state enzyme systems

1994 • 3,007 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products☆I. Nomenclature and rate equations

1963 • 2,095 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products

1963 • 1,885 citations

Enzyme Kinetics Behavior and analysis of rapid equilibrium and steady state enzyme systems

1975 • 1,447 citations

Some properties of a detergent-solubilized NADPH-cytochrome c(cytochrome P-450) reductase purified by biospecific affinity chromatography.

1976 • 1,180 citations

Spectral studies of drug interaction with hepatic microsomal cytochrome.

1967 • 1,126 citations

Molecular Mechanisms of Oxygen Activation

1974 • 879 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products☆II. Inhibition: Nomenclature and theory

1963 • 865 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products

1963 • 774 citations

Role of Hemoprotein P-450 in Fatty Acid ω-Hydroxylation in a Soluble Enzyme System from Liver Microsomes

1968 • 625 citations

Preparation and Properties of Partially Purified Cytochrome P-450 and Reduced Nicotinamide Adenine Dinucleotide Phosphate-Cytochrome P-450 Reductase from Rabbit Liver Microsomes

1974 • 518 citations

Microsomes, Drug Oxidations and Chemical Carcinogenesis

1980 • 498 citations

Phosphatidylcholine Requirement in the Enzymatic Reduction of Hemoprotein P-450 and in Fatty Acid, Hydrocarbon, and Drug Hydroxylation

1970 • 462 citations

Cytochrome P-450 and its Role in Drug Metabolism

1972 • 392 citations

Studies on hydroperoxide-dependent substrate hydroxylation by purified liver microsomal cytochrome P-450

1976 • 339 citations

A new spectral intermediate associated with cytochrome P-450 function in liver microsomes

1971 • 240 citations

Microsomal-catalyzed hydroperoxide-dependent C-oxidation of amines

1973 • 193 citations

Effect of Superoxide Generation and Dismutation on Hydroxylation Reactions Catalyzed by Liver Microsomal Cytochrome P-450

1971 • 189 citations

Preparation of homogeneous NADPH-cytochrome P-450 reductase from rat liver

1975 • 186 citations

Biological hydroxylation mechanisms

1973 • 186 citations

Cytochrome P450 as an oxene transferase

1976 • 176 citations

Hydroperoxide catalyzed liver microsomal aromatic hydroxylation reactions involving cytochrome P-450

1974 • 173 citations

Highly purified detergent-solubilized NADPH-cytochrome P-450 reductase from phenobarbital-induced rat liver microsomes

1974 • 171 citations

Oxygenated cytochrome P-450 and its possible role in enzymic hydroxylation

1971 • 160 citations

Multiple forms of cytochrome P-450 in phenobarbital- and 3-methylcholanthrene-treated rats. Separation and spectral properties.

1975 • 150 citations

The preparation of microsomal fractions of rodent respiratory tract and their characterization.

1974 • 139 citations

Microsomes and Drug Oxidations

1977 • 131 citations

Biochemistry of the Phagocytic Process

1972 • 123 citations

Studies on Cytochrome c Peroxidase

1966 • 119 citations

The Involvement of Cytochrome P-450 in Hepatic Microsomal Steroid Hydroxylation Reactions Supported by Sodium Periodate, Sodium Chlorite, and Organic Hydroperoxides

1976 • 115 citations

Hydroperoxide dependent O-dealkylation reactions catalyzed by liver microsomal cytochrome P450

1975 • 107 citations

Laboratory methods in porphyrin and metalloporphyrin research

1975 • 105 citations

Indoleamine 2,3-dioxygenase. Potassium superoxide as substrate.

1977 • 98 citations

Improved Iodometric Method of Analysis for tert-Butyl Peresters

1958 • 93 citations

Ligand partitioning into membranes: Its significance in determining K_M and K_S values for cytochrome P‐450 and other membrane bound receptors and enzymes

1976 • 92 citations

On the mechanism of action of cytochrome P-450. Spectral intermediates in the reaction of P-450LM2 with peroxy compounds.

1980 • 77 citations

Studies on the Substrate-induced Spectral Change of Cytochrome P-450 in Liver Microsomes1

1975 • 67 citations

P-450cam hydroxylase: substrate-effector and electron-transport reactions

1971 • 51 citations

The Mechanism of Action of Cytochrome P-450. Occurrence of the 'NIH Shift' during Hydroperoxide-Dependent Aromatic Hydroxylations

1978 • 47 citations

TURNIP PEROXIDASE

1960 • 28 citations

Mechanism of aliphatic hydroxylation tetralin hydroperoxide as an intermediate in the hydroxylation of tetralin in rat-liver homogenate

1968 • 27 citations

Pseudomonas Cytochrome c Peroxidase. XI. Kinetics of the Peroxidatic Oxidation of Pseudomonas Respiratory Chain Components.

1975 • 26 citations

[9-14C]fluorene hydroperoxide as a possible intermediate in the hydroxylation of [9-3C]fluorene by rat liver homogenate

1969 • 24 citations

Liver microsomal metabolism of N-methylcarbazole: structural identification of the four major metabolites of N-methylcarbazole using 1H Fourier transform NMR spectroscopy.

1980 • 21 citations

Effect of washing the hepatic microsomal fraction in sucrose solutions and in sucrose solution containing edta upon the metabolism of foreign compounds

1975 • 14 citations

Transannular dioxygenation of 9,10-dimethyl-1,2-benzanthracene by cytochrome P-450 oxygenase of rat liver

1976 • 13 citations

The mechanism of ferrocytochrome C oxidation by a horseradish isoperoxidase

1975 • 10 citations

Kinetics of hydroperoxyde-dependent naphthalene hydroxylation involving cytochrome P-450 of the intact and induced enzyme systems of rat liver microsomes

1977 • 1 citations