The human growth hormone gene contains both positive and negative control elements.

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region

1985 • 1,244 citations

An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter

1985 • 763 citations

Factors involved in specific transcription by human RNA polymerase II: analysis by a rapid and quantitative in vitro assay.

1985 • 575 citations

Characterization of a “silencer” in yeast: A DNA sequence with properties opposite to those of a transcriptional enhancer

1985 • 531 citations

Enhancers and eukaryotic gene transcription

1985 • 515 citations

A single polypeptide possesses the binding and transcription activities of the adenovirus major late transcription factor.

1986 • 412 citations

The human β-interferon gene enhancer is under negative control

1986 • 395 citations

[35] In Vitro transcription: Whole-cell extract

1983 • 311 citations

A pituitary-specific trans-acting factor can stimulate transcription from the growth hormone promoter in extracts of nonexpressing cells

1987 • 301 citations

Activation of the yeast HO gene by release from multiple negative controls

1987 • 257 citations

Transcriptional "silencer" element in rat repetitive sequences associated with the rat insulin 1 gene locus.

1986 • 257 citations

Regulation of rat insulin 1 gene expression: evidence for negative regulation in nonpancreatic cells.

1986 • 178 citations

The Adenovirus Major Late Transcription Factor Activates the Rat γ-Fibrinogen Promoter

1987 • 177 citations

Isolation of a Saccharomyces cerevisiae centromere DNA-binding protein, its human homolog, and its possible role as a transcription factor.

1987 • 158 citations

The human growth hormone gene is negatively regulated by triiodothyronine when transfected into rat pituitary tumor cells.

1986 • 82 citations

Regulated expression of chimaeric genes containing the 5′-flanking regions of human growth hormone-related genes in transiently transfected rat anterior pituitary tumor cells

1987 • 55 citations

The 5′-Flanking Sequences of the Human Growth Hormone Gene Contain a Cell-Specific Control Element

1986 • 28 citations