The fifth transmembrane segment of the neuromedin B receptor is critical for high affinity neuromedin B binding

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides

1983 • 1,937 citations

MODEL SYSTEMS FOR THE STUDY OF SEVEN-TRANSMEMBRANE-SEGMENT RECEPTORS

1991 • 1,357 citations

Basic methods in molecular biology

1987 • 842 citations

Chimeric α ₂ -,β ₂ -Adrenergic Receptors: Delineation of Domains Involved in Effector Coupling and Ligand Binding Specificity

1988 • 766 citations

Identification of Two Serine Residues Involved in Agonist Activation of the β-Adrenergic Receptor

1989 • 522 citations

Molecular cloning of the bombesin/gastrin-releasing peptide receptor from Swiss 3T3 cells.

1991 • 330 citations

cDNA cloning, characterization, and brain region-specific expression of a neuromedin-B-preferring bombesin receptor

1991 • 288 citations

Extracellular domain of lutropin/choriogonadotropin receptor expressed in transfected cells binds choriogonadotropin with high affinity.

1990 • 237 citations

Two distinct bombesin receptor subtypes are expressed and functional in human lung carcinoma cells.

1991 • 230 citations

Site-directed mutagenesis of alpha 2A-adrenergic receptors: identification of amino acids involved in ligand binding and receptor activation by agonists.

1991 • 221 citations

Localization of agonist and antagonist binding domains of the human neurokinin-1 receptor.

1992 • 190 citations

Effects of bombesin and insulin on inositol (1,4,5) trisphosphate and inositol (1,3,4) trisphosphate formation in Swiss 3T3 cells

1986 • 185 citations

Thyrotropin-luteinizing hormone/chorionic gonadotropin receptor extracellular domain chimeras as probes for thyrotropin receptor function.

1991 • 183 citations

An Insertion in the Human Thyrotropin Receptor Critical for High Affinity Hormone Binding

1990 • 153 citations

Serine mutations in transmembrane V of the dopamine D1 receptor affect ligand interactions and receptor activation.

1992 • 102 citations

Delineation of structural domains involved in the subtype specificity of tachykinin receptors through chimeric formation of substance P/substance K receptors.

1992 • 97 citations

Role of conserved threonine and tyrosine residues in acetylcholine binding and muscarinic receptor activation. A study with m3 muscarinic receptor point mutants.

1992 • 92 citations

Identification of the bombesin receptor on murine and human cells by cross-linking experiments.

1987 • 88 citations

Selective binding of ligands to beta 1, beta 2 or chimeric beta 1/beta 2-adrenergic receptors involves multiple subsites.

1990 • 76 citations

Neuromedin B receptors retain functional expression when transfected into BALB 3T3 fibroblasts: analysis of binding, kinetics, stoichiometry, modulation by guanine nucleotide-binding proteins, and signal transduction and comparison with natively expressed receptors.

1992 • 65 citations