Spontaneous and UV-induced mutations in Escherichia coli K-12 strains with altered or absent DNA polymerase I

Experiments in molecular genetics

1972 • 28,260 citations

Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli

1984 • 1,608 citations

The distribution of the numbers of mutants in bacterial populations

1949 • 1,471 citations

RecA-mediated cleavage activates UmuD for mutagenesis: mechanistic relationship between transcriptional derepression and posttranslational activation.

1988 • 415 citations

BASE-CHANGE MUTAGENESIS AND PROPHAGE INDUCTION IN STRAINS OF ESCHERICHIA COLI WITH DIFFERENT DNA REPAIR CAPACITIES

1970 • 405 citations

UmuD mutagenesis protein of Escherichia coli: overproduction, purification, and cleavage by RecA.

1988 • 354 citations

RecA protein-dependent cleavage of UmuD protein and SOS mutagenesis.

1988 • 349 citations

Method for determining whether a gene of Escherichia coli is essential: application to the polA gene

1984 • 256 citations

Mutagenic repair in Escherichia coli: products of the recA gene and of the umuD and umuC genes act at different steps in UV-induced mutagenesis.

1985 • 166 citations

Specificity of mutagenesis resulting from the induction of the SOS system in the absence of mutagenic treatment

1984 • 146 citations

Repair of damage induced by ultraviolet light in DNA polymerase-defective Escherichia coli cells

1971 • 139 citations

Capacity of RecA protein to bind preferentially to UV lesions and inhibit the editing subunit (epsilon) of DNA polymerase III: a possible mechanism for SOS-induced targeted mutagenesis.

1986 • 137 citations

Radiation-sensitive mutants of T4D I. T4y: A new radiation-sensitive mutant: Effect of the mutation on radiation survival, growth and recombination

1969 • 127 citations

Ultraviolet mutagenesis in polA and UvrA polA derivatives of Escherichia coli B-R: evidence for an inducible error-prone repair system.

1973 • 124 citations

Mutagenic DNA repair in Escherichia coli

1976 • 120 citations

Purification and characterization of an inducible Escherichia coli DNA polymerase capable of insertion and bypass at abasic lesions in DNA.

1988 • 118 citations

Persistence of Deoxyribonucleic Acid Polymerase I and Its 5′ → 3′ Exonuclease Activity in PolA Mutants of Escherichia coli K12

1973 • 114 citations

Derepression of specific genes promotes DNA repair and mutagenesis in Escherichia coli

1988 • 74 citations

Mutagenesis resulting from depurination is an SOS process

1982 • 63 citations

Spontaneous and radiation-induced deletion mutations in Escherichia coli strains with different DNA repair capacities

1972 • 56 citations

Isolation of an altered form of DNA polymerase I from Escherichia coli cells induced for recA/lexA functions.

1982 • 45 citations

Requirement for either DNA polymerase I or DNA polymerase III in post-replication repair in excision-proficient Escherichia coli

1974 • 44 citations

Involvement of DNA polymerase III in UV-induced mutagenesis of bacteriophage lambda

1985 • 43 citations

Characterization of DNA polymerase I*, a form of DNA polymerase I found in Escherichia coli expressing SOS functions.

1985 • 38 citations

Plasmid pKM101-mediated mutagenesis in Escherichia coli is inducible

1982 • 34 citations

Ultraviolet Mutagenesis in Strains of E. coli deficient in DNA Polymerase

1971 • 29 citations