Monitoring of Immunosuppressive Therapy in Renal Transplanted Patients

A RANDOMIZED DOUBLE-BLIND, MULTICENTER PLASMA CONCENTRATION CONTROLLED STUDY OF THE SAFETY AND EFFICACY OF ORAL MYCOPHENOLATE MOFETIL FOR THE PREVENTION OF ACUTE REJECTION AFTER KIDNEY TRANSPLANTATION1

1999 • 533 citations

Clinical Pharmacokinetics of Everolimus

2004 • 476 citations

NEORAL MONITORING BY SIMPLIFIED SPARSE SAMPLING AREA UNDER THE CONCENTRATION-TIME CURVE

1999 • 399 citations

Mycophenolic acid binding to human serum albumin: characterization and relation to pharmacodynamics

1995 • 311 citations

RELATIONSHIP OF FK506 WHOLE BLOOD CONCENTRATIONS AND EFFICACY AND TOXICITY AFTER LIVER AND KIDNEY TRANSPLANTATION

1996 • 300 citations

Therapeutic drug monitoring of immunosuppressant drugs in clinical practice

2002 • 287 citations

Mycophenolate Mofetil Dose Reduction and the Risk of Acute Rejection after Renal Transplantation

2003 • 278 citations

Clinical pharmacokinetics and therapeutic drug monitoring of sirolimus

2000 • 277 citations

Pharmacokinetics of Sirolimus in Stable Renal Transplant Patients after Multiple Oral Dose Administration

1997 • 212 citations

REDUCED INTER- AND INTRASUBJECT VARIABILITY IN CYCLOSPORINE PHARMACOKINETICS IN RENAL TRANSPLANT RECIPIENTS TREATED WITH A MICROEMULSION FORMULATION IN CONJUNCTION WITH FASTING, LOW-FAT MEALS, OR HIGH-FAT MEALS1,2

1995 • 202 citations

The impact of mycophenolate mofetil dosing patterns on clinical outcome after renal transplantation

2003 • 197 citations

Low systemic exposure to tacrolimus correlates with acute rejection

1999 • 183 citations

Pharmacokinetics of mycophenolate mofetil (RS61443): a short review.

1996 • 182 citations

EFFECT OF CYCLOSPORINE ON MYCOPHENOLIC ACID TROUGH LEVELS IN KIDNEY TRANSPLANT RECIPIENTS1

1999 • 173 citations

Influence of a fat-rich meal on the pharmacokinetics of a new oral formulation of cyclosporine in a crossover comparison with the market formulation.

1994 • 173 citations

Mycophenolic Acid Area under the Curve Values in African American and Caucasian Renal Transplant Patients Are Comparable

2000 • 134 citations

Clinical validation studies of neoral C2 monitoring: a review

2002 • 128 citations

Therapeutic monitoring of mycophenolic acid

1998 • 127 citations

Pharmacokinetics and Concentration-Control Investigations of Mycophenolic Acid in Adults After Transplantation

2000 • 121 citations

Current opinions on therapeutic drug monitoring of immunosuppressive drugs

1999 • 115 citations

Pharmacokinetics of tacrolimus-based combination therapies

2003 • 108 citations

A PHASE I STUDY OF A 4-WEEK COURSE OF SDZ-RAD (RAD) IN QUIESCENT CYCLOSPORINE-PREDNISONE-TREATED RENAL TRANSPLANT RECIPIENTS1,2

1999 • 108 citations

Maintenance immunosuppression in the renal transplant recipient: An overview

2001 • 104 citations

Inhibition of Stimulated Interleukin-2 Production in Whole Blood: A Practical Measure of Cyclosporine Effect

1999 • 95 citations

Differential Influence of Two Cyclosporine Formulations on Everolimus Pharmacokinetics: A Clinically Relevant Pharmacokinetic Interaction

2002 • 87 citations

Pharmacokinetics of tacrolimus: clinically relevant aspects

1999 • 78 citations

Opportunities for therapeutic monitoring of mycophenolate mofetil dose in renal transplantation suggested by the pharmacokinetic/pharmacodynamic relationship for mycophenolic acid and suppression of rejection

1998 • 77 citations

Augmentation of mycophenolate mofetil pharmacokinetics in renal transplant patients receiving prograf and cellcept in combination therapy

1997 • 73 citations

Universal approach to pharmacokinetic monitoring of immunosuppressive agents in children

2002 • 71 citations

Abbreviated mycophenolic acid AUC from C0, C1, C2, and C4 is preferable in children after renal transplantation on mycophenolate mofetil and tacrolimus therapy

2004 • 70 citations

Prediction of cyclosporine area under the curve using a three-point sampling strategy after Neoral administration.

1997 • 63 citations

Evaluation of Limited Sampling Strategies for Estimation of 12-Hour Mycophenolic Acid Area Under the Plasma Concentration???Time Curve in Adult Renal Transplant Patients

2000 • 61 citations

Two‐hour post‐dose cyclosporine level is a better predictor than trough level of acute rejection of renal allografts

2002 • 58 citations

Conversion from liquid to solid rapamycin formulations in stable renal allograft transplant recipients

1999 • 35 citations

Therapeutic monitoring of sirolimus: its contribution to optimal prescription

2003 • 33 citations

C2 single-point sampling to evaluate cyclosporine exposure in long-term renal transplant recipients

2001 • 32 citations

Effect of bile flow on the absorption of tacrolimus in liver allograft transplantation

2002 • 28 citations

Immunosuppressive drug monitoring of sirolimus and cyclosporine in pediatric patients

2004 • 25 citations

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