Construction and mapping of recombinant plasmids used for the preparation of DNA fragments containing the Escherichia coli lactose operator and promoter.

Experiments in molecular genetics

1972 • 28,260 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Calcium-dependent bacteriophage DNA infection

1970 • 2,743 citations

Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose-ethidium bromide electrophoresis

1973 • 1,616 citations

Nature of Col E ₁ Plasmid Replication in Escherichia coli in the Presence of Chloramphenicol

1972 • 1,202 citations

A Restriction enzyme from Hemophilus influenzae

1970 • 859 citations

Properties of a supercoiled deoxyribonucleic acid-protein relaxation complex and strand specificity of the relaxation event

1970 • 770 citations

Filamentous coliphage M13 as a cloning vehicle: insertion of a HindII fragment of the lac regulatory region in M13 replicative form in vitro.

1977 • 711 citations

Analysis of Endonuclease R· Eco RI Fragments of DNA from Lambdoid Bacteriophages and Other Viruses by Agarose-Gel Electrophoresis

1974 • 633 citations

A simple method for the preparation of large quantities of pure plasmid DNA

1975 • 586 citations

Genetic Regulation: The Lac Control Region

1975 • 523 citations

Construction of a colicin E1-R factor composite plasmid in vitro: means for amplification of deoxyribonucleic acid

1975 • 449 citations

Construction of plasmids carrying the cI gene of bacteriophage lambda.

1976 • 410 citations

Polynucleotides. CXXIII. Physical characterization and simultaneous purification of bacteriophage T4 induced polynucleotide kinase, polynucleotide ligase, and deoxyribonucleic acid polymerase

1973 • 293 citations

Functional genetic expression of eukaryotic DNA in Escherichia coli.

1976 • 261 citations

Origin of replication of colicin E1 plasmid DNA.

1977 • 212 citations

Characterization of a mini-ColC1 plasmid

1976 • 196 citations

Synthetic lacoperator DNA is functional in vivo

1976 • 196 citations

Plasmid Detection and Sizing in Single Colony Lysates

1977 • 190 citations

A second specific endonuclease from Haemophilus aegyptius

1975 • 190 citations

Enzymatic Joining of Polynucleotides

1970 • 156 citations

Detection of 5-methylcytosine in DNA sequences

1978 • 148 citations

A specific endonuclease from Haemophilus haemolyticus

1976 • 145 citations

The Role of DNA Structure in Genetic Regulatio

1977 • 144 citations

‘Single-stranded’ DNA from φX174 and M13 is cleaved by certain restriction endonucleases

1975 • 134 citations

Repressors

1976 • 132 citations

In vitro analysis of the Escherichia coli RNA polymerase interaction with wild-type and mutant lactose promoters

1978 • 121 citations

A specific endonuclease from Arthrobacter luteus

1976 • 118 citations

The Location of the Repressor Binding Sites in the lac Operon

1974 • 112 citations

Origin of replication of pBR345 plasmid DNA.

1977 • 106 citations

Enzymatic Oligomerization of Bacteriophage P22 DNA and of Linear Simian Virus 40 DNA

1972 • 99 citations

Cloned synthetic lac operator DNA is biologically active

1976 • 79 citations

Nucleotide sequence changes produced by mutations in the lac promoter of Escherichia coli

1977 • 74 citations

Preparative fractionation of DNA restriction fragments by reversed phase column chromatography.

1976 • 71 citations

Cleavage map of colicin E1 plasmid

1976 • 69 citations

Micrococcus luteus Deoxyribonucleic Acid Polymerase

1970 • 63 citations

High resolution electron microscopic studies of genetic regulation

1976 • 61 citations

RNA polymerase binding sites in λp lac 5 DNA

1977 • 53 citations

Structural uniqueness of lactose operator

1974 • 49 citations

The construction of λ transducing phages containing deletions defining regulatory elements of the lac and trp operons in E. coli

1974 • 46 citations

Protein Ligand Interaction

2017 • 45 citations

Cloning of chemically synthesized lactose operators II. EcoRI-linkered operators

1978 • 41 citations

Fine cleavage map of a small colicin E1 plasmid carrying genes responsible for replication and colicin E1 immunity

1978 • 40 citations

Factors influencing fractionation of DNA restriction fragments by RPC-5 column chromatography.

1979 • 38 citations

Influence of A-T content on the fractionation of DNA restriction fragments by RPC-5 column chromatography.

1979 • 37 citations

The nucleotide sequence surrounding the origin of DNA replication of Col E₁

1977 • 30 citations

Influence of DNA structure on the lactose operator-repressor interaction

1977 • 28 citations

Properties of the Exonucleolytic Activities of the Micrococcus luteus Deoxyribonucleic Acid Polymerase

1972 • 26 citations

Identification of regions of pRZ2 which have delayed elution behavior on RPC-5 column chromatography.

1979 • 16 citations