Cloning and simplified purification of Escherichia coli DNA gyrase A and B proteins.

DNA gyrase: an enzyme that introduces superhelical turns into DNA.

1976 • 1,175 citations

Nalidixic acid resistance: A second genetic character involved in DNA gyrase activity

1977 • 828 citations

Mechanism of action of nalidixic acid: Purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme

1977 • 777 citations

Novobiocin and coumermycin inhibit DNA supercoiling catalyzed by DNA gyrase.

1976 • 719 citations

Regulation of the genes for E. coli DNA gyrase: Homeostatic control of DNA supercoiling

1983 • 458 citations

DNA gyrase: subunit structure and ATPase activity of the purified enzyme.

1978 • 282 citations

Purification of subunits of Escherichia coli DNA gyrase and reconstitution of enzymatic activity

1978 • 250 citations

DNA polymerase as a requirement for the maintenance of the bacterial plasmid colicinogenic factor E1

1970 • 239 citations

DNA gyrase: affinity chromatography on novobiocin-Sepharose and catalytic properties

1981 • 180 citations

Electron microscope heteroduplex studies of sequence relations among bacterial plasmids: identification and mapping of the insertion sequences IS1 and IS2 in F and R plasmids

1975 • 174 citations

DNA gyrase: purification and catalytic properties of a fragment of gyrase B protein.

1979 • 158 citations

The intrinsic ATPase of DNA gyrase.

1980 • 144 citations

Deoxyribonucleic acidgyrase-deoxyribonucleic acid complex containing 140 base pairs of deoxyribonucleic acid and an .alpha.2.beta.2 protein core

1980 • 131 citations

Characterization of the dnaA, gyrB and other genes in the dnaA region of the Escherichia coli chromosome on specialized transducing phages λtna

1979 • 127 citations

Phosphate-Induced Protein Chromatography

1973 • 88 citations

A thermoinducible λ phage-ColE1 plasmid chimera for the overproduction of gene products from cloned DNA segments

1978 • 66 citations